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ChemicalBook >> CAS DataBase List >> 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole

5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole

5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole price.
  • $27 - $3000
  • Product name: 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole
  • CAS: 1570496-34-2
  • MF: C25H25F3N6O4S
  • MW: 562.56
  • EINECS:
  • MDL Number:MFCD30489429
  • Synonyms:5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole;4-(Methylsulfonyl)-1-[3-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-1,2,4-triazol-1-yl]methyl]phenyl]piperidine (IACS-010759);5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-ox;Piperidine, 4-(methylsulfonyl)-1-[3-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-1,2,4-triazol-1-yl]methyl]phenyl]-;5-[5-Methyl-1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole;IACS-010759; IACS 010759; IACS010759; IACS-10759; IACS 10759; IACS10759;CPD1805;CS-2899
Price13 Properties Safety Information Description
13 prices
Selected condition：
Brand
  • AK Scientific
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product number6948EA
  • Product description5-[5-Methyl-1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole
  • Packaging50mg
  • Price$927
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2909
  • Product descriptionIACS-010759-IACS-10759 99%
  • Packaging5mg
  • Price$104.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM165719
  • Product descriptionIACS 010759
  • Packaging50mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25867
  • Product descriptionIACS-010759
  • Packaging1mg
  • Price$27
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25867
  • Product descriptionIACS-010759
  • Packaging5mg
  • Price$88
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25867
  • Product descriptionIACS-010759
  • Packaging10mg
  • Price$149
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25867
  • Product descriptionIACS-010759
  • Packaging25mg
  • Price$236
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM328316
  • Product description5-[5-Methyl-1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole 95%+
  • Packaging10mg
  • Price$217
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM328316
  • Product description5-[5-Methyl-1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole 95%+
  • Packaging50mg
  • Price$643
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM328316
  • Product description5-[5-Methyl-1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole 95%+
  • Packaging100mg
  • Price$939
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC11262
  • Product descriptionIACS-010759 >98%
  • Packaging100mg
  • Price$850
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC11262
  • Product descriptionIACS-010759 >98%
  • Packaging1g
  • Price$3000
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberM329473
  • Product description4-(Methylsulfonyl)-1-[3-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-1,2,4-triazol-1-yl]methyl]phenyl]piperidine(IACS-010759)
  • Packaging25mg
  • Price$1175
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6948EA 5-[5-Methyl-1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole 50mg $927 2021-12-16 Buy
Axon Medchem Axon2909 IACS-010759-IACS-10759 99% 5mg $104.5 2021-12-16 Buy
Biosynth Carbosynth FM165719 IACS 010759 50mg $650 2021-12-16 Buy
Cayman Chemical 25867 IACS-010759 1mg $27 2024-03-01 Buy
Cayman Chemical 25867 IACS-010759 5mg $88 2024-03-01 Buy
Cayman Chemical 25867 IACS-010759 10mg $149 2024-03-01 Buy
Cayman Chemical 25867 IACS-010759 25mg $236 2024-03-01 Buy
Chemenu CM328316 5-[5-Methyl-1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole 95%+ 10mg $217 2021-12-16 Buy
Chemenu CM328316 5-[5-Methyl-1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole 95%+ 50mg $643 2021-12-16 Buy
Chemenu CM328316 5-[5-Methyl-1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole 95%+ 100mg $939 2021-12-16 Buy
DC Chemicals DC11262 IACS-010759 >98% 100mg $850 2021-12-16 Buy
DC Chemicals DC11262 IACS-010759 >98% 1g $3000 2021-12-16 Buy
TRC M329473 4-(Methylsulfonyl)-1-[3-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-1,2,4-triazol-1-yl]methyl]phenyl]piperidine(IACS-010759) 25mg $1175 2021-12-16 Buy

Properties

Boiling point :768.0±70.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:24.23(Max Conc. mg/mL);43.07(Max Conc. mM)
DMF:0.1(Max Conc. mg/mL);0.18(Max Conc. mM) form :A crystalline solid
pka :3.24±0.40(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

4-(Methylsulfonyl)-1-[3-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-1,2,4-triazol-1-yl]methyl]phenyl]piperidine is a drug candidate that acts as a modulator of HIF activity for treatment of cancer and other hypoxia-mediated diseases.

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