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ChemicalBook >> CAS DataBase List >> 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid

14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid

14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid price.
  • $49 - $770
  • Product name: 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
  • CAS: 149402-51-7
  • MF: C39H48N4O4
  • MW: 636.82
  • EINECS:
  • MDL Number:MFCD11040935
  • Synonyms:Photochlor (HPPH);3-Phorbinepropanoic acid, 14-ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18 -tetramethyl-20-oxo-, (3S,4S)-;Sulcardine;14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid;2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a;(3S,4S)-14-Ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid;3-Devinyl-3-(1'-hexyloxy)ethylpyropheophorbide A;Photochlor (HTTP)
8 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number0412CB
  • Product description2-(1-Hexyloxyethyl)-2-devinylpyropheophorbide-a
  • Packaging1mg
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20611
  • Product descriptionHPPH ≥98% (mixture of epimers)
  • Packaging1mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20611
  • Product descriptionHPPH ≥98% (mixture of epimers)
  • Packaging5mg
  • Price$190
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20611
  • Product descriptionHPPH ≥98% (mixture of epimers)
  • Packaging10mg
  • Price$356
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20611
  • Product descriptionHPPH ≥98% (mixture of epimers)
  • Packaging25mg
  • Price$770
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberP365010
  • Product descriptionPhotochlor
  • Packaging5mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP365010
  • Product descriptionPhotochlor
  • Packaging25mg
  • Price$685
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number462546
  • Product descriptionPhotochlor
  • Packaging1mg
  • Price$305
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0412CB 2-(1-Hexyloxyethyl)-2-devinylpyropheophorbide-a 1mg $152 2021-12-16 Buy
Cayman Chemical 20611 HPPH ≥98% (mixture of epimers) 1mg $49 2024-03-01 Buy
Cayman Chemical 20611 HPPH ≥98% (mixture of epimers) 5mg $190 2024-03-01 Buy
Cayman Chemical 20611 HPPH ≥98% (mixture of epimers) 10mg $356 2024-03-01 Buy
Cayman Chemical 20611 HPPH ≥98% (mixture of epimers) 25mg $770 2024-03-01 Buy
TRC P365010 Photochlor 5mg $175 2021-12-16 Buy
TRC P365010 Photochlor 25mg $685 2021-12-16 Buy
Usbiological 462546 Photochlor 1mg $305 2021-12-16 Buy

Properties

Boiling point :992.5±65.0 °C(Predicted)
Density :1.184
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO:3.0(Max Conc. mg/mL);4.7(Max Conc. mM)
form :A crystalline solid
color :Light brown to black

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P341 IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

HPPH is a chlorin that acts as a photosensitizer in photodynamic therapy (PDT) when stimulated with light at 655 nm. When administered systemically, HPPH accumulates in tumor cells and, when stimulated with light in the presence of oxygen, reactive oxygen species (ROS) are generated, leading to necrosis within the tumor. HPPH, at a dose of 0.5 mg/kg, increases survival in a nude rat model of glioma. It works synergistically with gemcitabine in several pancreatic cancer cell lines to induce cell death.

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