(3S,5R,8R,9S,10S,13R,14S,17R)-17-(3-furyl)-10,13-dimethyl-2,3,4,5,6,7, 8,9,11,12,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,14,17-triol
![(3S,5R,8R,9S,10S,13R,14S,17R)-17-(3-furyl)-10,13-dimethyl-2,3,4,5,6,7, 8,9,11,12,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,14,17-triol price.](/CAS/20150408/GIF/156722-18-8.gif)
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- $32 - $2839
- Product name: (3S,5R,8R,9S,10S,13R,14S,17R)-17-(3-furyl)-10,13-dimethyl-2,3,4,5,6,7, 8,9,11,12,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,14,17-triol
- CAS: 156722-18-8
- MF: C23H34O4
- MW: 374.51
- EINECS:
- MDL Number:MFCD00927279
- Synonyms:(3S,5R,8R,9S,10S,13R,14S,17R)-17-(3-furyl)-10,13-dimethyl-2,3,4,5,6,7, 8,9,11,12,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,14,17-triol;Rostafuroxin;PST2238;(3β,5β,14β)-21,23-Epoxy-24-Norchola-20,22-diene-3,14,17-triol;Rostafuroxin (PST-2238);(3beta,5beta,14beta)-21,23-Epoxy-24-norchola-20,22-diene-3,14,17-triol;Rostafuroxin PST2284;(3beta,5beta,14beta)-21,23-Epoxy-24-norchola-20,22-diene-3,14,17-triol Rostafuroxin (PST 2238)
27 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 25mg
- 10
- 50mg
- 50
- 1mg
- 10mM(in 1mL DMSO)
- 100mg
- 250mg
- 1000mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5227
- Product descriptionRostafuroxin
- Packaging10mg
- Price$155
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5894
- Product descriptionRostafuroxin(PST2238)
- Packaging10mM(in 1mL DMSO)
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5894
- Product descriptionRostafuroxin(PST2238)
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5894
- Product descriptionRostafuroxin(PST2238)
- Packaging50mg
- Price$585
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181312
- Product descriptionRostafuroxin >98%
- Packaging1000mg
- Price$2839
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181312
- Product descriptionRostafuroxin >98%
- Packaging250mg
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181312
- Product descriptionRostafuroxin >98%
- Packaging100mg
- Price$838.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21282
- Product descriptionRostafuroxin ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21282
- Product descriptionRostafuroxin ≥98%
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21282
- Product descriptionRostafuroxin ≥98%
- Packaging10mg
- Price$169
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21282
- Product descriptionRostafuroxin ≥98%
- Packaging25mg
- Price$381
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM196393
- Product descriptionPST2238(Rostafuroxin) 98%
- Packaging50mg
- Price$383
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3295
- Product descriptionRostafuroxin 98.07%
- Packaging5mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3295
- Product descriptionRostafuroxin 98.07%
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3295
- Product descriptionRostafuroxin 98.07%
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3295
- Product descriptionRostafuroxin 98.07%
- Packaging100mg
- Price$750
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5227 | Rostafuroxin | 10mg | $155 | 2021-12-16 | Buy |
| ApexBio Technology | B5894 | Rostafuroxin(PST2238) | 10mM(in 1mL DMSO) | $80 | 2021-12-16 | Buy |
| ApexBio Technology | B5894 | Rostafuroxin(PST2238) | 10mg | $135 | 2021-12-16 | Buy |
| ApexBio Technology | B5894 | Rostafuroxin(PST2238) | 50mg | $585 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181312 | Rostafuroxin >98% | 1000mg | $2839 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181312 | Rostafuroxin >98% | 250mg | $1504.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181312 | Rostafuroxin >98% | 100mg | $838.1 | 2021-12-16 | Buy |
| Cayman Chemical | 21282 | Rostafuroxin ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21282 | Rostafuroxin ≥98% | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 21282 | Rostafuroxin ≥98% | 10mg | $169 | 2024-03-01 | Buy |
| Cayman Chemical | 21282 | Rostafuroxin ≥98% | 25mg | $381 | 2024-03-01 | Buy |
| Chemenu | CM196393 | PST2238(Rostafuroxin) 98% | 50mg | $383 | 2021-12-16 | Buy |
| ChemScene | CS-3295 | Rostafuroxin 98.07% | 5mg | $75 | 2021-12-16 | Buy |
| ChemScene | CS-3295 | Rostafuroxin 98.07% | 10mg | $135 | 2021-12-16 | Buy |
| ChemScene | CS-3295 | Rostafuroxin 98.07% | 50mg | $450 | 2021-12-16 | Buy |
| ChemScene | CS-3295 | Rostafuroxin 98.07% | 100mg | $750 | 2021-12-16 | Buy |
Properties
Boiling point :451.3±45.0 °C(Predicted)
Density :1.226±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥12.05 mg/mL in DMSO
form :solid
pka :14.02±0.70(Predicted)
color :White to off-white
Density :1.226±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥12.05 mg/mL in DMSO
form :solid
pka :14.02±0.70(Predicted)
color :White to off-white
Safety Information
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Description
Rostafuroxin potently inhibits binding of endogenous ouabain to the Na+/K+ ATPase (IC50 = 1.7 μM) through the Src-epidermal growth factor receptor (EGFR)-dependent signaling pathway. This blocks the ouabain-dependent increase in Na+/K+ ATPase activity. In cultured renal cells where the Na+/K+ ATPase is upregulated or has increased activity, rostafuroxin normalizes mRNA levels and Na+/K+ ATPase activity. At very low doses (1 and 10 μg/kg for 5-6 weeks) in Milan-hypertensive rats, it decreased the development of hypertension. In a Phase II clinical study, rostafuroxin did not reduce blood pressure in human patients at doses of 0.05-5.0 mg/d.Suppliers and manufacturers
BOC Sciences
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Baoji Guokang Bio-Technology Co., Ltd.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
LEAP CHEM CO., LTD.
Hangzhou MolCore BioPharmatech Co.,Ltd.
ShenZhen Trendseen Biological Technology Co.,Ltd.
GIHI CHEMICALS CO.,LIMITED
