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ChemicalBook >> CAS DataBase List >> glucagon receptor antagonists-4

glucagon receptor antagonists-4

glucagon receptor antagonists-4 price.
  • $32 - $2520
  • Product name: glucagon receptor antagonists-4
  • CAS: 1393124-08-7
  • MF: C26H28F3N3O4
  • MW: 503.51
  • EINECS:
  • MDL Number:MFCD30343861
  • Synonyms:glucagon receptor antagonists-4;N-{4-[(1S)-1-{3,5-Dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy}butyl]benzoyl}-β-alanine;lucagon receptor antagonists-4;Glucagon Receptor Antagonist 4;GCGR-IN-17;PF06291874;PF-06291874;PF 06291874;PF6291874;CS-2641
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  • AK Scientific
  • Apolloscientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
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  • ManufacturerAK Scientific
  • Product number8522DP
  • Product descriptionGlucagonreceptorantagonists-4
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product number8522DP
  • Product descriptionGlucagonreceptorantagonists-4
  • Packaging5mg
  • Price$201
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product number8522DP
  • Product descriptionGlucagonreceptorantagonists-4
  • Packaging10mg
  • Price$286
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product number8522DP
  • Product descriptionGlucagonreceptorantagonists-4
  • Packaging25mg
  • Price$522
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBISN0020
  • Product descriptionGlucagonReceptorAntagonists-4 98%
  • Packaging1mg
  • Price$225
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBISN0020
  • Product descriptionGlucagonReceptorAntagonists-4 98%
  • Packaging5mg
  • Price$508
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBISN0020
  • Product descriptionGlucagonReceptorAntagonists-4 98%
  • Packaging10mg
  • Price$754
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number22164
  • Product descriptionGlucagon Receptor Antagonist 4
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number22164
  • Product descriptionGlucagon Receptor Antagonist 4
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number22164
  • Product descriptionGlucagon Receptor Antagonist 4
  • Packaging10mg
  • Price$169
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number22164
  • Product descriptionGlucagon Receptor Antagonist 4
  • Packaging25mg
  • Price$381
  • Updated2024-03-01
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  • ManufacturerChemScene
  • Product numberCS-5665
  • Product descriptionPF-06291874 99.70%
  • Packaging1mg
  • Price$180
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-5665
  • Product descriptionPF-06291874 99.70%
  • Packaging5mg
  • Price$420
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-5665
  • Product descriptionPF-06291874 99.70%
  • Packaging10mg
  • Price$600
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-5665
  • Product descriptionPF-06291874 99.70%
  • Packaging50mg
  • Price$1800
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-5665
  • Product descriptionPF-06291874 99.70%
  • Packaging100mg
  • Price$2520
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8522DP Glucagonreceptorantagonists-4 1mg $133 2021-12-16 Buy
AK Scientific 8522DP Glucagonreceptorantagonists-4 5mg $201 2021-12-16 Buy
AK Scientific 8522DP Glucagonreceptorantagonists-4 10mg $286 2021-12-16 Buy
AK Scientific 8522DP Glucagonreceptorantagonists-4 25mg $522 2021-12-16 Buy
Apolloscientific BISN0020 GlucagonReceptorAntagonists-4 98% 1mg $225 2021-12-16 Buy
Apolloscientific BISN0020 GlucagonReceptorAntagonists-4 98% 5mg $508 2021-12-16 Buy
Apolloscientific BISN0020 GlucagonReceptorAntagonists-4 98% 10mg $754 2021-12-16 Buy
Cayman Chemical 22164 Glucagon Receptor Antagonist 4 1mg $32 2024-03-01 Buy
Cayman Chemical 22164 Glucagon Receptor Antagonist 4 5mg $93 2024-03-01 Buy
Cayman Chemical 22164 Glucagon Receptor Antagonist 4 10mg $169 2024-03-01 Buy
Cayman Chemical 22164 Glucagon Receptor Antagonist 4 25mg $381 2024-03-01 Buy
ChemScene CS-5665 PF-06291874 99.70% 1mg $180 2021-12-16 Buy
ChemScene CS-5665 PF-06291874 99.70% 5mg $420 2021-12-16 Buy
ChemScene CS-5665 PF-06291874 99.70% 10mg $600 2021-12-16 Buy
ChemScene CS-5665 PF-06291874 99.70% 50mg $1800 2021-12-16 Buy
ChemScene CS-5665 PF-06291874 99.70% 100mg $2520 2021-12-16 Buy

Properties

Boiling point :675.0±55.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50mg/mL; DMSO: 50mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL; Ethanol: 0.5mg/mL
form :A crystalline solid
pka :4.28±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PF-06291874 is a novel and potent glucagon receptor antagonist for the potential treatment of diabetes mellitus. PF-06291874, has a lower molcular weight and lipophilicity than historical glucagon receptor antagonists, resulting in excellent selectivity in broad-panel screening, lower cytotoxicity, and excellent overall in vivo safety in early pre-clinical testing.