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ChemicalBook >> CAS DataBase List >> 4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidinehydrochloride

4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidinehydrochloride

4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidinehydrochloride price.
  • $100 - $5103
  • Product name: 4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidinehydrochloride
  • CAS: 136647-02-4
  • MF: C29H35NO2.HCl
  • MW: 466
  • EINECS:
  • MDL Number:MFCD16875438
  • Synonyms:4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidinehydrochloride;UK 78282 hydrochloride;4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-pi;4-(3,3-diphenylpropyl)-1-(3-(4-Methoxyphenyl)propyl)piperidine h;4-((Benzhydryloxy)Methyl)-1-(3-(4-Methoxyphenyl)propyl)piperidine hydrochloride;4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidine monohydrochloride;UK-78282 monohydrochloride;4-(3,3-diphenylpropyl)-1-(3-(4-methoxyphenyl)propyl)piperidine hydrochloride
10 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 50
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 250mg
  • ManufacturerAK Scientific
  • Product numberX6456
  • Product description4-((Benzhydryloxy)methyl)-1-(3-(4-methoxyphenyl)-propyl)piperidinehydrochloride
  • Packaging250mg
  • Price$5103
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008852
  • Product descriptionUK-78282 MONOHYDROCHLORIDE 95.00%
  • Packaging25MG
  • Price$1042.97
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7507
  • Product descriptionUK78282hydrochloride
  • Packaging50mg
  • Price$1385
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number096998
  • Product description4-((Benzhydryloxy)methyl)-1-(3-(4-methoxyphenyl)-propyl)piperidine hydrochloride 95+%
  • Packaging250mg
  • Price$3743
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberU3885
  • Product descriptionUK-78282 monohydrochloride ≥98% (HPLC)
  • Packaging5mg
  • Price$180
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number3829
  • Product descriptionUK78282hydrochloride ≥99%(HPLC)
  • Packaging10
  • Price$221
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3829
  • Product descriptionUK78282hydrochloride ≥99%(HPLC)
  • Packaging50
  • Price$924
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberU700625
  • Product descriptionUK78282Hydrochloride
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberU700625
  • Product descriptionUK78282Hydrochloride
  • Packaging25mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number257021
  • Product descriptionUK 78282 hydrochloride
  • Packaging10mg
  • Price$502
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X6456 4-((Benzhydryloxy)methyl)-1-(3-(4-methoxyphenyl)-propyl)piperidinehydrochloride 250mg $5103 2021-12-16 Buy
American Custom Chemicals Corporation API0008852 UK-78282 MONOHYDROCHLORIDE 95.00% 25MG $1042.97 2021-12-16 Buy
ApexBio Technology B7507 UK78282hydrochloride 50mg $1385 2021-12-16 Buy
Matrix Scientific 096998 4-((Benzhydryloxy)methyl)-1-(3-(4-methoxyphenyl)-propyl)piperidine hydrochloride 95+% 250mg $3743 2021-12-16 Buy
Sigma-Aldrich U3885 UK-78282 monohydrochloride ≥98% (HPLC) 5mg $180 2024-03-01 Buy
Tocris 3829 UK78282hydrochloride ≥99%(HPLC) 10 $221 2021-12-16 Buy
Tocris 3829 UK78282hydrochloride ≥99%(HPLC) 50 $924 2021-12-16 Buy
TRC U700625 UK78282Hydrochloride 5mg $100 2021-12-16 Buy
TRC U700625 UK78282Hydrochloride 25mg $450 2021-12-16 Buy
Usbiological 257021 UK 78282 hydrochloride 10mg $502 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO: >10mg/mL
form :solid
color :white to off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

UK-78282 blocks Kv1.3 and Kv1.4, which are members of the Shaker family of voltage-gated potassium channels. Kv1.3 is expressed in brain and effector memory T (Tem) cells, and Kv1.4 is expressed in brain. Both channels are involved in setting the membrane potential of neurons. Kv1.3 also maintains the membrane potential for T memory cells and is up-regulated upon T cell activation, contributing to multiple immune processes and disorders. Blockers of Kv1.3 have long been sought for therapeutic benefit, and they are also valuable tools for studying the immune system. Selective blockers of Kv1.4 are desired, as there are few if any currently available. UK-78282 is valuable for immune system studies, where the absence of Kv1.4 makes it functionally selective for Kv1.3, and it has shown suppression of T cell activation. UK-78282 is also valuable for the study of Kv1.4 function.