2-Fluoro-4'-[[4-(4-pyridinylMethyl)-1-piperazinyl]Methyl]-α,α-bis(trifluoroMethyl)-[1,1'-biphenyl]-4-Methanol
![2-Fluoro-4'-[[4-(4-pyridinylMethyl)-1-piperazinyl]Methyl]-α,α-bis(trifluoroMethyl)-[1,1'-biphenyl]-4-Methanol price.](/CAS/GIF/1359164-11-6.gif)
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- $37 - $1140
- Product name: 2-Fluoro-4'-[[4-(4-pyridinylMethyl)-1-piperazinyl]Methyl]-α,α-bis(trifluoroMethyl)-[1,1'-biphenyl]-4-Methanol
- CAS: 1359164-11-6
- MF: C26H24F7N3O
- MW: 527.48
- EINECS:
- MDL Number:MFCD25563263
- Synonyms:2-Fluoro-4'-[[4-(4-pyridinylMethyl)-1-piperazinyl]Methyl]-α,α-bis(trifluoroMethyl)-[1,1'-biphenyl]-4-Methanol;SR-2211;2-Fluoro-4'-[[4-(4-pyridinylMethyl)-1-piperazinyl]Methyl]-α,α-bis(trifluoroMethyl)-[1,1'-biphenyl]-4-Methanol (SR 2211);[1,1'-Biphenyl]-4-methanol, 2-fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-α,α-bis(trifluoromethyl)-;2-Fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-a,a-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol;SR-2211,SR2211
13 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Tocris
- TRC
Package
- 5mg
- 10
- 1mg
- 50
- 10mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product numberSYN5040
- Product descriptionSR-2211
- Packaging10mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5040
- Product descriptionSR-2211
- Packaging100mg
- Price$1140
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5743
- Product descriptionSR2211
- Packaging5mg
- Price$151
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5743
- Product descriptionSR2211
- Packaging10mg
- Price$182
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11972
- Product descriptionSR 2211 ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11972
- Product descriptionSR 2211 ≥98%
- Packaging5mg
- Price$134
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11972
- Product descriptionSR 2211 ≥98%
- Packaging10mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0013508
- Product descriptionSR2211 98.59%
- Packaging5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0013508
- Product descriptionSR2211 98.59%
- Packaging10mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number4869
- Product descriptionSR2211 ≥98%(HPLC)
- Packaging10
- Price$223
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number4869
- Product descriptionSR2211 ≥98%(HPLC)
- Packaging50
- Price$926
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberF595930
- Product description2-Fluoro-4''-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-α,α-bis(trifluoromethyl)-[1,1''-biphenyl]-4-methanol
- Packaging5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberF595930
- Product description2-Fluoro-4''-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-α,α-bis(trifluoromethyl)-[1,1''-biphenyl]-4-methanol
- Packaging50mg
- Price$1050
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5040 | SR-2211 | 10mg | $225 | 2021-12-16 | Buy |
| AK Scientific | SYN5040 | SR-2211 | 100mg | $1140 | 2021-12-16 | Buy |
| ApexBio Technology | B5743 | SR2211 | 5mg | $151 | 2021-12-16 | Buy |
| ApexBio Technology | B5743 | SR2211 | 10mg | $182 | 2021-12-16 | Buy |
| Cayman Chemical | 11972 | SR 2211 ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 11972 | SR 2211 ≥98% | 5mg | $134 | 2024-03-01 | Buy |
| Cayman Chemical | 11972 | SR 2211 ≥98% | 10mg | $161 | 2024-03-01 | Buy |
| ChemScene | CS-0013508 | SR2211 98.59% | 5mg | $130 | 2021-12-16 | Buy |
| ChemScene | CS-0013508 | SR2211 98.59% | 10mg | $230 | 2021-12-16 | Buy |
| Tocris | 4869 | SR2211 ≥98%(HPLC) | 10 | $223 | 2021-12-16 | Buy |
| Tocris | 4869 | SR2211 ≥98%(HPLC) | 50 | $926 | 2021-12-16 | Buy |
| TRC | F595930 | 2-Fluoro-4''-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-α,α-bis(trifluoromethyl)-[1,1''-biphenyl]-4-methanol | 5mg | $130 | 2021-12-16 | Buy |
| TRC | F595930 | 2-Fluoro-4''-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-α,α-bis(trifluoromethyl)-[1,1''-biphenyl]-4-methanol | 50mg | $1050 | 2021-12-16 | Buy |
Properties
Boiling point :552.4±50.0 °C(Predicted)
Density :1.358±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl
form :Powder
pka :8.85±0.19(Predicted)
color :Off-white to light brown
Density :1.358±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl
form :Powder
pka :8.85±0.19(Predicted)
color :Off-white to light brown
Safety Information
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| Signal word: | Danger | ||||||||||||||||
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Description
Retinoic acid receptor-related nuclear receptor γ (RORγ) plays a central role in T cell differentiation, particularly in the differentiation of pro-inflammatory TH17 cells, which are implicated in autoimmune diseases like multiple sclerosis and rheumatoid arthritis. SR 2211 selectively binds RORγ (Ki = 105 nM), acting as an inverse agonist of constitutive in vitro RORγ activity (IC50 = 320 nM). It has minimal effects on RORα, LXRα, and FXR activities. SR 2211 significantly inhibits gene expression of IL-17 and IL-23 receptor in activated EL-4 mouse T lymphocytes when given at 5 μM.More related product prices
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