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ChemicalBook >> CAS DataBase List >> N-Butyl-1-deoxygalactonojirimycin

N-Butyl-1-deoxygalactonojirimycin

N-Butyl-1-deoxygalactonojirimycin price.
  • $44 - $1533
  • Product name: N-Butyl-1-deoxygalactonojirimycin
  • CAS: 141206-42-0
  • MF: C10H21NO4
  • MW: 219.28
  • EINECS:
  • MDL Number:MFCD00269939
  • Synonyms:N-Butyl-1-deoxygalactonojirimycin;(2R,3S,4R,5S)-1-(But-1-yl)-2-(hydroxymethyl)piperidine-3,4,5-triol;N-(But-1-yl)deoxygalactonojirimycin, (2R,3S,4R,5S)-1-(But-1-yl)-2-(hydroxymethyl)-3,4,5-trihydroxypiperidine;(2R,3S,4R,5S)-1-Butyl-2-(hydroxyMethyl)-3,4,5-piperidinetriol;Lucerastat;ACT-434964;Lucerastat (N-Butyldeoxygalactonojirimycin;OGT-923)
14 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • SynQuest Laboratories
  • TRC
Package
  • 500μg
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number3664CC
  • Product descriptionLucerastat
  • Packaging5mg
  • Price$295
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000001
  • Product descriptionN-(N-BUTYL)DEOXYGALACTONOJIRIMYCIN 95.00%
  • Packaging5MG
  • Price$476.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMB04497
  • Product descriptionN-Butyldeoxygalactonojirimycin
  • Packaging1mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMB04497
  • Product descriptionN-Butyldeoxygalactonojirimycin
  • Packaging2mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMB04497
  • Product descriptionN-Butyldeoxygalactonojirimycin
  • Packaging5mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMB04497
  • Product descriptionN-Butyldeoxygalactonojirimycin
  • Packaging10mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMB04497
  • Product descriptionN-Butyldeoxygalactonojirimycin
  • Packaging25mg
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19520
  • Product descriptionN-(n-Butyl)deoxygalactonojirimycin ≥95%
  • Packaging500μg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19520
  • Product descriptionN-(n-Butyl)deoxygalactonojirimycin ≥95%
  • Packaging1mg
  • Price$78
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19520
  • Product descriptionN-(n-Butyl)deoxygalactonojirimycin ≥95%
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerSynQuest Laboratories
  • Product number4H05-1-01
  • Product description(2R,3S,4R,5S)-1-(But-1-yl)-2-(hydroxymethyl)piperidine-3,4,5-triol
  • Packaging1mg
  • Price$272
  • Updated2021-12-16
  • Buy
  • ManufacturerSynQuest Laboratories
  • Product number4H05-1-01
  • Product description(2R,3S,4R,5S)-1-(But-1-yl)-2-(hydroxymethyl)piperidine-3,4,5-triol
  • Packaging5mg
  • Price$456
  • Updated2021-12-16
  • Buy
  • ManufacturerSynQuest Laboratories
  • Product number4H05-1-01
  • Product description(2R,3S,4R,5S)-1-(But-1-yl)-2-(hydroxymethyl)piperidine-3,4,5-triol
  • Packaging25mg
  • Price$1533
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB690500
  • Product descriptionN-(n-Butyl)deoxygalactonojirimycin
  • Packaging25mg
  • Price$725
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3664CC Lucerastat 5mg $295 2021-12-16 Buy
American Custom Chemicals Corporation INB0000001 N-(N-BUTYL)DEOXYGALACTONOJIRIMYCIN 95.00% 5MG $476.3 2021-12-16 Buy
Biosynth Carbosynth MB04497 N-Butyldeoxygalactonojirimycin 1mg $100 2021-12-16 Buy
Biosynth Carbosynth MB04497 N-Butyldeoxygalactonojirimycin 2mg $150 2021-12-16 Buy
Biosynth Carbosynth MB04497 N-Butyldeoxygalactonojirimycin 5mg $300 2021-12-16 Buy
Biosynth Carbosynth MB04497 N-Butyldeoxygalactonojirimycin 10mg $500 2021-12-16 Buy
Biosynth Carbosynth MB04497 N-Butyldeoxygalactonojirimycin 25mg $1100 2021-12-16 Buy
Cayman Chemical 19520 N-(n-Butyl)deoxygalactonojirimycin ≥95% 500μg $44 2024-03-01 Buy
Cayman Chemical 19520 N-(n-Butyl)deoxygalactonojirimycin ≥95% 1mg $78 2024-03-01 Buy
Cayman Chemical 19520 N-(n-Butyl)deoxygalactonojirimycin ≥95% 5mg $193 2024-03-01 Buy
SynQuest Laboratories 4H05-1-01 (2R,3S,4R,5S)-1-(But-1-yl)-2-(hydroxymethyl)piperidine-3,4,5-triol 1mg $272 2021-12-16 Buy
SynQuest Laboratories 4H05-1-01 (2R,3S,4R,5S)-1-(But-1-yl)-2-(hydroxymethyl)piperidine-3,4,5-triol 5mg $456 2021-12-16 Buy
SynQuest Laboratories 4H05-1-01 (2R,3S,4R,5S)-1-(But-1-yl)-2-(hydroxymethyl)piperidine-3,4,5-triol 25mg $1533 2021-12-16 Buy
TRC B690500 N-(n-Butyl)deoxygalactonojirimycin 25mg $725 2021-12-16 Buy

Properties

Melting point :123-124°C
Boiling point :394.7±42.0 °C(Predicted)
Density :1.234±0.06 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMF: 20 mg/mL; DMSO: 30 mg/mL; Ethanol: 5 mg/mL; PBS (pH 7.2): 10 mg/mL
form :A crystalline solid
pka :13.72±0.70(Predicted)
color :White to yellow
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

N-(n-Butyl)deoxygalactonojirimycin is an inhibitor of α-D-galactosidase. It has also been shown to prevent glucosylceramide biosynthesis both in vitro and in mouse models of lysosome storage disorders by inhibiting the ceramide-specific glucosyltransferase, UDP-glucose ceramide glucosyltransferase (IC50 = 41.4 μM) without affecting α-glucosidase I and II or β-glucocerebrosidase (IC50s > 1 mM). This compound has been used to sensitize cultured chronic lymphocytic leukemia cells to the chemotherapeutic agents cladribine , chlorambucil, and fludarabine .

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