6,7-DIHYDRO-3-[(2-HYDROXYETHYL)THIO]-6,6-DIMETHYL-1-(2-THIAZOLYL)-BENZO[C]THIOPHEN-4(5H)-ONE
![6,7-DIHYDRO-3-[(2-HYDROXYETHYL)THIO]-6,6-DIMETHYL-1-(2-THIAZOLYL)-BENZO[C]THIOPHEN-4(5H)-ONE price.](/CAS/GIF/207306-50-1.gif)
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- $88.5 - $752
- Product name: 6,7-DIHYDRO-3-[(2-HYDROXYETHYL)THIO]-6,6-DIMETHYL-1-(2-THIAZOLYL)-BENZO[C]THIOPHEN-4(5H)-ONE
- CAS: 207306-50-1
- MF: C15H17NO2S3
- MW: 339.5
- EINECS:
- MDL Number:MFCD10687100
- Synonyms:6,7-DIHYDRO-3-[(2-HYDROXYETHYL)THIO]-6,6-DIMETHYL-1-(2-THIAZOLYL)-BENZO[C]THIOPHEN-4(5H)-ONE;TB 21007;3-(2-hydroxyethylsulfanyl)-6,6-dimethyl-1-(1,3-thiazol-2-yl)-5,7-dihydro-2-benzothiophen-4-one;Benzo[c]thiophen-4(5H)-one, 6,7-dihydro-3-[(2-hydroxyethyl)thio]-6,6-dimethyl-1-(2-thiazolyl)-
13 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 5mg
- 10mg
- 10
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product number4574CQ
- Product description3-(2-Hydroxyethylsulfanyl)-6,6-dimethyl-1-(1,3-thiazol-2-yl)-5,7-dihydro-2-benzothiophen-4-one
- Packaging5mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4574CQ
- Product description3-(2-Hydroxyethylsulfanyl)-6,6-dimethyl-1-(1,3-thiazol-2-yl)-5,7-dihydro-2-benzothiophen-4-one
- Packaging10mg
- Price$316
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7214
- Product descriptionTB21007
- Packaging10mg
- Price$266
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27674
- Product descriptionTB 21007
- Packaging5mg
- Price$110
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27674
- Product descriptionTB 21007
- Packaging10mg
- Price$195
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27674
- Product descriptionTB 21007
- Packaging25mg
- Price$459
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML3300
- Product descriptionTB21007 ≥98% (HPLC)
- Packaging5MG
- Price$88.5
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML3300
- Product descriptionTB21007 ≥98% (HPLC)
- Packaging25MG
- Price$374
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number2905
- Product descriptionTB21007 ≥99%(HPLC)
- Packaging10
- Price$179
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number2905
- Product descriptionTB21007 ≥99%(HPLC)
- Packaging50
- Price$752
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberT296373
- Product descriptionTB21007
- Packaging10mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberT296373
- Product descriptionTB21007
- Packaging50mg
- Price$715
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number256816
- Product descriptionTB 21007
- Packaging10mg
- Price$432
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4574CQ | 3-(2-Hydroxyethylsulfanyl)-6,6-dimethyl-1-(1,3-thiazol-2-yl)-5,7-dihydro-2-benzothiophen-4-one | 5mg | $220 | 2021-12-16 | Buy |
| AK Scientific | 4574CQ | 3-(2-Hydroxyethylsulfanyl)-6,6-dimethyl-1-(1,3-thiazol-2-yl)-5,7-dihydro-2-benzothiophen-4-one | 10mg | $316 | 2021-12-16 | Buy |
| ApexBio Technology | B7214 | TB21007 | 10mg | $266 | 2021-12-16 | Buy |
| Cayman Chemical | 27674 | TB 21007 | 5mg | $110 | 2024-03-01 | Buy |
| Cayman Chemical | 27674 | TB 21007 | 10mg | $195 | 2024-03-01 | Buy |
| Cayman Chemical | 27674 | TB 21007 | 25mg | $459 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML3300 | TB21007 ≥98% (HPLC) | 5MG | $88.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML3300 | TB21007 ≥98% (HPLC) | 25MG | $374 | 2024-03-01 | Buy |
| Tocris | 2905 | TB21007 ≥99%(HPLC) | 10 | $179 | 2021-12-16 | Buy |
| Tocris | 2905 | TB21007 ≥99%(HPLC) | 50 | $752 | 2021-12-16 | Buy |
| TRC | T296373 | TB21007 | 10mg | $170 | 2021-12-16 | Buy |
| TRC | T296373 | TB21007 | 50mg | $715 | 2021-12-16 | Buy |
| Usbiological | 256816 | TB 21007 | 10mg | $432 | 2021-12-16 | Buy |
Properties
Melting point :175-177 °C
Boiling point :544.9±60.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: 100 mM; Ethanol: 25 mM
form :A solid
pka :14.22±0.10(Predicted)
Boiling point :544.9±60.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: 100 mM; Ethanol: 25 mM
form :A solid
pka :14.22±0.10(Predicted)
Safety Information
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Description
TB 21007 is an inverse agonist of α5β3γ2 subunit-containing GABAA receptors (Ki = 1.6 nM). It selectively inhibits α5β3γ2 subunit-containing GABAA receptors over α1-4 and α6 subunit-containing GABAA receptors that also contain β3 and γ2 subunits (Kis = 20, 16, 20, 106, and 1,800 nM, respectively). TB 21007 reduces the latency to find the hidden platform in a matching-to-place variant of the Morris water maze, indicating enhanced spatial memory, in rats when administered at a dose of 0.3 mg/kg. It reduces paw tactile allodynia induced by reserpine in a rat model of fibromyalgia-like pain when administered intrathecally at doses of 1.5, 15, and 150 nmol.More related product prices
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