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ChemicalBook >> CAS DataBase List >> 14,15-LEUKOTRIENE E4

14,15-LEUKOTRIENE E4

14,15-LEUKOTRIENE E4 price.
  • $132 - $469
  • Product name: 14,15-LEUKOTRIENE E4
  • CAS: 1000852-57-2
  • MF: C23H37NO5S
  • MW: 439.61
  • EINECS:
  • MDL Number:MFCD03844880
  • Synonyms:14,15-LEUKOTRIENE E4;14,15-Leukotriene E4;JLJNENVYAVKECZ-HRXVJLLUSA-N;14,15-Leukotriene E4 (Eoxin-E4);15s-Hydroxy-14r-(S-Cysteinyl)-5z,8z,10e,12e- Eicosatetraenoic Acid;5,8,10,12-Eicosatetraenoic acid, 14-[[(2R)-2-amino-2-carboxyethyl]thio]-15-hydroxy-, (5Z,8Z,10E,12E,14R,15S)-;Eoxin E4
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • Cayman Chemical
  • TRC
Package
  • 25μg
  • 50μg
  • 100μg
  • ManufacturerCayman Chemical
  • Product number10011362
  • Product description14,15-Leukotriene E4 ≥97%
  • Packaging100μg
  • Price$469
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011362
  • Product description14,15-Leukotriene E4 ≥97%
  • Packaging50μg
  • Price$249
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011362
  • Product description14,15-Leukotriene E4 ≥97%
  • Packaging25μg
  • Price$132
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberL330370
  • Product description14,15-LeukotrieneE4
  • Packaging50μg
  • Price$230
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 10011362 14,15-Leukotriene E4 ≥97% 100μg $469 2024-03-01 Buy
Cayman Chemical 10011362 14,15-Leukotriene E4 ≥97% 50μg $249 2024-03-01 Buy
Cayman Chemical 10011362 14,15-Leukotriene E4 ≥97% 25μg $132 2024-03-01 Buy
TRC L330370 14,15-LeukotrieneE4 50μg $230 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: > 50mg/ml; DMSO: > 50mg/ml; Ethanol: > 50mg/ml; PBS (pH 7.2): > 100μg/ml
form :Liquid.

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P307+P311 IF exposed: call a POISON CENTER or doctor/physician.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway. 14,15-LTE4 is a metabolite of 14,15-LTC4 and 14,15-LTD4, an alternate class of LTs made by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. These metabolites are classified as eoxins because they are formed mostly by eosinophils. Mast cells and nasal polyps can synthesize 14,15-LTC4 as well, however metabolism to 14,15-LTE4 in these cells and tissue has not been documented. 14,15-LTE4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency compared LTC4, but approximately 100-fold greater potency than histamine.

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