N,N-DIMETHYL-(3R,4AR,5S,6AS,10S,10AR,10BS)-5-(ACETYLOXY)-3-ETHENYLDODECAHYDRO-10,10B-DIHYDROXY-3,4A,7,7,10A-PENTAMETHYL-1-OXO-1H-NAPHTHO[2,1-B]PYRAN-6-YL ESTER B-ALANINE HYDROCHLORIDE
![N,N-DIMETHYL-(3R,4AR,5S,6AS,10S,10AR,10BS)-5-(ACETYLOXY)-3-ETHENYLDODECAHYDRO-10,10B-DIHYDROXY-3,4A,7,7,10A-PENTAMETHYL-1-OXO-1H-NAPHTHO[2,1-B]PYRAN-6-YL ESTER B-ALANINE HYDROCHLORIDE price.](/CAS/GIF/138605-00-2.gif)
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- $32 - $915
- Product name: N,N-DIMETHYL-(3R,4AR,5S,6AS,10S,10AR,10BS)-5-(ACETYLOXY)-3-ETHENYLDODECAHYDRO-10,10B-DIHYDROXY-3,4A,7,7,10A-PENTAMETHYL-1-OXO-1H-NAPHTHO[2,1-B]PYRAN-6-YL ESTER B-ALANINE HYDROCHLORIDE
- CAS: 138605-00-2
- MF: C27H44ClNO8
- MW: 546.1
- EINECS:
- MDL Number:MFCD00236421
- Synonyms:N,N-DIMETHYL-(3R,4AR,5S,6AS,10S,10AR,10BS)-5-(ACETYLOXY)-3-ETHENYLDODECAHYDRO-10,10B-DIHYDROXY-3,4A,7,7,10A-PENTAMETHYL-1-OXO-1H-NAPHTHO[2,1-B]PYRAN-6-YL ESTER B-ALANINE HYDROCHLORIDE;NKH 477;(3r-(3-alpha,4a-beta,5-beta,6-beta,6a-alpha,10-alpha,10a-beta,10b-alpha))-id ;N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester b-Alanine hydrochloride;Forskolin, NKH477 ;beta-alanine,n,n-dimethyl-,5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydrox ;colforsindapropatehydrochloride ;N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester beta-alanine hydrochloride
15 prices
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Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1MG
- 5mg
- 10mg
- 25mg
- 10
- 50mg
- ManufacturerAK Scientific
- Product numberX3860
- Product descriptionNKH 477
- Packaging5mg
- Price$202
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0015171
- Product descriptionCOLFORSIN DAROPATE HYDROCHLORIDE 95.00%
- Packaging1MG
- Price$128.1
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0015171
- Product descriptionCOLFORSIN DAROPATE HYDROCHLORIDE 95.00%
- Packaging5MG
- Price$496.25
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6802
- Product descriptionNKH 477
- Packaging1mg
- Price$197
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11214
- Product descriptionNKH477 (hydrochloride) ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11214
- Product descriptionNKH477 (hydrochloride) ≥95%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11214
- Product descriptionNKH477 (hydrochloride) ≥95%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0025284
- Product descriptionNKH 477 ≥99.0%
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0025284
- Product descriptionNKH 477 ≥99.0%
- Packaging50mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberN3290
- Product descriptionNKH 477 ≥98% (HPLC), powder
- Packaging5mg
- Price$147
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberN3290
- Product descriptionNKH 477 ≥98% (HPLC), powder
- Packaging25mg
- Price$581
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number1603
- Product descriptionNKH 477 ≥98%(HPLC)
- Packaging10
- Price$219
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number1603
- Product descriptionNKH 477 ≥98%(HPLC)
- Packaging50
- Price$915
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberN605000
- Product descriptionNKH 477
- Packaging50mg
- Price$865
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number256002
- Product descriptionNKH 477
- Packaging10mg
- Price$502
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X3860 | NKH 477 | 5mg | $202 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0015171 | COLFORSIN DAROPATE HYDROCHLORIDE 95.00% | 1MG | $128.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0015171 | COLFORSIN DAROPATE HYDROCHLORIDE 95.00% | 5MG | $496.25 | 2021-12-16 | Buy |
| ApexBio Technology | B6802 | NKH 477 | 1mg | $197 | 2021-12-16 | Buy |
| Cayman Chemical | 11214 | NKH477 (hydrochloride) ≥95% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 11214 | NKH477 (hydrochloride) ≥95% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 11214 | NKH477 (hydrochloride) ≥95% | 10mg | $184 | 2024-03-01 | Buy |
| ChemScene | CS-0025284 | NKH 477 ≥99.0% | 5mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-0025284 | NKH 477 ≥99.0% | 50mg | $650 | 2021-12-16 | Buy |
| Sigma-Aldrich | N3290 | NKH 477 ≥98% (HPLC), powder | 5mg | $147 | 2024-03-01 | Buy |
| Sigma-Aldrich | N3290 | NKH 477 ≥98% (HPLC), powder | 25mg | $581 | 2024-03-01 | Buy |
| Tocris | 1603 | NKH 477 ≥98%(HPLC) | 10 | $219 | 2021-12-16 | Buy |
| Tocris | 1603 | NKH 477 ≥98%(HPLC) | 50 | $915 | 2021-12-16 | Buy |
| TRC | N605000 | NKH 477 | 50mg | $865 | 2021-12-16 | Buy |
| Usbiological | 256002 | NKH 477 | 10mg | $502 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C
solubility :H2O: soluble3mg/mL, clear to slightly hazy (warmed)
form :White solid
color :white to beige
Water Solubility :Soluble to 40 mM in water
solubility :H2O: soluble3mg/mL, clear to slightly hazy (warmed)
form :White solid
color :white to beige
Water Solubility :Soluble to 40 mM in water
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Forskolin is a potent activator of adenylyl cyclase, but it is sparingly soluble in aqueous solutions. NKH477 is a water-soluble analog of forskolin which has both inotropic and vasodilator effects when administered intravenously. Like forskolin, NKH477 activates adenylyl cyclases without altering the activity of phosphodiesterases or sodium/potassium ATPases. This compound stimulates cardiac (type V) adenylyl cyclase more potently than other isoforms. NKH477 relaxes guinea pig tracheal smooth muscle precontracted with histamine with an EC50 value of 32.6 nM.Related product price
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