(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL
- $41 - $2986.9
- Product name: (2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL
- CAS: 212844-54-7
- MF: C20H25ClN6O3
- MW: 432.9
- EINECS:
- MDL Number:MFCD04118312
- Synonyms:(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL;PURVALANOL B;NG 95;(2R)-2-((6-((3-Chloro-4-carboxyphenyl)amino)-9-(1-methylethyl)-9H-purin-2-yl)amino)-3-methyl-1-butanol;NG 95, (2R)-2-[[6-[(3-Chloro-4-carboxyphenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol;Purvalanol B, >=96%;(R)-2-Chloro-4-((2-((1-hydroxy-3-methylbutan-2-yl)amino)-9-isopropyl-9H-purin-6-yl)amino)benzo;Purvalanol B(NG 95)
34 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
Package
- 2mg
- 50
- 1mg
- 10
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 10mM(in 1mL DMSO)
- 1000mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1070-M001
- Product descriptionPurvalanol B ≥95%
- Packaging1mg
- Price$54
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3984AH
- Product descriptionPurvalanol B
- Packaging10mg
- Price$159
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA176253
- Product descriptionPurvalanol B 98+%
- Packaging2mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA176253
- Product descriptionPurvalanol B 98+%
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA176253
- Product descriptionPurvalanol B 98+%
- Packaging10mg
- Price$117
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA176253
- Product descriptionPurvalanol B 98+%
- Packaging50mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000206
- Product descriptionPURVALANOL B 95.00%
- Packaging1MG
- Price$166.95
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000206
- Product descriptionPURVALANOL B 95.00%
- Packaging10MG
- Price$745.85
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000206
- Product descriptionPURVALANOL B 95.00%
- Packaging50MG
- Price$1417.71
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8565
- Product descriptionPurvalanol B
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8565
- Product descriptionPurvalanol B
- Packaging10mM(in 1mL DMSO)
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8565
- Product descriptionPurvalanol B
- Packaging50mg
- Price$448
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS032175
- Product descriptionPurvalanol B
- Packaging2mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS032175
- Product descriptionPurvalanol B
- Packaging5mg
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181107
- Product descriptionPurvalanol B(NG-95) >98%
- Packaging100mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181107
- Product descriptionPurvalanol B(NG-95) >98%
- Packaging250mg
- Price$1504.5
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | SYN-1070-M001 | Purvalanol B ≥95% | 1mg | $54 | 2021-12-16 | Buy |
AK Scientific | 3984AH | Purvalanol B | 10mg | $159 | 2021-12-16 | Buy |
Ambeed | A176253 | Purvalanol B 98+% | 2mg | $51 | 2021-12-16 | Buy |
Ambeed | A176253 | Purvalanol B 98+% | 5mg | $90 | 2021-12-16 | Buy |
Ambeed | A176253 | Purvalanol B 98+% | 10mg | $117 | 2021-12-16 | Buy |
Ambeed | A176253 | Purvalanol B 98+% | 50mg | $198 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000206 | PURVALANOL B 95.00% | 1MG | $166.95 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000206 | PURVALANOL B 95.00% | 10MG | $745.85 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000206 | PURVALANOL B 95.00% | 50MG | $1417.71 | 2021-12-16 | Buy |
ApexBio Technology | A8565 | Purvalanol B | 10mg | $95 | 2021-12-16 | Buy |
ApexBio Technology | A8565 | Purvalanol B | 10mM(in 1mL DMSO) | $132 | 2021-12-16 | Buy |
ApexBio Technology | A8565 | Purvalanol B | 50mg | $448 | 2021-12-16 | Buy |
Arctom | AS032175 | Purvalanol B | 2mg | $50 | 2021-12-16 | Buy |
Arctom | AS032175 | Purvalanol B | 5mg | $89 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181107 | Purvalanol B(NG-95) >98% | 100mg | $765 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181107 | Purvalanol B(NG-95) >98% | 250mg | $1504.5 | 2021-12-16 | Buy |
Properties
Melting point :58.5 °C
Boiling point :660.6±65.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 37 mg/mL, soluble
form :solid
pka :2.81±0.25(Predicted)
color :White to light yellow
InChIKey :ZKDXRFMOHZVXSG-HNNXBMFYSA-N
Boiling point :660.6±65.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 37 mg/mL, soluble
form :solid
pka :2.81±0.25(Predicted)
color :White to light yellow
InChIKey :ZKDXRFMOHZVXSG-HNNXBMFYSA-N
Safety Information
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Description
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Purvalanol B is a CDK inhibitor that most potently inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively). It is inactive against Cdk4/cyclin D1 as well as several other protein kinases. Purvalanol B is a 2,6,9-trisubstituted purine that, at micromolar doses, inhibits the growth of parasites, including Plasmodium.Related product price
- PURVALANOL A
$22-1800 - N,N-DIETHYLBENZAMIDE
$10-747 - Permethrin
$37-2200
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$6.60 /1KG
(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL CAS:212844-54-7
(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL CAS:212844-54-7