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ChemicalBook >> CAS DataBase List >> 7-AMino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyriMidine-6-carboxaMide

7-AMino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyriMidine-6-carboxaMide

7-AMino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyriMidine-6-carboxaMide price.
  • $32 - $5670
  • Product name: 7-AMino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyriMidine-6-carboxaMide
  • CAS: 142557-61-7
  • MF: C13H15N5O3
  • MW: 289.29
  • EINECS:
  • MDL Number:MFCD22683836
  • Synonyms:7-AMino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyriMidine-6-carboxaMide;7-AMino-1-cyclopropyl-3-ethyl-2,4-dioxopyrido[2,3-d]pyriMidine-6-carboxaMide;A-484954(A 484954);A 484954;7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxo-pyrido[2,3-d]pyrimidine-6-carboxamideddd;eEF2K Inhibitor, A-484954 ;7-Amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamid;Pyrido[2,3-d]pyrimidine-6-carboxamide, 7-amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxo-
Price31 Properties Safety Information Description
31 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 50
  • 10
  • 1mg
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • 100MG
  • 250mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product numberX5939
  • Product description7-amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide
  • Packaging250mg
  • Price$5670
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001416
  • Product descriptionA-484954 98.00%
  • Packaging10MG
  • Price$750.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001416
  • Product descriptionA-484954 98.00%
  • Packaging100MG
  • Price$1544.55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5618
  • Product descriptionA484954
  • Packaging5mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5618
  • Product descriptionA484954
  • Packaging10mg
  • Price$284
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5618
  • Product descriptionA484954
  • Packaging25mg
  • Price$614
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5618
  • Product descriptionA484954
  • Packaging50mg
  • Price$1087
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb572970
  • Product descriptionA-484954 >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb572970
  • Product descriptionA-484954 >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb572970
  • Product descriptionA-484954 >98%
  • Packaging1g
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17399
  • Product description7-Amino-1-cyclopropyl-3-ethyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide
  • Packaging25mg
  • Price$131.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28279
  • Product descriptionA-484954
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28279
  • Product descriptionA-484954
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28279
  • Product descriptionA-484954
  • Packaging10mg
  • Price$199
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28279
  • Product descriptionA-484954
  • Packaging25mg
  • Price$420
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0032949
  • Product descriptionA-484954 98.01%
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X5939 7-amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide 250mg $5670 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001416 A-484954 98.00% 10MG $750.75 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001416 A-484954 98.00% 100MG $1544.55 2021-12-16 Buy
ApexBio Technology B5618 A484954 5mg $158 2021-12-16 Buy
ApexBio Technology B5618 A484954 10mg $284 2021-12-16 Buy
ApexBio Technology B5618 A484954 25mg $614 2021-12-16 Buy
ApexBio Technology B5618 A484954 50mg $1087 2021-12-16 Buy
Biorbyt Ltd orb572970 A-484954 >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb572970 A-484954 >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb572970 A-484954 >98% 1g $2691.1 2021-12-16 Buy
Biosynth Carbosynth FA17399 7-Amino-1-cyclopropyl-3-ethyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide 25mg $131.5 2021-12-16 Buy
Cayman Chemical 28279 A-484954 1mg $32 2024-03-01 Buy
Cayman Chemical 28279 A-484954 5mg $116 2024-03-01 Buy
Cayman Chemical 28279 A-484954 10mg $199 2024-03-01 Buy
Cayman Chemical 28279 A-484954 25mg $420 2024-03-01 Buy
ChemScene CS-0032949 A-484954 98.01% 5mg $100 2021-12-16 Buy
Next Last

Properties

Boiling point :522.9±60.0 °C(Predicted)
Density :1.522±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :DMSO: soluble3mg/mL, clear (warmed)
pka :14.26±0.20(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

A-484954 is an ATP-competitive inhibitor of eukaryotic elongation factor-2 kinase (eEF-2K; IC50 = 420 nM). It reduces eEF-2K autophosphorylation in PC3, HeLa, H460, H1299, and MDA-MB-231 cancer cells when used at a concentration of 75 μM.

Suppliers and manufacturers

career henan chemical co
7-AMino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyriMidine-6-carboxaMide
$1.00 /1KG
7-AMino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyriMidine-6-carboxaMide CAS:142557-61-7
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
HANGZHOU CLAP TECHNOLOGY CO.,LTD
InvivoChem
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific J & K SCIENTIFIC LTD. Chembest Research Laboratories Limited Chemsky (shanghai) International Co.,Ltd Shanghai SynFarm Pharmaceutical Technology Co., Ltd.