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ChemicalBook >> CAS DataBase List >> 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate

4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate

4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate price.
  • $81 - $1620
  • Product name: 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
  • CAS: 1577222-14-0
  • MF: C11H13NO6
  • MW: 255.22
  • EINECS:-0
  • MDL Number:MFCD28502263
  • Synonyms:(2E)-2-Butenedioic acid 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester;2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate;4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate;ALKS-8700;diroximel fumarate;DiroximelFumarete,ALKS-8700,4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate;2-Butenedioic acid (2E)-, 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester;5-dioxopyrrolidin-1-yl)ethyl methyl fumarate
Price8 Properties Safety Information Description
8 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • DC Chemicals
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number6016DW
  • Product descriptionDiroximelfumarate
  • Packaging50mg
  • Price$714
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29111
  • Product descriptionDiroximel Fumarate
  • Packaging5mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29111
  • Product descriptionDiroximel Fumarate
  • Packaging10mg
  • Price$143
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29111
  • Product descriptionDiroximel Fumarate
  • Packaging25mg
  • Price$336
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29111
  • Product descriptionDiroximel Fumarate
  • Packaging50mg
  • Price$553
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10582
  • Product descriptionDiroximelFumarete(ALKS-8700) >98%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10582
  • Product descriptionDiroximelFumarete(ALKS-8700) >98%
  • Packaging250mg
  • Price$810
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10582
  • Product descriptionDiroximelFumarete(ALKS-8700) >98%
  • Packaging1g
  • Price$1620
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6016DW Diroximelfumarate 50mg $714 2021-12-16 Buy
Cayman Chemical 29111 Diroximel Fumarate 5mg $81 2024-03-01 Buy
Cayman Chemical 29111 Diroximel Fumarate 10mg $143 2024-03-01 Buy
Cayman Chemical 29111 Diroximel Fumarate 25mg $336 2024-03-01 Buy
Cayman Chemical 29111 Diroximel Fumarate 50mg $553 2024-03-01 Buy
DC Chemicals DC10582 DiroximelFumarete(ALKS-8700) >98% 100mg $450 2021-12-16 Buy
DC Chemicals DC10582 DiroximelFumarete(ALKS-8700) >98% 250mg $810 2021-12-16 Buy
DC Chemicals DC10582 DiroximelFumarete(ALKS-8700) >98% 1g $1620 2021-12-16 Buy

Properties

Melting point :96 - 99°C
Boiling point :441.0±25.0 °C(Predicted)
Density :1.319±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :-1.60±0.20(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Diroximel fumarate is a prodrug form of monomethyl fumarate . It undergoes esterase cleavage in the gut to release monomethyl fumarate. Formulations containing diroximel fumarate have been used in the treatment of relapsing-remitting multiple sclerosis.

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Suppliers and manufacturers

Career Henan Chemica Co
4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
$1.00 /1KG
4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate CAS:1577222-14-0
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