Abacavir Related CoMpound D
- $130 - $1360
- Product name: Abacavir Related CoMpound D
- CAS: 1443421-69-9
- MF: C18H21ClN10O
- MW: 428.88
- EINECS:
- MDL Number:MFCD28137825
- Synonyms:Abacavir Related CoMpound D;N6-Cyclopropyl-9-{(1R,4S)-4-[(2,5-diamino-6-chloropyrimidin-4-yloxy)methyl]cyclopent-2-enyl}-9H-purine-2,6-diamine;Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine;Abacavir EP Impurity B;O-Pyrimidine Derivative Abacavir (USP);6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(2,5-diamino-6-chloropyrimidin-4-yl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine;9H-Purine-2,6-diamine, N6-cyclopropyl-9-[(1R,4S)-4-[[(2,5-diamino-6-chloro-4-pyrimidinyl)oxy]methyl]-2-cyclopenten-1-yl]-;Abacavir Impurity D
4 prices
Selected condition:
Brand
- American Custom Chemicals Corporation
- Sigma-Aldrich
- TRC
Package
- 2.5mg
- 5MG
- 20mg
- 25mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0027217
- Product descriptionABACAVIR O-PYRIMIDINE IMPURITY 95.00%
- Packaging5MG
- Price$504.96
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number1000437
- Product descriptionAbacavir Related Compound D
- Packaging20mg
- Price$1360
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberA105035
- Product descriptionAbacavir5’-4-Chloro-6-methylpyrimidine-2,5-diamine
- Packaging25mg
- Price$1050
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberA105035
- Product descriptionAbacavir5’-4-Chloro-6-methylpyrimidine-2,5-diamine
- Packaging2.5mg
- Price$130
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0027217 | ABACAVIR O-PYRIMIDINE IMPURITY 95.00% | 5MG | $504.96 | 2021-12-16 | Buy |
Sigma-Aldrich | 1000437 | Abacavir Related Compound D | 20mg | $1360 | 2024-03-01 | Buy |
TRC | A105035 | Abacavir5’-4-Chloro-6-methylpyrimidine-2,5-diamine | 25mg | $1050 | 2021-12-16 | Buy |
TRC | A105035 | Abacavir5’-4-Chloro-6-methylpyrimidine-2,5-diamine | 2.5mg | $130 | 2021-12-16 | Buy |
Properties
Boiling point :830.1±75.0 °C(Predicted)
Density :1.90±0.1 g/cm3(Predicted)
pka :4.86±0.10(Predicted)
Density :1.90±0.1 g/cm3(Predicted)
pka :4.86±0.10(Predicted)
Safety Information
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Description
Abacavir 5’-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.More related product prices
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