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ChemicalBook >> CAS DataBase List >> (±)14(15)-EET-SI

(±)14(15)-EET-SI

(±)14(15)-EET-SI price.
  • $81 - $496.39
  • Product name: (±)14(15)-EET-SI
  • CAS: 218461-97-3
  • MF: C21H35NO4S
  • MW: 397.57
  • EINECS:
  • MDL Number:MFCD12912332
  • Synonyms:(±)14(15)-EET-SI;5,8,11-Tridecatrienamide, N-(methylsulfonyl)-13-(3-pentyl-2-oxiranyl)-, (5Z,8Z,11Z)-
4 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
Package
  • 25μg
  • 50μg
  • 100μg
  • 5MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000668
  • Product descriptionN-(METHYLSULFONYL)-13-(3-PENTYLOXIRANYL)-5Z,8Z,11Z-TRIDECATRIENAMIDE 95.00%
  • Packaging5MG
  • Price$496.39
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009286
  • Product description(±)14(15)-EET-SI ≥95%
  • Packaging25μg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009286
  • Product description(±)14(15)-EET-SI ≥95%
  • Packaging50μg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009286
  • Product description(±)14(15)-EET-SI ≥95%
  • Packaging100μg
  • Price$286
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation LIP0000668 N-(METHYLSULFONYL)-13-(3-PENTYLOXIRANYL)-5Z,8Z,11Z-TRIDECATRIENAMIDE 95.00% 5MG $496.39 2021-12-16 Buy
Cayman Chemical 10009286 (±)14(15)-EET-SI ≥95% 25μg $81 2024-03-01 Buy
Cayman Chemical 10009286 (±)14(15)-EET-SI ≥95% 50μg $152 2024-03-01 Buy
Cayman Chemical 10009286 (±)14(15)-EET-SI ≥95% 100μg $286 2024-03-01 Buy

Properties

Density :1.060±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS (pH 7.2) (1:2): 0.3 mg/ml
pka :4.63±0.40(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes. The EETs are released in response to acetylcholine, bradykinin, arachidonic acid, or cyclic stretch.1 (±)14(15)-EET-SI is the methyl sulfonamide analog of 14(15)-EET. This substitution results in a metabolically more stable compound because it is not sensitive to β-oxidation or membrane esterification. (±)14(15)-EET-SI is equipotent to 14(15)-EET in vascular agonist activity as measured by relaxation of precontracted bovine coronary arteries.1 In addition, 14(15)-EET and the methyl sulfonamide analog both stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells.2