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ChemicalBook >> CAS DataBase List >> N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N′-(2-pyridinylmethyl)-urea

N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N′-(2-pyridinylmethyl)-urea

N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N′-(2-pyridinylmethyl)-urea price.
  • $32 - $576
  • Product name: N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N′-(2-pyridinylmethyl)-urea
  • CAS: 1414963-82-8
  • MF: C13H11N5O3
  • MW: 285.26
  • EINECS:
  • MDL Number:MFCD28009512
  • Synonyms:N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N′-(2-pyridinylmethyl)-urea;NK 252;NK252;Urea, N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)-;NK-252 >=98% (HPLC);NK-252,NK252,NK 252,inhibit,Inhibitor,Keap1-Nrf2;1-(5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl)-3-(pyridin-2-ylmethyl)urea
Price17 Properties Safety Information Description
17 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 2.5mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number9739DU
  • Product descriptionCID71618700
  • Packaging10mg
  • Price$268
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA278611
  • Product descriptionNK-252 98+%
  • Packaging100mg
  • Price$570
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5715
  • Product descriptionNK252
  • Packaging5mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5715
  • Product descriptionNK252
  • Packaging10mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5715
  • Product descriptionNK252
  • Packaging25mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19131
  • Product descriptionNK 252 ≥98%
  • Packaging25mg
  • Price$343
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19131
  • Product descriptionNK 252 ≥98%
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19131
  • Product descriptionNK 252 ≥98%
  • Packaging5mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19131
  • Product descriptionNK 252 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5458
  • Product descriptionNK-252 99.96%
  • Packaging100mg
  • Price$576
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5458
  • Product descriptionNK-252 99.96%
  • Packaging50mg
  • Price$312
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5458
  • Product descriptionNK-252 99.96%
  • Packaging25mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5458
  • Product descriptionNK-252 99.96%
  • Packaging10mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5458
  • Product descriptionNK-252 99.96%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0944
  • Product descriptionNK-252 ≥98% (HPLC)
  • Packaging5mg
  • Price$85.3
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0944
  • Product descriptionNK-252 ≥98% (HPLC)
  • Packaging25mg
  • Price$335
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9739DU CID71618700 10mg $268 2021-12-16 Buy
Ambeed A278611 NK-252 98+% 100mg $570 2021-12-16 Buy
ApexBio Technology C5715 NK252 5mg $96 2021-12-16 Buy
ApexBio Technology C5715 NK252 10mg $173 2021-12-16 Buy
ApexBio Technology C5715 NK252 25mg $390 2021-12-16 Buy
Cayman Chemical 19131 NK 252 ≥98% 25mg $343 2024-03-01 Buy
Cayman Chemical 19131 NK 252 ≥98% 10mg $153 2024-03-01 Buy
Cayman Chemical 19131 NK 252 ≥98% 5mg $86 2024-03-01 Buy
Cayman Chemical 19131 NK 252 ≥98% 1mg $32 2024-03-01 Buy
ChemScene CS-5458 NK-252 99.96% 100mg $576 2021-12-16 Buy
ChemScene CS-5458 NK-252 99.96% 50mg $312 2021-12-16 Buy
ChemScene CS-5458 NK-252 99.96% 25mg $180 2021-12-16 Buy
ChemScene CS-5458 NK-252 99.96% 10mg $84 2021-12-16 Buy
ChemScene CS-5458 NK-252 99.96% 5mg $60 2021-12-16 Buy
Sigma-Aldrich SML0944 NK-252 ≥98% (HPLC) 5mg $85.3 2024-03-01 Buy
Sigma-Aldrich SML0944 NK-252 ≥98% (HPLC) 25mg $335 2024-03-01 Buy
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Properties

Density :1.408±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :11.50±0.70(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NK 252 is a Nrf2 activator that interacts directly with the domain containing the Nrf2-binding site of Keap1. At 1.36 μM, it is reported to activate the NQO1-antioxidant response element in a luciferase reporter gene assay two-fold above background. NK 252 has been shown to downregulate the expression of fibrogenic genes, producing antifibrotic effects in a rat model of nonalcoholic steatohepatitis.

Suppliers and manufacturers

ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
Career Henan Chemica Co
Nantong HI-FUTURE Biology Co., Ltd.
Aladdin Scientific BOC Sciences MedChemexpress LLC ShangHai Caerulum Pharma Discovery Co., Ltd. Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd.