Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> AMD 3465 (*Hexahydrobromide*)

AMD 3465 (*Hexahydrobromide*)

AMD 3465 (*Hexahydrobromide*) price.
  • $55 - $2245.7
  • Product name: AMD 3465 (*Hexahydrobromide*)
  • CAS: 185991-07-5
  • MF: C24H39BrN6
  • MW: 491.52
  • EINECS:
  • MDL Number:MFCD20926342
  • Synonyms:AMD 3465 (*Hexahydrobromide*);AMD 3465;AMD 3465 (hydrobroMide);1-(2-Pyridinyl)-N-[4-(1,4,8,11-tetraazacyclotetradecan-1-ylMethyl)benzyl]MethanaMine;AMD3465 R10406hexahydrobromide;N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide;AMD3465,98%;CS-810
28 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 5MG
  • 10
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0017248
  • Product descriptionAMD-3465 95.00%
  • Packaging5MG
  • Price$282.7
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3397
  • Product descriptionAMD3465hexahydrobromide
  • Packaging5mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3397
  • Product descriptionAMD3465hexahydrobromide
  • Packaging10mg
  • Price$156
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3397
  • Product descriptionAMD3465hexahydrobromide
  • Packaging50mg
  • Price$567
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3397
  • Product descriptionAMD3465hexahydrobromide
  • Packaging100mg
  • Price$914
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146242
  • Product descriptionAMD3465 >98%
  • Packaging100mg
  • Price$606.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146242
  • Product descriptionAMD3465 >98%
  • Packaging250mg
  • Price$912.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146242
  • Product descriptionAMD3465 >98%
  • Packaging1g
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11959
  • Product descriptionAMD 3465 (hydrobromide) ≥95%
  • Packaging5mg
  • Price$96
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11959
  • Product descriptionAMD 3465 (hydrobromide) ≥95%
  • Packaging10mg
  • Price$182
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11959
  • Product descriptionAMD 3465 (hydrobromide) ≥95%
  • Packaging25mg
  • Price$403
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2784
  • Product descriptionAMD3465(hexahydrobromide) 98.79%
  • Packaging5mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2784
  • Product descriptionAMD3465(hexahydrobromide) 98.79%
  • Packaging50mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002877
  • Product descriptionAMD3465hexahydrobromide 98+%
  • Packaging10mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002877
  • Product descriptionAMD3465hexahydrobromide 98+%
  • Packaging50mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002877
  • Product descriptionAMD3465hexahydrobromide 98+%
  • Packaging100mg
  • Price$280
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0017248 AMD-3465 95.00% 5MG $282.7 2021-12-16 Buy
ApexBio Technology B3397 AMD3465hexahydrobromide 5mg $123 2021-12-16 Buy
ApexBio Technology B3397 AMD3465hexahydrobromide 10mg $156 2021-12-16 Buy
ApexBio Technology B3397 AMD3465hexahydrobromide 50mg $567 2021-12-16 Buy
ApexBio Technology B3397 AMD3465hexahydrobromide 100mg $914 2021-12-16 Buy
Biorbyt Ltd orb146242 AMD3465 >98% 100mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb146242 AMD3465 >98% 250mg $912.9 2021-12-16 Buy
Biorbyt Ltd orb146242 AMD3465 >98% 1g $2245.7 2021-12-16 Buy
Cayman Chemical 11959 AMD 3465 (hydrobromide) ≥95% 5mg $96 2024-03-01 Buy
Cayman Chemical 11959 AMD 3465 (hydrobromide) ≥95% 10mg $182 2024-03-01 Buy
Cayman Chemical 11959 AMD 3465 (hydrobromide) ≥95% 25mg $403 2024-03-01 Buy
ChemScene CS-2784 AMD3465(hexahydrobromide) 98.79% 5mg $55 2021-12-16 Buy
ChemScene CS-2784 AMD3465(hexahydrobromide) 98.79% 50mg $260 2021-12-16 Buy
Crysdot CD31002877 AMD3465hexahydrobromide 98+% 10mg $59 2021-12-16 Buy
Crysdot CD31002877 AMD3465hexahydrobromide 98+% 50mg $154 2021-12-16 Buy
Crysdot CD31002877 AMD3465hexahydrobromide 98+% 100mg $280 2021-12-16 Buy

Properties

Melting point :>200°C (dec.)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Very Slightly), Water (Slightly)
form :powder
color :white to light brown

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

C-X-C chemokine receptor type 4 is a receptor for the stromal cell-derived factor-1 which is designated as chemokine ligand 12 (CXCL12). It is involved in cell progression, hematopoiesis, cancer, HIV entry, and rheumatoid arthritis. AMD 3465 blocks the cell surface binding of CXCL12 with an IC50 value of 18 nM. It inhibits CXCL12-induced calcium mobilization (IC50 = 4 nM) and at 6,250 nM completely blocks CXCL12-induced chemotaxis of SupT1 cells. AMD 3465 is active against various HIV strains with IC50 values ranging from 6 to 12 nM. It dose dependently inhibits eosinophil recruitment during type-2 granuloma formation and interferes with primary and secondary T-cell activation events in lymphoid tissue. At 50 μg/day, AMD 3465 blocks tumor growth and prevents CXCL12-induced cAMP suppression in xenograft models of medulloblastoma and glioblastoma.