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ChemicalBook >> CAS DataBase List >> Tebanicline (hydrochloride)

Tebanicline (hydrochloride)

Tebanicline (hydrochloride) price.
  • $37 - $870
  • Product name: Tebanicline (hydrochloride)
  • CAS: 203564-54-9
  • MF: C9H12Cl2N2O
  • MW: 235.11
  • EINECS:
  • MDL Number:
  • Synonyms:Tebanicline (hydrochloride);Tebanicline HCl;ABT-594 (hydrochloride);(R)-5-(Azetidin-2-ylmethoxy)-2-chloropyridine hydrochloride;Ebanicline hydrochloride;EBANICLINE HYDROCHLORIDE; ABT594 HYDROCHLORIDE; ABT-594 HYDROCHLORIDE; ABT 594 HYDROCHLORIDE;Pyridine, 5-[(2R)-2-azetidinylmethoxy]-2-chloro-, hydrochloride (1:1);Pyridine, 5-[(2R)-2-azetidinylmethoxy]-2-chloro-, monohydrochloride
9 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 10
  • 1mg
  • 5mg
  • 50
  • 10mg
  • 25mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number0440DW
  • Product descriptionTebanicline hydrochloride
  • Packaging25mg
  • Price$785
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22822
  • Product descriptionABT-594 (hydrochloride)
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22822
  • Product descriptionABT-594 (hydrochloride)
  • Packaging5mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22822
  • Product descriptionABT-594 (hydrochloride)
  • Packaging10mg
  • Price$283
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22822
  • Product descriptionABT-594 (hydrochloride)
  • Packaging25mg
  • Price$618
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10331
  • Product descriptionTebanicline hydrochloride >98%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number6576
  • Product descriptionABT594hydrochloride ≥98%(HPLC)
  • Packaging10
  • Price$207
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number6576
  • Product descriptionABT594hydrochloride ≥98%(HPLC)
  • Packaging50
  • Price$870
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberA112650
  • Product descriptionABT594Hydrochloride
  • Packaging5mg
  • Price$310
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0440DW Tebanicline hydrochloride 25mg $785 2021-12-16 Buy
Cayman Chemical 22822 ABT-594 (hydrochloride) 1mg $37 2024-03-01 Buy
Cayman Chemical 22822 ABT-594 (hydrochloride) 5mg $161 2024-03-01 Buy
Cayman Chemical 22822 ABT-594 (hydrochloride) 10mg $283 2024-03-01 Buy
Cayman Chemical 22822 ABT-594 (hydrochloride) 25mg $618 2024-03-01 Buy
DC Chemicals DC10331 Tebanicline hydrochloride >98% 100mg $450 2021-12-16 Buy
Tocris 6576 ABT594hydrochloride ≥98%(HPLC) 10 $207 2021-12-16 Buy
Tocris 6576 ABT594hydrochloride ≥98%(HPLC) 50 $870 2021-12-16 Buy
TRC A112650 ABT594Hydrochloride 5mg $310 2021-12-16 Buy

Properties

Melting point :116-117°
alpha :23D +8.6° (c = 0.52 in methanol)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

ABT-594 is a potent agonist of neuronal α4β2 subunit-containing nicotinic acetylcholine receptors (nAChRs; Ki = 37 pM in a radioligand binding assay). It is selective for neuronal nAChRs over neuromuscular α1β1δγ subunit-containing nAChRs (Ki = 10,000 nM), α1B-, α2B-, and α2C- adrenergic receptors (Kis = 890, 597, and 342 nM, respectively), and 70 other receptors, enzymes, and transporters (Kis = >1,000 nM) in radioligand binding assays. ABT-594 induces [86Rb+] efflux in K177 cells transfected with human neuronal α4β2 subunit-containing nAChRs (EC50 = 140 nM). In vivo, ABT-594 (0.05 and 0.01 mg/kg, s.c.) increases latency to paw withdrawal in a hot-plate test in rats. It also induces hypothermia, seizures, and an increase in blood pressure.