(5S,6R,15R)-5,6,15-TRIHYDROXY-7,9,13-TRANS-11-CIS-EICOSATETRAENOIC ACID
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- $201 - $1601
- Product name: (5S,6R,15R)-5,6,15-TRIHYDROXY-7,9,13-TRANS-11-CIS-EICOSATETRAENOIC ACID
- CAS: 171030-11-8
- MF: C20H32O5
- MW: 352.47
- EINECS:
- MDL Number:MFCD02259382
- Synonyms:LXA4-15-EPI;LIPOXIN A4, 15-EPI;5(S),6(R),15(R)-Lipoxin A4;15(R)-Lipoxin A4;15(R)-LXA4;(5S,6R,15R)-5,6,15-TRIHYDROXY-7,9,13-TRANS-11-CIS-EICOSATETRAENOIC ACID;ASPIRIN-TRIGGERED LXA4;Lipoxin A, 15-epi - CAS 171030-11-8 - Calbiochem
5 prices
Selected condition：
Brand
- Cayman Chemical
- Sigma-Aldrich
Package
- 25μg
- 50μg
- 100μg
- 250μg
- ManufacturerCayman Chemical
- Product number90415
- Product description15(R)-Lipoxin A4 ≥95%
- Packaging25μg
- Price$201
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number90415
- Product description15(R)-Lipoxin A4 ≥95%
- Packaging50μg
- Price$382
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number90415
- Product description15(R)-Lipoxin A4 ≥95%
- Packaging100μg
- Price$722
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number90415
- Product description15(R)-Lipoxin A4 ≥95%
- Packaging250μg
- Price$1601
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number437725
- Product descriptionLipoxin A₄, 15-epi - CAS 171030-11-8 - Calbiochem Lipoxin A?, 15-epi, CAS 171030-11-8, is an epimeric lipoxin A4 (Cat. No. 437720) analog that is more potent and metabolically stable than LXA4.
- Packaging25μg
- Price$462
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 90415 | 15(R)-Lipoxin A4 ≥95% | 25μg | $201 | 2024-03-01 | Buy |
| Cayman Chemical | 90415 | 15(R)-Lipoxin A4 ≥95% | 50μg | $382 | 2024-03-01 | Buy |
| Cayman Chemical | 90415 | 15(R)-Lipoxin A4 ≥95% | 100μg | $722 | 2024-03-01 | Buy |
| Cayman Chemical | 90415 | 15(R)-Lipoxin A4 ≥95% | 250μg | $1601 | 2024-03-01 | Buy |
| Sigma-Aldrich | 437725 | Lipoxin A₄, 15-epi - CAS 171030-11-8 - Calbiochem Lipoxin A?, 15-epi, CAS 171030-11-8, is an epimeric lipoxin A4 (Cat. No. 437720) analog that is more potent and metabolically stable than LXA4. | 25μg | $462 | 2024-03-01 | Buy |
Properties
Boiling point :589.4±50.0 °C(Predicted)
Density :1.096±0.06 g/cm3(Predicted)
storage temp. := -70C
solubility :DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
form :Liquid
pka :4.67±0.10(Predicted)
Density :1.096±0.06 g/cm3(Predicted)
storage temp. := -70C
solubility :DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
form :Liquid
pka :4.67±0.10(Predicted)
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 15(R)-Lipoxin A4 (15(R)-LXA4) is derived from the aspirin-triggered formation of 15(R)-HETE from arachidonic acid . 15(R)-LXA4 inhibits LTB4-induced chemotaxis, adherence, and transmigration of neutrophils with twice the potency of LXA4 demonstrating activity in the nM range. The anti-inflammatory effects of aspirin may be ascribed in part to the ability of 15(R)-LXA4 to regulate leukocyte function. 15(R)-LXA4 is reported to promote resolution of inflammation in LPS-treated stromal cells derived from intermediate-stage diseased supraspinatus tendons as evidenced by increased expression of the STAT-6 pathway target genes, ALOX15 and CD206.More related product prices
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