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ChemicalBook >> CAS DataBase List >> 5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE

5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE

$44 - $5383
Product name: 5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE
CAS: 163769-88-8
MF: C22H21N3O2
MW: 359.42
EINECS:
MDL Number:MFCD00354370
Synonyms:Benz[7,8]indolizino[2,3-b]quinoxaline,5,6-dihydro-2,3-dimethoxy-6,6-dimethyl-;5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE;YM 90709;2,3-Dimethoxy-6,6-dimethyl-5,6-dihydrobenzo[7,8]indolizino[2,3-b]quinoxaline;YM 90709;YM90709;YM-90709;YM-90709,GM-CSF,inhibit,Inhibitor,Interleukin Related,IL-5,eosinophils,IL-5R,JAK2

Price29 Properties Safety Information Description

29 prices

Selected condition：

Brand

aablocks
AK Scientific
Ambeed
Arctom
Cayman Chemical
ChemScene
Crysdot
CSNpharm
DC Chemicals
Tocris
TRC

Package

10
1mg
5mg
10mg
25mg
50mg
100mg
1g

Manufactureraablocks
Product numberAA001UB5
Product descriptionBenz[7,8]indolizino[2,3-b]quinoxaline,5,6-dihydro-2,3-dimethoxy-6,6-dimethyl- 99%
Packaging5mg
Price$144
Updated2021-12-16
Buy

Manufactureraablocks
Product numberAA001UB5
Product descriptionBenz[7,8]indolizino[2,3-b]quinoxaline,5,6-dihydro-2,3-dimethoxy-6,6-dimethyl- 99%
Packaging10mg
Price$219
Updated2021-12-16
Buy

Manufactureraablocks
Product numberAA001UB5
Product descriptionBenz[7,8]indolizino[2,3-b]quinoxaline,5,6-dihydro-2,3-dimethoxy-6,6-dimethyl- 99%
Packaging25mg
Price$369
Updated2021-12-16
Buy

Manufactureraablocks
Product numberAA001UB5
Product descriptionBenz[7,8]indolizino[2,3-b]quinoxaline,5,6-dihydro-2,3-dimethoxy-6,6-dimethyl- 99%
Packaging50mg
Price$635
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number4791CE
Product description16,17-Dimethoxy-21,21-dimethyl-1,3,10-triazapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-2,4,6,8,10,12,14,16,18-nonaene
Packaging5mg
Price$97
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number4791CE
Product description16,17-Dimethoxy-21,21-dimethyl-1,3,10-triazapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-2,4,6,8,10,12,14,16,18-nonaene
Packaging10mg
Price$109
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number4791CE
Product description16,17-Dimethoxy-21,21-dimethyl-1,3,10-triazapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-2,4,6,8,10,12,14,16,18-nonaene
Packaging50mg
Price$154
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA265624
Product descriptionYM-90709 98+%
Packaging1mg
Price$44
Updated2021-12-16
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ManufacturerAmbeed
Product numberA265624
Product descriptionYM-90709 98+%
Packaging5mg
Price$155
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA265624
Product descriptionYM-90709 98+%
Packaging10mg
Price$263
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA265624
Product descriptionYM-90709 98+%
Packaging25mg
Price$447
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA265624
Product descriptionYM-90709 98+%
Packaging1g
Price$5383
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS500451
Product descriptionYM-90709 ≥98%
Packaging1mg
Price$44
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number23448
Product descriptionYM-90709 ≥98%
Packaging5mg
Price$93
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number23448
Product descriptionYM-90709 ≥98%
Packaging10mg
Price$166
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number23448
Product descriptionYM-90709 ≥98%
Packaging25mg
Price$365
Updated2024-03-01
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA001UB5	Benz[7,8]indolizino[2,3-b]quinoxaline,5,6-dihydro-2,3-dimethoxy-6,6-dimethyl- 99%	5mg	$144	2021-12-16	Buy
aablocks	AA001UB5	Benz[7,8]indolizino[2,3-b]quinoxaline,5,6-dihydro-2,3-dimethoxy-6,6-dimethyl- 99%	10mg	$219	2021-12-16	Buy
aablocks	AA001UB5	Benz[7,8]indolizino[2,3-b]quinoxaline,5,6-dihydro-2,3-dimethoxy-6,6-dimethyl- 99%	25mg	$369	2021-12-16	Buy
aablocks	AA001UB5	Benz[7,8]indolizino[2,3-b]quinoxaline,5,6-dihydro-2,3-dimethoxy-6,6-dimethyl- 99%	50mg	$635	2021-12-16	Buy
AK Scientific	4791CE	16,17-Dimethoxy-21,21-dimethyl-1,3,10-triazapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-2,4,6,8,10,12,14,16,18-nonaene	5mg	$97	2021-12-16	Buy
AK Scientific	4791CE	16,17-Dimethoxy-21,21-dimethyl-1,3,10-triazapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-2,4,6,8,10,12,14,16,18-nonaene	10mg	$109	2021-12-16	Buy
AK Scientific	4791CE	16,17-Dimethoxy-21,21-dimethyl-1,3,10-triazapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-2,4,6,8,10,12,14,16,18-nonaene	50mg	$154	2021-12-16	Buy
Ambeed	A265624	YM-90709 98+%	1mg	$44	2021-12-16	Buy
Ambeed	A265624	YM-90709 98+%	5mg	$155	2021-12-16	Buy
Ambeed	A265624	YM-90709 98+%	10mg	$263	2021-12-16	Buy
Ambeed	A265624	YM-90709 98+%	25mg	$447	2021-12-16	Buy
Ambeed	A265624	YM-90709 98+%	1g	$5383	2021-12-16	Buy
Arctom	AS500451	YM-90709 ≥98%	1mg	$44	2021-12-16	Buy
Cayman Chemical	23448	YM-90709 ≥98%	5mg	$93	2024-03-01	Buy
Cayman Chemical	23448	YM-90709 ≥98%	10mg	$166	2024-03-01	Buy
Cayman Chemical	23448	YM-90709 ≥98%	25mg	$365	2024-03-01	Buy

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Properties

Boiling point :579.6±50.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml
form :A crystalline solid
pka :2.74±0.40(Predicted)
color :Brown to orange

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501

Precautionary statements:

P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330	Rinse mouth.
P501	Dispose of contents/container to..…

Description

YM-90709 is a competitive antagonist of the interleukin-5 (IL-5) receptor that has IC₅₀ values of 1 and 0.57 μM for peripheral human eosinophils and eosinophilic HL-60 clone 15 cells, respectively, in a radioligand binding assay. It inhibits IL-5-induced eosinophil survival (IC₅₀ = 0.45 μM) and JAK2 phosphorylation in vitro. YM-90709 inhibits eosinophil and lymphocyte infiltration (ED₅₀s = 0.32 and 0.12 mg/kg, respectively) into the brochoalveolar lavage fluid (BALF) of rats and eosinophil infiltration (ED₅₀ = 0.05 mg/kg) into the BALF of mice in models of airway inflammation.

More related product prices

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Suppliers and manufacturers

career henan chemical co

$1.00 /1g
5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE CAS:163769-88-8

TargetMol Chemicals Inc.

$30.00 /1mg
YM-90709 CAS:163769-88-8

ATK CHEMICAL COMPANY LIMITED

Alchem Pharmtech,Inc.

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

HANGZHOU CLAP TECHNOLOGY CO.,LTD

InvivoChem

TargetMol Chemicals Inc.

ShenZhen Trendseen Biological Technology Co.,Ltd.

Aladdin Scientific

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5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers