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ChemicalBook >> CAS DataBase List >> 7-CYCLOPENTYL-5-(4-PHENOXY)PHENYL-7H-PYR

7-CYCLOPENTYL-5-(4-PHENOXY)PHENYL-7H-PYR

7-CYCLOPENTYL-5-(4-PHENOXY)PHENYL-7H-PYR price.
  • $50 - $3282.7
  • Product name: 7-CYCLOPENTYL-5-(4-PHENOXY)PHENYL-7H-PYR
  • CAS: 213743-31-8
  • MF: C23H22N4O
  • MW: 370.45
  • EINECS:
  • MDL Number:MFCD04974490
  • Synonyms:7-CYCLOPENTYL-5-(4-PHENOXY)PHENYL-7H-PYR;7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine;RK-24466 ;RK 24466 ;RK24466;Lck Inhibitor - CAS 213743-31-8 - Calbiochem;d]pyrimidin-4-ylamine;RK-24466;KIN 001-51;7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-cyclopentyl-5-(4-phenoxyphenyl)-
21 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 1MG
  • 5mg
  • 10mg
  • 25MG
  • 100mg
  • 250mg
  • 1g
  • 500 μg
  • ManufacturerAK Scientific
  • Product number0013CQ
  • Product description4-Amino-5-(4-Phenoxyphenyl)-7h-Pyrrolo[2,3-D]pyrimidin-7-Yl-Cyclopentane
  • Packaging250mg
  • Price$814
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA724479
  • Product descriptionRK-24466 98+%
  • Packaging5mg
  • Price$278
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCOR0003693
  • Product description7-CYCLOPENTYL-5-(4-PHENOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YLAMINE 95.00%
  • Packaging1MG
  • Price$197.4
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCOR0003693
  • Product description7-CYCLOPENTYL-5-(4-PHENOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YLAMINE 95.00%
  • Packaging5MG
  • Price$713.38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCOR0003693
  • Product description7-CYCLOPENTYL-5-(4-PHENOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YLAMINE 95.00%
  • Packaging25MG
  • Price$1085.42
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573013
  • Product descriptionRK-24466 >98%
  • Packaging100mg
  • Price$912.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573013
  • Product descriptionRK-24466 >98%
  • Packaging250mg
  • Price$1654.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573013
  • Product descriptionRK-24466 >98%
  • Packaging1g
  • Price$3282.7
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15135
  • Product descriptionLCK Inhibitor ≥95%
  • Packaging500 μg
  • Price$50
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15135
  • Product descriptionLck Inhibitor ≥95%
  • Packaging1mg
  • Price$95
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15135
  • Product descriptionLck Inhibitor ≥95%
  • Packaging5mg
  • Price$198
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15135
  • Product descriptionLCK Inhibitor ≥95%
  • Packaging10mg
  • Price$346
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15135
  • Product descriptionLCK Inhibitor ≥95%
  • Packaging25mg
  • Price$609
  • Updated2022-04-27
  • Buy
  • ManufacturerChemScene
  • Product numberCS-8050
  • Product descriptionRK-24466 99.14%
  • Packaging1mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-8050
  • Product descriptionRK-24466 99.14%
  • Packaging5mg
  • Price$276
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN23720
  • Product descriptionRK24466
  • Packaging1mg
  • Price$106
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0013CQ 4-Amino-5-(4-Phenoxyphenyl)-7h-Pyrrolo[2,3-D]pyrimidin-7-Yl-Cyclopentane 250mg $814 2021-12-16 Buy
Ambeed A724479 RK-24466 98+% 5mg $278 2021-12-16 Buy
American Custom Chemicals Corporation COR0003693 7-CYCLOPENTYL-5-(4-PHENOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YLAMINE 95.00% 1MG $197.4 2021-12-16 Buy
American Custom Chemicals Corporation COR0003693 7-CYCLOPENTYL-5-(4-PHENOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YLAMINE 95.00% 5MG $713.38 2021-12-16 Buy
American Custom Chemicals Corporation COR0003693 7-CYCLOPENTYL-5-(4-PHENOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YLAMINE 95.00% 25MG $1085.42 2021-12-16 Buy
Biorbyt Ltd orb573013 RK-24466 >98% 100mg $912.9 2021-12-16 Buy
Biorbyt Ltd orb573013 RK-24466 >98% 250mg $1654.1 2021-12-16 Buy
Biorbyt Ltd orb573013 RK-24466 >98% 1g $3282.7 2021-12-16 Buy
Cayman Chemical 15135 LCK Inhibitor ≥95% 500 μg $50 2024-03-01 Buy
Cayman Chemical 15135 Lck Inhibitor ≥95% 1mg $95 2024-03-01 Buy
Cayman Chemical 15135 Lck Inhibitor ≥95% 5mg $198 2024-03-01 Buy
Cayman Chemical 15135 LCK Inhibitor ≥95% 10mg $346 2024-03-01 Buy
Cayman Chemical 15135 LCK Inhibitor ≥95% 25mg $609 2022-04-27 Buy
ChemScene CS-8050 RK-24466 99.14% 1mg $132 2021-12-16 Buy
ChemScene CS-8050 RK-24466 99.14% 5mg $276 2021-12-16 Buy
CSNpharm CSN23720 RK24466 1mg $106 2021-12-16 Buy

Properties

Boiling point :605.1±55.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 17 mg/mL at ≤60 °C, soluble
pka :5.75±0.30(Predicted)
form :White solid
color :white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Lymphocyte-speci?c protein tyrosine kinase (Lck) is a member of the Src-family of non-receptor protein tyrosine kinases and plays a critical role in the initial steps of T cell receptor signaling that trigger the production of cytokines. Lck inhibitor is a pyrrolopyrimidine that blocks the activity of two forms of Lck kinase, Lck (64-509) and Lckcd, with IC50 values of <1 and 2 nM, respectively. It inhibits the related kinases Src, Kdr, and Tie-2 with much weaker potency (IC50s = 70 nM, 1.57, and 1.98 μM, respectively) and only minimally inhibits the activities of EGFR, PKC, CDC2/B and ZAP-70 (IC50s = 3.2, >33, >50, and >50 μM, respectively). This compound has been shown to inhibit T cell receptor-stimulated IL-2 production in mice (ED50s = 4 and 25 mg/kg when administered either i.p. or orally).