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ChemicalBook >> CAS DataBase List >> 3'-AZIDO-3'-DEOXYTHYMIDINE BETA-D-GLUCURONIDE, SODIUM SALT

3'-AZIDO-3'-DEOXYTHYMIDINE BETA-D-GLUCURONIDE, SODIUM SALT

3'-AZIDO-3'-DEOXYTHYMIDINE BETA-D-GLUCURONIDE, SODIUM SALT price.
  • $62 - $1871.1
  • Product name: 3'-AZIDO-3'-DEOXYTHYMIDINE BETA-D-GLUCURONIDE, SODIUM SALT
  • CAS: 133525-01-6
  • MF: C16H20N5NaO10
  • MW: 465.35
  • EINECS:
  • MDL Number:MFCD02091675
  • Synonyms:AZT Glucuronide SodiuM Salt;Zidovudine Glucuronide SodiuM Salt;AZT GLUCURONIDE;3'-AZIDO-3'-DEOXYTHYMIDINE BETA-D-GLUCURONIDE, SODIUM SALT;3'-azido-3'-deoxythymidine B-D-*glucuronide sodiu;3'-AZIDO-3'-DEOXYTHYMIDINE B-D-GLUCURONIDE, SODIUM SALT;3'-AZIDO-3'-DEOXYTHYMIDINE O-D-GLUCURONIDE SODIUM SALT;Zidovudine Glucuronide
14 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • 100MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberGCN0000077
  • Product description3'-AZIDO-3'-DEOXYTHYMIDINE BETA-D-GLUCURONIDE, SODIUM SALT 95.00%
  • Packaging10MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberGCN0000077
  • Product description3'-AZIDO-3'-DEOXYTHYMIDINE BETA-D-GLUCURONIDE, SODIUM SALT 95.00%
  • Packaging100MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3806
  • Product description3'-Azido-3'-deoxythymidineβ-D-glucuronide(sodiumsalt)
  • Packaging1mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3806
  • Product description3'-Azido-3'-deoxythymidineβ-D-glucuronide(sodiumsalt)
  • Packaging5mg
  • Price$171
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3806
  • Product description3'-Azido-3'-deoxythymidineβ-D-glucuronide(sodiumsalt)
  • Packaging10mg
  • Price$292
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNA06316
  • Product description3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt
  • Packaging2mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNA06316
  • Product description3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt
  • Packaging5mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNA06316
  • Product description3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt
  • Packaging10mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNA06316
  • Product description3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt
  • Packaging25mg
  • Price$485
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNA06316
  • Product description3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt
  • Packaging50mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18679
  • Product description3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt) ≥95%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18679
  • Product description3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt) ≥95%
  • Packaging5mg
  • Price$151
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18679
  • Product description3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt) ≥95%
  • Packaging10mg
  • Price$258
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberA825050
  • Product description3''-Azido-3''-deoxythymidineβ-D-glucuronide,SodiumSalt
  • Packaging25mg
  • Price$460
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation GCN0000077 3'-AZIDO-3'-DEOXYTHYMIDINE BETA-D-GLUCURONIDE, SODIUM SALT 95.00% 10MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation GCN0000077 3'-AZIDO-3'-DEOXYTHYMIDINE BETA-D-GLUCURONIDE, SODIUM SALT 95.00% 100MG $1871.1 2021-12-16 Buy
ApexBio Technology C3806 3'-Azido-3'-deoxythymidineβ-D-glucuronide(sodiumsalt) 1mg $68 2021-12-16 Buy
ApexBio Technology C3806 3'-Azido-3'-deoxythymidineβ-D-glucuronide(sodiumsalt) 5mg $171 2021-12-16 Buy
ApexBio Technology C3806 3'-Azido-3'-deoxythymidineβ-D-glucuronide(sodiumsalt) 10mg $292 2021-12-16 Buy
Biosynth Carbosynth NA06316 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt 2mg $95 2021-12-16 Buy
Biosynth Carbosynth NA06316 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt 5mg $135 2021-12-16 Buy
Biosynth Carbosynth NA06316 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt 10mg $200 2021-12-16 Buy
Biosynth Carbosynth NA06316 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt 25mg $485 2021-12-16 Buy
Biosynth Carbosynth NA06316 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt 50mg $950 2021-12-16 Buy
Cayman Chemical 18679 3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt) ≥95% 1mg $62 2024-03-01 Buy
Cayman Chemical 18679 3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt) ≥95% 5mg $151 2024-03-01 Buy
Cayman Chemical 18679 3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt) ≥95% 10mg $258 2024-03-01 Buy
TRC A825050 3''-Azido-3''-deoxythymidineβ-D-glucuronide,SodiumSalt 25mg $460 2021-12-16 Buy

Properties

Melting point :158-163°C
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :DMSO (Slightly, Heated, Sonicated), Methanol (Very Slightly, Heated), Water (Slightly)
form :Solid
color :White to Light Yellow
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

3'-Azido-3'-deoxythymidine β-D-glucuronide is a metabolite of the nucleoside reverse transcriptase inhibitor, zidovudine , formed by direct conjugation by UDP-glucuronosyltransferase 2B7. The azido group of both zidovudine and its glucuronide metabolite can be reduced to an amino group by cytochrome P450 (CYP)3A, CYP2A6, or CYP2B1, forming 3’-amino-3’-deoxythymidine (AMT) and AMT glucuronide, respectively. Several compounds, including rifampicin , valproic acid , fluconazole , and efavirenz are known to interfere with zidovudine glucuronidation in vitro in human liver microsomes. Formation of AMT, which is 5-7-fold more toxic than the parent drug, is thought to be enhanced through inhibition of zidovudine glucuronidation.

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