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ChemicalBook >> CAS DataBase List >> (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate

(R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate

(R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate price.
  • $32 - $7400
  • Product name: (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate
  • CAS: 179386-44-8
  • MF: C15H17N3O5
  • MW: 319.32
  • EINECS:604-604-1
  • MDL Number:MFCD09832637
  • Synonyms:(R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate;PNU 95666;Sumanirole maleate;U 95666E(Sumanirole maleate);U95666E;PNU 95666E;(5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate;(R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate
Price29 Properties Safety Information Description
29 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 5mg
  • 10mg
  • 10
  • 1mg
  • 50
  • 25mg
  • 50MG
  • 100mg
  • 250mg
  • 1G
  • ManufacturerAK Scientific
  • Product number2736AH
  • Product descriptionSumanirole maleate
  • Packaging10mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000868
  • Product description(R)-5-(METHYLAMINO)-5,6-DIHYDRO-1H-IMIDAZO[4,5,1-IJ]QUINOLIN-2(4H)-ONE MALEATE 95.00%
  • Packaging10MG
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000868
  • Product description(R)-5-(METHYLAMINO)-5,6-DIHYDRO-1H-IMIDAZO[4,5,1-IJ]QUINOLIN-2(4H)-ONE MALEATE 95.00%
  • Packaging50MG
  • Price$840
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000868
  • Product description(R)-5-(METHYLAMINO)-5,6-DIHYDRO-1H-IMIDAZO[4,5,1-IJ]QUINOLIN-2(4H)-ONE MALEATE 95.00%
  • Packaging1G
  • Price$7400
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS65180
  • Product descriptionSumanirole maleate
  • Packaging5mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS65180
  • Product descriptionSumanirole maleate
  • Packaging10mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS65180
  • Product descriptionSumanirole maleate
  • Packaging25mg
  • Price$272.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS65180
  • Product descriptionSumanirole maleate
  • Packaging50mg
  • Price$472.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11984
  • Product descriptionSumanirole (maleate) ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11984
  • Product descriptionSumanirole (maleate) ≥98%
  • Packaging5mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11984
  • Product descriptionSumanirole (maleate) ≥98%
  • Packaging10mg
  • Price$184
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0353
  • Product descriptionSumanirole maleate >98.0%
  • Packaging5mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0353
  • Product descriptionSumanirole maleate >98.0%
  • Packaging25mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0353
  • Product descriptionSumanirole maleate >98.0%
  • Packaging50mg
  • Price$530
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0353
  • Product descriptionSumanirole maleate >98.0%
  • Packaging100mg
  • Price$920
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002929
  • Product descriptionSumanirole maleate 98+%
  • Packaging5mg
  • Price$62
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2736AH Sumanirole maleate 10mg $232 2021-12-16 Buy
American Custom Chemicals Corporation INB0000868 (R)-5-(METHYLAMINO)-5,6-DIHYDRO-1H-IMIDAZO[4,5,1-IJ]QUINOLIN-2(4H)-ONE MALEATE 95.00% 10MG $520 2021-12-16 Buy
American Custom Chemicals Corporation INB0000868 (R)-5-(METHYLAMINO)-5,6-DIHYDRO-1H-IMIDAZO[4,5,1-IJ]QUINOLIN-2(4H)-ONE MALEATE 95.00% 50MG $840 2021-12-16 Buy
American Custom Chemicals Corporation INB0000868 (R)-5-(METHYLAMINO)-5,6-DIHYDRO-1H-IMIDAZO[4,5,1-IJ]QUINOLIN-2(4H)-ONE MALEATE 95.00% 1G $7400 2021-12-16 Buy
Biosynth Carbosynth FS65180 Sumanirole maleate 5mg $75 2021-12-16 Buy
Biosynth Carbosynth FS65180 Sumanirole maleate 10mg $135 2021-12-16 Buy
Biosynth Carbosynth FS65180 Sumanirole maleate 25mg $272.5 2021-12-16 Buy
Biosynth Carbosynth FS65180 Sumanirole maleate 50mg $472.5 2021-12-16 Buy
Cayman Chemical 11984 Sumanirole (maleate) ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 11984 Sumanirole (maleate) ≥98% 5mg $100 2024-03-01 Buy
Cayman Chemical 11984 Sumanirole (maleate) ≥98% 10mg $184 2024-03-01 Buy
ChemScene CS-0353 Sumanirole maleate >98.0% 5mg $75 2021-12-16 Buy
ChemScene CS-0353 Sumanirole maleate >98.0% 25mg $280 2021-12-16 Buy
ChemScene CS-0353 Sumanirole maleate >98.0% 50mg $530 2021-12-16 Buy
ChemScene CS-0353 Sumanirole maleate >98.0% 100mg $920 2021-12-16 Buy
Crysdot CD31002929 Sumanirole maleate 98+% 5mg $62 2021-12-16 Buy
Next Last

Properties

Melting point :200-208°C (dec.)
storage temp. :-20°C
solubility :H2O: soluble10mg/mL, clear
form :powder
color :white to beige
optical activity :[α]/D -22 to -32°, c = 1 in H2O

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Sumanirole is a high affinity D2 receptor agonist (EC50 values are between 17 and 75 nM in cell-based assays). Sumanirole displays >200-fold selectivity for the D2 receptor against other dopamine receptor subtypes (Ki values are 9.0, 1940, >2190 and >7140 for D2, D3, D4 and D1 receptors respectively). Sumanirole exhibits antiParkinsonian activity similar to Ropinirole (R641000).

Suppliers and manufacturers

CONIER CHEM AND PHARMA LIMITED
Career Henan Chemica Co
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
Amadis Chemical Company Limited Chembest Research Laboratories Limited Nanjing Chemlin Chemical Co., Ltd Shanghai Holy Biohemdeviser Co., Ltd NCE Biomedical Co.,Ltd. Shanghai T&W Pharmaceutical Co., Ltd.