2,3-Dihydro-2-(5-methyl-2-thienyl)-3-phenyl-4(1H)-quinazolinone
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- $32 - $731
- Product name: 2,3-Dihydro-2-(5-methyl-2-thienyl)-3-phenyl-4(1H)-quinazolinone
- CAS: 1429192-00-6
- MF: C19H16N2OS
- MW: 320.41
- EINECS:
- MDL Number:MFCD28124399
- Synonyms:2,3-Dihydro-2-(5-methyl-2-thienyl)-3-phenyl-4(1H)-quinazolinone;Retro-2;Retro-2 cycl;RN 1-001;4(1H)-Quinazolinone, 2,3-dihydro-2-(5-methyl-2-thienyl)-3-phenyl-;2-(5-methylthiophen-2-yl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one;Retro-2 >=98% (HPLC);2,3-Dihydro-2-(5-methyl-2-thienyl)-3-phenyl-4(1H)-quinazolin
15 prices
Selected condition：
Brand
- AK Scientific
- Apolloscientific
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product numberSYN5223
- Product descriptionRetro-2
- Packaging100mg
- Price$731
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0083
- Product descriptionRETRO-2 98%
- Packaging1mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0083
- Product descriptionRETRO-2 98%
- Packaging5mg
- Price$109
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0083
- Product descriptionRETRO-2 98%
- Packaging10mg
- Price$153
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21946
- Product descriptionRetro-2 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21946
- Product descriptionRetro-2 ≥98%
- Packaging5mg
- Price$100
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21946
- Product descriptionRetro-2 ≥98%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21946
- Product descriptionRetro-2 ≥98%
- Packaging25mg
- Price$420
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0064117
- Product descriptionRetro-2cycl 98.11%
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0064117
- Product descriptionRetro-2cycl 98.11%
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0064117
- Product descriptionRetro-2cycl 98.11%
- Packaging50mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0064117
- Product descriptionRetro-2cycl 98.11%
- Packaging100mg
- Price$520
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1085
- Product descriptionRetro-2 ≥98% (HPLC)
- Packaging5mg
- Price$118
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1085
- Product descriptionRetro-2 ≥98% (HPLC)
- Packaging25mg
- Price$498
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberR279010
- Product descriptionRetro-2
- Packaging10mg
- Price$220
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5223 | Retro-2 | 100mg | $731 | 2021-12-16 | Buy |
| Apolloscientific | BISN0083 | RETRO-2 98% | 1mg | $80 | 2021-12-16 | Buy |
| Apolloscientific | BISN0083 | RETRO-2 98% | 5mg | $109 | 2021-12-16 | Buy |
| Apolloscientific | BISN0083 | RETRO-2 98% | 10mg | $153 | 2021-12-16 | Buy |
| Cayman Chemical | 21946 | Retro-2 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21946 | Retro-2 ≥98% | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 21946 | Retro-2 ≥98% | 10mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 21946 | Retro-2 ≥98% | 25mg | $420 | 2024-03-01 | Buy |
| ChemScene | CS-0064117 | Retro-2cycl 98.11% | 5mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-0064117 | Retro-2cycl 98.11% | 10mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-0064117 | Retro-2cycl 98.11% | 50mg | $290 | 2021-12-16 | Buy |
| ChemScene | CS-0064117 | Retro-2cycl 98.11% | 100mg | $520 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML1085 | Retro-2 ≥98% (HPLC) | 5mg | $118 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1085 | Retro-2 ≥98% (HPLC) | 25mg | $498 | 2024-03-01 | Buy |
| TRC | R279010 | Retro-2 | 10mg | $220 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
form :powder
color :white to beige
solubility :DMSO: soluble10mg/mL, clear (warmed)
form :powder
color :white to beige
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Retro-2 is a selective inhibitor of retrograde protein trafficking mediated by syntaxin-5 at the interface between the endosome and trans-Golgi network, with no discernable effects on other intracellular trafficking pathways. Retro-2 inhibits ebolavirus infection with an EC50 value of 12.2 μM and reduces ricin-induced toxicity by 2.7-fold when used at a concentration of 20 μM in HeLa cells. Retro-2 also blocks JC polyomavirus, BK polyomavirus, and SV40 infectivity in Vero green monkey kidney epithelial cells in vitro (EC50s = 28.4, 61.2, and 58.6 μM, respectively). In mouse models, Retro-2 improves survival and reduces symptoms following infection with Shiga toxin-producing E. coli when administered at a dose of 100 mg/kg and protects against ricin challenge when administered prophylactically at a dose of 2 mg/kg.Suppliers and manufacturers
TargetMol Chemicals Inc.
Career Henan Chemica Co
Amadis Chemical Company Limited
Adamas Reagent, Ltd.
Sigma-Aldrich
Shanghaizehan biopharma technology co., Ltd.
Pharmacodia (Beijing) Co.,Ltd
Shanghai EFE Biological Technology Co., Ltd.
Tianjin Kailiqi Biotechnology Co., Ltd.
Beijing Solarbio Science & Tecnology Co., Ltd.