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ChemicalBook >> CAS DataBase List >> 9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC-3,3,4,4-D4 ACID

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC-3,3,4,4-D4 ACID

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC-3,3,4,4-D4 ACID price.
4 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 25μg
  • 50μg
  • 100μg
  • 10 μg
  • ManufacturerCayman Chemical
  • Product number10007272
  • Product descriptionProstaglandin D2-d4 MaxSpec® Standard ≥95%
  • Packaging10 μg
  • Price$138
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number312010
  • Product descriptionProstaglandin D2-d4 ≥99% deuterated forms (d1-d4)
  • Packaging100μg
  • Price$330
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number312010
  • Product descriptionProstaglandin D2-d4 ≥99% deuterated forms (d1-d4)
  • Packaging50μg
  • Price$176
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number312010
  • Product descriptionProstaglandin D2-d4 ≥99% deuterated forms (d1-d4)
  • Packaging25μg
  • Price$93
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 10007272 Prostaglandin D2-d4 MaxSpec® Standard ≥95% 10 μg $138 2023-06-20 Buy
Cayman Chemical 312010 Prostaglandin D2-d4 ≥99% deuterated forms (d1-d4) 100μg $330 2024-03-01 Buy
Cayman Chemical 312010 Prostaglandin D2-d4 ≥99% deuterated forms (d1-d4) 50μg $176 2024-03-01 Buy
Cayman Chemical 312010 Prostaglandin D2-d4 ≥99% deuterated forms (d1-d4) 25μg $93 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: >100 mg/ml (from PGD2),DMSO: >50 mg/ml (from PGD2),Ethanol: >75 mg/ml (from PGD2),PBS pH 7.2: >5 mg/ml (from PGD2)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Prostaglandin D2-d4 (PGD2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry. PGD2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as β-trace.2,3 In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 inhibits human ovarian tumor cell proliferation with an IC50 of 6.8 μM.