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ChemicalBook >> CAS DataBase List >> 1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE

1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE

1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE price.
  • $26 - $3728.1
  • Product name: 1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE
  • CAS: 202463-68-1
  • MF: C21H19Cl2IN4O2
  • MW: 557.21
  • EINECS:
  • MDL Number:MFCD01861180
  • Synonyms:AM-281 ,99%;1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE;AM 281;1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide AM 281;1H-Pyrazole-3-carboxamide,1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-;CS-1127;AM281;AM-281;1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholin-4-ylpyrazole-3-carboxamide
19 prices
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  • AK Scientific
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
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  • 10
  • 1mg
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  • ManufacturerAK Scientific
  • Product number1865BB
  • Product description1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1865BB
  • Product description1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide
  • Packaging10mg
  • Price$268
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6603
  • Product descriptionAM281
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6603
  • Product descriptionAM281
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6603
  • Product descriptionAM281
  • Packaging50mg
  • Price$505
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181102
  • Product descriptionAM 281 >98%
  • Packaging100mg
  • Price$950.3
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb181102
  • Product descriptionAM 281 >98%
  • Packaging250mg
  • Price$1876.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181102
  • Product descriptionAM 281 >98%
  • Packaging1000mg
  • Price$3728.1
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number10006972
  • Product descriptionAM281 ≥98%
  • Packaging1mg
  • Price$26
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number10006972
  • Product descriptionAM281 ≥98%
  • Packaging5mg
  • Price$78
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10006972
  • Product descriptionAM281 ≥98%
  • Packaging10mg
  • Price$143
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM163898
  • Product description1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholino-1H-pyrazole-3-carboxamide 95+%
  • Packaging10mg
  • Price$376
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM163898
  • Product description1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholino-1H-pyrazole-3-carboxamide 95+%
  • Packaging50mg
  • Price$1064
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM163898
  • Product description1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholino-1H-pyrazole-3-carboxamide 95+%
  • Packaging100mg
  • Price$1630
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7251
  • Product descriptionAM281 >98%
  • Packaging250mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA0980
  • Product descriptionAM281 ≥98% (HPLC)
  • Packaging10mg
  • Price$345
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1865BB 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide 1mg $133 2021-12-16 Buy
AK Scientific 1865BB 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide 10mg $268 2021-12-16 Buy
ApexBio Technology B6603 AM281 5mg $65 2021-12-16 Buy
ApexBio Technology B6603 AM281 10mg $125 2021-12-16 Buy
ApexBio Technology B6603 AM281 50mg $505 2021-12-16 Buy
Biorbyt Ltd orb181102 AM 281 >98% 100mg $950.3 2021-12-16 Buy
Biorbyt Ltd orb181102 AM 281 >98% 250mg $1876.8 2021-12-16 Buy
Biorbyt Ltd orb181102 AM 281 >98% 1000mg $3728.1 2021-12-16 Buy
Cayman Chemical 10006972 AM281 ≥98% 1mg $26 2024-03-01 Buy
Cayman Chemical 10006972 AM281 ≥98% 5mg $78 2024-03-01 Buy
Cayman Chemical 10006972 AM281 ≥98% 10mg $143 2024-03-01 Buy
Chemenu CM163898 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholino-1H-pyrazole-3-carboxamide 95+% 10mg $376 2021-12-16 Buy
Chemenu CM163898 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholino-1H-pyrazole-3-carboxamide 95+% 50mg $1064 2021-12-16 Buy
Chemenu CM163898 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholino-1H-pyrazole-3-carboxamide 95+% 100mg $1630 2021-12-16 Buy
DC Chemicals DC7251 AM281 >98% 250mg $750 2021-12-16 Buy
Sigma-Aldrich A0980 AM281 ≥98% (HPLC) 10mg $345 2024-03-01 Buy

Properties

Density :1.70±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >6 mg/mL
form :solid
pka :10.76±0.20(Predicted)
color :white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

AM 281 is a potent, selective analog of the cannabinoid receptor (CB1) antagonist SR 141716A. Potent CB1 ( CB1 receptor )antagonist/inverse agonist (Ki=14nM). AM 281 increases locomotor activity following systemic administration in vivo. Reported to be an analog of SR141716A.

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