Tebanicline (hydrochloride)
![]() |
- $37 - $870
- Product name: Tebanicline (hydrochloride)
- CAS: 203564-54-9
- MF: C9H12Cl2N2O
- MW: 235.11
- EINECS:
- MDL Number:
- Synonyms:Tebanicline (hydrochloride);Tebanicline HCl;ABT-594 (hydrochloride);(R)-5-(Azetidin-2-ylmethoxy)-2-chloropyridine hydrochloride;Ebanicline hydrochloride;EBANICLINE HYDROCHLORIDE; ABT594 HYDROCHLORIDE; ABT-594 HYDROCHLORIDE; ABT 594 HYDROCHLORIDE;Pyridine, 5-[(2R)-2-azetidinylmethoxy]-2-chloro-, hydrochloride (1:1);Pyridine, 5-[(2R)-2-azetidinylmethoxy]-2-chloro-, monohydrochloride
9 prices
Selected condition:
Brand
- AK Scientific
- Cayman Chemical
- DC Chemicals
- Tocris
- TRC
Package
- 10
- 1mg
- 5mg
- 50
- 10mg
- 25mg
- 100mg
- ManufacturerAK Scientific
- Product number0440DW
- Product descriptionTebanicline hydrochloride
- Packaging25mg
- Price$785
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22822
- Product descriptionABT-594 (hydrochloride)
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22822
- Product descriptionABT-594 (hydrochloride)
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22822
- Product descriptionABT-594 (hydrochloride)
- Packaging10mg
- Price$283
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22822
- Product descriptionABT-594 (hydrochloride)
- Packaging25mg
- Price$618
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC10331
- Product descriptionTebanicline hydrochloride >98%
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number6576
- Product descriptionABT594hydrochloride ≥98%(HPLC)
- Packaging10
- Price$207
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number6576
- Product descriptionABT594hydrochloride ≥98%(HPLC)
- Packaging50
- Price$870
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberA112650
- Product descriptionABT594Hydrochloride
- Packaging5mg
- Price$310
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 0440DW | Tebanicline hydrochloride | 25mg | $785 | 2021-12-16 | Buy |
Cayman Chemical | 22822 | ABT-594 (hydrochloride) | 1mg | $37 | 2024-03-01 | Buy |
Cayman Chemical | 22822 | ABT-594 (hydrochloride) | 5mg | $161 | 2024-03-01 | Buy |
Cayman Chemical | 22822 | ABT-594 (hydrochloride) | 10mg | $283 | 2024-03-01 | Buy |
Cayman Chemical | 22822 | ABT-594 (hydrochloride) | 25mg | $618 | 2024-03-01 | Buy |
DC Chemicals | DC10331 | Tebanicline hydrochloride >98% | 100mg | $450 | 2021-12-16 | Buy |
Tocris | 6576 | ABT594hydrochloride ≥98%(HPLC) | 10 | $207 | 2021-12-16 | Buy |
Tocris | 6576 | ABT594hydrochloride ≥98%(HPLC) | 50 | $870 | 2021-12-16 | Buy |
TRC | A112650 | ABT594Hydrochloride | 5mg | $310 | 2021-12-16 | Buy |
Properties
Melting point :116-117°
alpha :23D +8.6° (c = 0.52 in methanol)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A solid
alpha :23D +8.6° (c = 0.52 in methanol)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A solid
Safety Information
Symbol(GHS): | ||||||||
---|---|---|---|---|---|---|---|---|
Signal word: | ||||||||
Hazard statements: |
|
|||||||
Precautionary statements: |
|
Description
ABT-594 is a potent agonist of neuronal α4β2 subunit-containing nicotinic acetylcholine receptors (nAChRs; Ki = 37 pM in a radioligand binding assay). It is selective for neuronal nAChRs over neuromuscular α1β1δγ subunit-containing nAChRs (Ki = 10,000 nM), α1B-, α2B-, and α2C- adrenergic receptors (Kis = 890, 597, and 342 nM, respectively), and 70 other receptors, enzymes, and transporters (Kis = >1,000 nM) in radioligand binding assays. ABT-594 induces [86Rb+] efflux in K177 cells transfected with human neuronal α4β2 subunit-containing nAChRs (EC50 = 140 nM). In vivo, ABT-594 (0.05 and 0.01 mg/kg, s.c.) increases latency to paw withdrawal in a hot-plate test in rats. It also induces hypothermia, seizures, and an increase in blood pressure.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.
Jilin Chinese Academy of Sciences-yanshen Technology
Aladdin Scientific
MedChemexpress LLC
ShangHai Caerulum Pharma Discovery Co., Ltd.
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghai Chaolan Chemical Technology Center