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ChemicalBook >> CAS DataBase List >> 1-amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile

1-amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile

1-amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile price.
  • $32 - $978
  • Product name: 1-amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
  • CAS: 150651-39-1
  • MF: C20H13N5
  • MW: 323.35
  • EINECS:
  • MDL Number:MFCD01572665
  • Synonyms:1-amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile;Pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile, 1-amino-3-(4-methylphenyl)-;iFSP1;SW620,Gpx4-knockout,FSP1,Ferroptosis,cancer,FSP1-knockout,iFSP1,iFSP-1,iFSP 1,cell,U-373,A549,RSL3,NCl-H1437,inhibit,Inhibitor
Price8 Properties Safety Information Description
8 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • Cayman Chemical
Package
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1916CD
  • Product description1-Amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
  • Packaging10mg
  • Price$164
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1007917
  • Product description1-Amino-3-p-tolyl-benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile 98%
  • Packaging100mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1007917
  • Product description1-Amino-3-p-tolyl-benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile 98%
  • Packaging250mg
  • Price$396
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1007917
  • Product description1-Amino-3-p-tolyl-benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile 98%
  • Packaging1g
  • Price$978
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29483
  • Product descriptioniFSP1
  • Packaging100mg
  • Price$486
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29483
  • Product descriptioniFSP1
  • Packaging50mg
  • Price$261
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29483
  • Product descriptioniFSP1
  • Packaging5mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29483
  • Product descriptioniFSP1
  • Packaging10mg
  • Price$61
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1916CD 1-Amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile 10mg $164 2021-12-16 Buy
Ambeed A1007917 1-Amino-3-p-tolyl-benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile 98% 100mg $260 2021-12-16 Buy
Ambeed A1007917 1-Amino-3-p-tolyl-benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile 98% 250mg $396 2021-12-16 Buy
Ambeed A1007917 1-Amino-3-p-tolyl-benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile 98% 1g $978 2021-12-16 Buy
Cayman Chemical 29483 iFSP1 100mg $486 2024-03-01 Buy
Cayman Chemical 29483 iFSP1 50mg $261 2024-03-01 Buy
Cayman Chemical 29483 iFSP1 5mg $32 2024-03-01 Buy
Cayman Chemical 29483 iFSP1 10mg $61 2024-03-01 Buy

Properties

Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:30.0(Max Conc. mg/mL);92.78(Max Conc. mM)
form :A crystalline solid
pka :2.90±0.50(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

ChEBI: IFSP1 is a member of the class of pyridobenzimidazoles that is pyrido[1,2-a]benzimidazole substituted by amino, cyano, 4-methylphenyl, and cyano groups at positions 1, 2, 3 and 4, respectively. It is a potent inhibitor of ferroptosis suppressor protein 1 (FSP1) with EC50 of 103 nM. It induces ferroptosis in GPX4 knockout cells that overexpress FSP1. It has a role as a ferroptosis inducer, an antineoplastic agent and a ferroptosis suppressor protein 1 inhibitor. It is a member of toluenes, a nitrile, a primary amino compound, an aromatic amine and a pyridobenzimidazole.

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