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ChemicalBook >> CAS DataBase List >> 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone  hydrate,  NSC  656158 price.
  • $160 - $1302.49
  • Product name: 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158
  • CAS: 154554-41-3
  • MF: C16H10FNO3
  • MW: 283.25
  • EINECS:
  • MDL Number:MFCD11114577
  • Synonyms:2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158;CHM-1 hydrate;6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one;CHM 1;2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate;NSC 656158;6-(2-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one;1,3-Dioxolo[4,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)-
6 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • TRC
  • Usbiological
Package
  • 5MG
  • 10mg
  • 25MG
  • 50mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001053
  • Product descriptionCHM-1 HYDRATE 95.00%
  • Packaging5MG
  • Price$770.56
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001053
  • Product descriptionCHM-1 HYDRATE 95.00%
  • Packaging25MG
  • Price$1302.49
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4450
  • Product descriptionCHM1
  • Packaging10mg
  • Price$259
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4450
  • Product descriptionCHM1
  • Packaging50mg
  • Price$1095
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC381168
  • Product descriptionCHM-1
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number254966
  • Product descriptionCHM 1
  • Packaging10mg
  • Price$423
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation INB0001053 CHM-1 HYDRATE 95.00% 5MG $770.56 2021-12-16 Buy
American Custom Chemicals Corporation INB0001053 CHM-1 HYDRATE 95.00% 25MG $1302.49 2021-12-16 Buy
ApexBio Technology A4450 CHM1 10mg $259 2021-12-16 Buy
ApexBio Technology A4450 CHM1 50mg $1095 2021-12-16 Buy
TRC C381168 CHM-1 5mg $160 2021-12-16 Buy
Usbiological 254966 CHM 1 10mg $423 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
form :solid
color :Off-white to light yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

CHM-1 is a potent, selective antitumor agent in human hepatocellular carcinoma in vitro. CHM-1 induces apoptosis, and it binds tubulin and inhibits tubulin polymerization in vitro. Noted to cause cell cycle arrest at G2/M phase by activation of Cdc kinase activity. Also, CHM-1 exhibits vascular targeting activity through upregulation of p53 and induction of death receptor (DR5)-mediated apoptosis in HUVEC cells. Furthermore reported to induce translocation of apoptosis inducing factor (AIF) from the mitochondria to nucleus.