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ChemicalBook >> CAS DataBase List >> NALPHA-METHYLHISTAMINE DIHYDROCHLORIDE

NALPHA-METHYLHISTAMINE DIHYDROCHLORIDE

NALPHA-METHYLHISTAMINE DIHYDROCHLORIDE price.
  • $131 - $2160
  • Product name: NALPHA-METHYLHISTAMINE DIHYDROCHLORIDE
  • CAS: 16503-22-3
  • MF: C6H11N3.2HCl
  • MW: 0
  • EINECS:
  • MDL Number:MFCD00134838
  • Synonyms:n-Methylhistamine dihydrochloride;NAMH dihydrochloride;[2-(1H-imidazol-4-yl)ethyl](methyl)amine dihydrochloride;Nα-Methylhistamine dihydrochloride;Nα-Methylhistamine;2-(1H-Imidazol-4-yl)-N-methylethanamine dihydrochloride;Nα Methylhistamine dihydrochloride,NαMethylhistamine dihydrochloride
Price11 Properties Safety Information Description
11 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 10
  • 50
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 2.5g
  • 5g
  • ManufacturerAK Scientific
  • Product number6570BB
  • Product descriptionNalpha-Methylhistaminedihydrochloride
  • Packaging100mg
  • Price$322
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6570BB
  • Product descriptionNalpha-Methylhistaminedihydrochloride
  • Packaging2.5g
  • Price$1502
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6570BB
  • Product descriptionNalpha-Methylhistaminedihydrochloride
  • Packaging5g
  • Price$2160
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0003720
  • Product descriptionN-ALPHA-METHYLHISTAMINE DIHYDROCHLORIDE 95.00%
  • Packaging100MG
  • Price$384.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6357
  • Product descriptionNα-Methylhistamine dihydrochloride
  • Packaging10mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6357
  • Product descriptionNα-Methylhistamine dihydrochloride
  • Packaging50mg
  • Price$959
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberH5914
  • Product descriptionNα-Methylhistamine dihydrochloride solid
  • Packaging10mg
  • Price$165
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberH5914
  • Product descriptionNα-Methylhistamine dihydrochloride solid
  • Packaging50mg
  • Price$632
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number0573
  • Product descriptionN-Methylhistaminedihydrochloride
  • Packaging10
  • Price$131
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number0573
  • Product descriptionN-Methylhistaminedihydrochloride
  • Packaging50
  • Price$495
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB496303
  • Product descriptionNα-Methylhistamine dihydrochloride
  • Packaging5mg
  • Price$225
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6570BB Nalpha-Methylhistaminedihydrochloride 100mg $322 2021-12-16 Buy
AK Scientific 6570BB Nalpha-Methylhistaminedihydrochloride 2.5g $1502 2021-12-16 Buy
AK Scientific 6570BB Nalpha-Methylhistaminedihydrochloride 5g $2160 2021-12-16 Buy
American Custom Chemicals Corporation INB0003720 N-ALPHA-METHYLHISTAMINE DIHYDROCHLORIDE 95.00% 100MG $384.3 2021-12-16 Buy
ApexBio Technology B6357 Nα-Methylhistamine dihydrochloride 10mg $228 2021-12-16 Buy
ApexBio Technology B6357 Nα-Methylhistamine dihydrochloride 50mg $959 2021-12-16 Buy
Sigma-Aldrich H5914 Nα-Methylhistamine dihydrochloride solid 10mg $165 2024-03-01 Buy
Sigma-Aldrich H5914 Nα-Methylhistamine dihydrochloride solid 50mg $632 2024-03-01 Buy
Tocris 0573 N-Methylhistaminedihydrochloride 10 $131 2021-12-16 Buy
Tocris 0573 N-Methylhistaminedihydrochloride 50 $495 2021-12-16 Buy
TRC B496303 Nα-Methylhistamine dihydrochloride 5mg $225 2021-12-16 Buy

Properties

Melting point :173-176°C
storage temp. :2-8°C
solubility :H2O: >20mg/mL
form :solid
color :white
Water Solubility :Soluble to 100 mM in water
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

Production of N-alpha-methyl-histamine, which is a histamine 3 receptor (H3R) agonist, is promoted in Helicobacter pylori infected human gastric mucosa. NAMH acts directly on H2Rs in animals to stimulate acid secretion and to be a H2R agonist. NAMH dose dependently stimulated cAMP productions in CHO-H2R cells. This production was inhibited by famotidine but not by thioperamide. Control CHO cells were unresponsive to either histamine or NAMH. In addition, the effect of NAMH, in terms of cAMP production in CHO-H2R cells, was more potent than that of histamine-that is, with a lower EC50 concentration and higher maximal cAMP production. Both NAMH and histamine, but not R-alpha-methyl-histamine, effectively inhibited [(3)H] tiotidine binding to CHO-H2R cells. These results confirm that NAMH, which is produced in the gastric mucosa by H pylori, is a potent H2R agonist as well as a H3R agonist.

Suppliers and manufacturers

TargetMol Chemicals Inc. Sigma-Aldrich Jiangsu aikang biomedical research and development co., LTD MedBioPharmaceutical Technology Inc Energy Chemical TargetMol Chemicals Inc. Shanghai Haohong Scientific Co., Ltd. ApexBio Technology