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ChemicalBook >> CAS DataBase List >> 2,1,3-Benzoxadiazol-5-aMine, N-(3-chloro-5-fluorophenyl)-4-nitro-

2,1,3-Benzoxadiazol-5-aMine, N-(3-chloro-5-fluorophenyl)-4-nitro-

2,1,3-Benzoxadiazol-5-aMine, N-(3-chloro-5-fluorophenyl)-4-nitro- price.
  • $87 - $870
  • Product name: 2,1,3-Benzoxadiazol-5-aMine, N-(3-chloro-5-fluorophenyl)-4-nitro-
  • CAS: 1422955-31-4
  • MF: C12H6ClFN4O3
  • MW: 308.6524432
  • EINECS:
  • MDL Number:MFCD25371546
  • Synonyms:2,1,3-Benzoxadiazol-5-aMine, N-(3-chloro-5-fluorophenyl)-4-nitro-;HIF-C2;HIF-2 Antagonist 2;N-(3-Chloro-5-fluorophenyl)-4-nitrobenzo[c][1,2,5]oxadiazol-5-amine;HIF-2 inhibitor 2;HIF Inhibitor VII - Calbiochem;TC-S 7009;N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
13 prices
Selected condition:
Brand
  • AK Scientific
  • Axon Medchem
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25
  • 2x5mg
  • 5
  • 25mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number1783DU
  • Product descriptionN-(3-Chloro-5-Fluorophenyl)-4-Nitro-2,1,3-Benzoxadiazol-5-Amine
  • Packaging1mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1783DU
  • Product descriptionN-(3-Chloro-5-Fluorophenyl)-4-Nitro-2,1,3-Benzoxadiazol-5-Amine
  • Packaging5mg
  • Price$191
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2034
  • Product descriptionHIF-2inhibitor2-Compound2 100%
  • Packaging2x5mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2034
  • Product descriptionHIF-2inhibitor2-Compound2 100%
  • Packaging25mg
  • Price$313.5
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0007949
  • Product descriptionTC-S7009 99.78%
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0883
  • Product descriptionHIF-2 Antagonist 2 ≥98% (HPLC)
  • Packaging5mg
  • Price$118
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number5.04379
  • Product descriptionHIF Inhibitor VII - Calbiochem
  • Packaging10MG
  • Price$265
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0883
  • Product descriptionHIF-2 Antagonist 2 ≥98% (HPLC)
  • Packaging25mg
  • Price$478
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number5243
  • Product descriptionTC-S7009 ≥99%(HPLC)
  • Packaging5
  • Price$87
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number5243
  • Product descriptionTC-S7009 ≥99%(HPLC)
  • Packaging25
  • Price$324
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC368260
  • Product descriptionN-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
  • Packaging25mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC368260
  • Product descriptionN-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
  • Packaging100mg
  • Price$870
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256859
  • Product descriptionTC-S 7009
  • Packaging10mg
  • Price$395
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1783DU N-(3-Chloro-5-Fluorophenyl)-4-Nitro-2,1,3-Benzoxadiazol-5-Amine 1mg $140 2021-12-16 Buy
AK Scientific 1783DU N-(3-Chloro-5-Fluorophenyl)-4-Nitro-2,1,3-Benzoxadiazol-5-Amine 5mg $191 2021-12-16 Buy
Axon Medchem Axon2034 HIF-2inhibitor2-Compound2 100% 2x5mg $154 2021-12-16 Buy
Axon Medchem Axon2034 HIF-2inhibitor2-Compound2 100% 25mg $313.5 2021-12-16 Buy
ChemScene CS-0007949 TC-S7009 99.78% 10mg $150 2021-12-16 Buy
Sigma-Aldrich SML0883 HIF-2 Antagonist 2 ≥98% (HPLC) 5mg $118 2024-03-01 Buy
Sigma-Aldrich 5.04379 HIF Inhibitor VII - Calbiochem 10MG $265 2024-03-01 Buy
Sigma-Aldrich SML0883 HIF-2 Antagonist 2 ≥98% (HPLC) 25mg $478 2024-03-01 Buy
Tocris 5243 TC-S7009 ≥99%(HPLC) 5 $87 2021-12-16 Buy
Tocris 5243 TC-S7009 ≥99%(HPLC) 25 $324 2021-12-16 Buy
TRC C368260 N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine 25mg $225 2021-12-16 Buy
TRC C368260 N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine 100mg $870 2021-12-16 Buy
Usbiological 256859 TC-S 7009 10mg $395 2021-12-16 Buy

Properties

Boiling point :430.2±55.0 °C(Predicted)
Density :1.652±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble15mg/mL, clear
form :Yellow powder
pka :-2.82±0.48(Predicted)
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

HIF-2α-I2 (1422955-31-4) is a potent and selective HIF-2α inhibitor, Kd=81 nM.1?Binds to the HIF-2α PAS-B domain2?and interferes with Hif-2α / ARNT heterodimerization reducing target gene expression in a cellular model1. Highly selective for HIF-2α displaying a >60-fold selectivity over HIF-1α.1,2

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