MeriMepodib, VI-21497, VX-497
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- $32 - $2500
- Product name: MeriMepodib, VI-21497, VX-497
- CAS: 198821-22-6
- MF: C23H24N4O6
- MW: 452.46
- EINECS:-0
- MDL Number:MFCD09837807
- Synonyms:MeriMepodib, VI-21497, VX-497;[[3-[[[[3-Methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]carbamic acid (3S)-tetrahydro-3-furanyl ester;VI 21497;Carbamic acid, N-[[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-, (3S)-tetrahydro-3-furanyl ester;[(3S)-oxolan-3-yl] N-[[3-[[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]carbamoylamino]phenyl]methyl]carbamate;MERIMEPODIB; VX497; VX-497; VX 497; MMP; VI21497; VI-21497; VI 21497;(S)-Tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)benzylcarbamate;HCV,Inhibitor,Merimepodib,HBV,Hepatitis C virus,Hepatitis B virus,VX497,VX 497,inhibit,MMPD
28 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
Package
- 1mg
- 50mg
- 100mg
- 250mg
- 1g
- 2mg
- 5mg
- 25mg
- 10mM(in 1mL DMSO)
- 10mg
- ManufacturerAK Scientific
- Product number3810AH
- Product descriptionMerimepodib
- Packaging5mg
- Price$173
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA470058
- Product descriptionMerimepodib 98+%
- Packaging2mg
- Price$232
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA470058
- Product descriptionMerimepodib 98+%
- Packaging5mg
- Price$346
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA470058
- Product descriptionMerimepodib 98+%
- Packaging10mg
- Price$477
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA470058
- Product descriptionMerimepodib 98+%
- Packaging25mg
- Price$810
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1112
- Product descriptionMerimepodib
- Packaging2mg
- Price$217
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1112
- Product descriptionMerimepodib
- Packaging5mg
- Price$326
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1112
- Product descriptionMerimepodib
- Packaging10mg
- Price$465
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1112
- Product descriptionMerimepodib
- Packaging10mM(in 1mL DMSO)
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1112
- Product descriptionMerimepodib
- Packaging50mg
- Price$1395
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030013
- Product descriptionMerimepodib ≥98%
- Packaging5mg
- Price$343
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030013
- Product descriptionMerimepodib ≥98%
- Packaging2mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29351
- Product descriptionMerimepodib
- Packaging25mg
- Price$533
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29351
- Product descriptionMerimepodib
- Packaging10mg
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29351
- Product descriptionMerimepodib
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29351
- Product descriptionMerimepodib
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3810AH | Merimepodib | 5mg | $173 | 2021-12-16 | Buy |
| Ambeed | A470058 | Merimepodib 98+% | 2mg | $232 | 2021-12-16 | Buy |
| Ambeed | A470058 | Merimepodib 98+% | 5mg | $346 | 2021-12-16 | Buy |
| Ambeed | A470058 | Merimepodib 98+% | 10mg | $477 | 2021-12-16 | Buy |
| Ambeed | A470058 | Merimepodib 98+% | 25mg | $810 | 2021-12-16 | Buy |
| ApexBio Technology | B1112 | Merimepodib | 2mg | $217 | 2021-12-16 | Buy |
| ApexBio Technology | B1112 | Merimepodib | 5mg | $326 | 2021-12-16 | Buy |
| ApexBio Technology | B1112 | Merimepodib | 10mg | $465 | 2021-12-16 | Buy |
| ApexBio Technology | B1112 | Merimepodib | 10mM(in 1mL DMSO) | $470 | 2021-12-16 | Buy |
| ApexBio Technology | B1112 | Merimepodib | 50mg | $1395 | 2021-12-16 | Buy |
| Arctom | AS030013 | Merimepodib ≥98% | 5mg | $343 | 2021-12-16 | Buy |
| Arctom | AS030013 | Merimepodib ≥98% | 2mg | $230 | 2021-12-16 | Buy |
| Cayman Chemical | 29351 | Merimepodib | 25mg | $533 | 2024-03-01 | Buy |
| Cayman Chemical | 29351 | Merimepodib | 10mg | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 29351 | Merimepodib | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 29351 | Merimepodib | 1mg | $32 | 2024-03-01 | Buy |
Properties
Boiling point :571.4±50.0 °C(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :≥45.2 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :11.66±0.46(Predicted)
color :Off-white to light yellow
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :≥45.2 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :11.66±0.46(Predicted)
color :Off-white to light yellow
Safety Information
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Description
Merimepodib is an inhibitor of inosine-5''-monophosphate dehydrogenase (IMPDH; Kis = 7 and 10 nM for IMPDH type I and type II, respectively) with antiviral and immunosuppressant activities. It reduces Ebola, Lassa, chikungunya, Junin, and Zika virus titers in vitro and inhibits Zika virus replication in Huh7 cells (EC50 = 0.6 μM). Merimepodib inhibits the proliferation of PHA-stimulated T cells and SPAS-stimulated B cells (IC50s = 104 and 132 nM, respectively), effects that can be reversed by guanosine but not adenosine . In vivo, merimepodib (50 and 100 mg/kg) increases allograft survival in a murine skin transplantation model and prevents development of graft versus host disease (GVHD) in splenocyte allografted mice.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Baoji Guokang Bio-Technology Co., Ltd.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
Shanghai Acmec Biochemical Technology Co., Ltd.
