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ChemicalBook >> CAS DataBase List >> 5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE

5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE

5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE price.
  • $50 - $1100
  • Product name: 5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE
  • CAS: 218457-67-1
  • MF: C15H18N2O
  • MW: 242.32
  • EINECS:
  • MDL Number:MFCD00052647
  • Synonyms:6-[4-(tert-Butyl)phenoxy]pyridin-3-amine 97%;6-[4-(tert-Butyl)phenoxy]pyridin-3-amine97%;5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE;6-[4-(TERT-BUTYL)PHENOXY]PYRIDIN-3-AMINE;BUTTPARK 96\12-100;3-Pyridinamine, 6-[4-(1,1-dimethylethyl)phenoxy]-;6-(4-tert-butylphenoxy)-3-pyridinamine;pathway,CB103,inhibit,Inhibitor,Notch,CB-103,signaling,leukemia,CB 103
20 prices
Selected condition:
Brand
  • AHH
  • Alichem
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TRC
Package
  • 50mg
  • 100mg
  • 001
  • 10mg
  • 003
  • 500mg
  • 1G
  • 5g
  • 10g
  • 100g
  • ManufacturerAHH
  • Product numberMT-43985
  • Product description5-Amino-2-(4-tert-butylphenoxy)pyridine 97%
  • Packaging100g
  • Price$710
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number218457671
  • Product description6-(4-(tert-Butyl)phenoxy)pyridin-3-amine
  • Packaging5g
  • Price$245.92
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number218457671
  • Product description6-(4-(tert-Butyl)phenoxy)pyridin-3-amine
  • Packaging10g
  • Price$376.32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0027012
  • Product description5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE 95.00%
  • Packaging1G
  • Price$661.22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0027012
  • Product description5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE 95.00%
  • Packaging5G
  • Price$933.45
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR8051
  • Product description6-[4-(tert-Butyl)phenoxy]pyridin-3-amine 97%
  • Packaging1g
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR8051
  • Product description6-[4-(tert-Butyl)phenoxy]pyridin-3-amine 97%
  • Packaging5g
  • Price$244
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM171363
  • Product description6-(4-(tert-butyl)phenoxy)pyridin-3-amine 95%
  • Packaging10g
  • Price$445
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0109594
  • Product descriptionCB-103 99.77%
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0109594
  • Product descriptionCB-103 99.77%
  • Packaging50mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0109594
  • Product descriptionCB-103 99.77%
  • Packaging100mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11164759
  • Product description6-(4-(tert-Butyl)phenoxy)pyridin-3-amine 95+%
  • Packaging10g
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product number012826
  • Product descriptionCB-103
  • Packaging001
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product number012826
  • Product descriptionCB-103
  • Packaging003
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML3460
  • Product descriptionCB-103 ≥97% (HPLC)
  • Packaging10MG
  • Price$64.8
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML3460
  • Product descriptionCB-103 ≥97% (HPLC)
  • Packaging50MG
  • Price$261
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-43985 5-Amino-2-(4-tert-butylphenoxy)pyridine 97% 100g $710 2021-12-16 Buy
Alichem 218457671 6-(4-(tert-Butyl)phenoxy)pyridin-3-amine 5g $245.92 2021-12-16 Buy
Alichem 218457671 6-(4-(tert-Butyl)phenoxy)pyridin-3-amine 10g $376.32 2021-12-16 Buy
American Custom Chemicals Corporation CHM0027012 5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE 95.00% 1G $661.22 2021-12-16 Buy
American Custom Chemicals Corporation CHM0027012 5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE 95.00% 5G $933.45 2021-12-16 Buy
Apolloscientific OR8051 6-[4-(tert-Butyl)phenoxy]pyridin-3-amine 97% 1g $105 2021-12-16 Buy
Apolloscientific OR8051 6-[4-(tert-Butyl)phenoxy]pyridin-3-amine 97% 5g $244 2021-12-16 Buy
Chemenu CM171363 6-(4-(tert-butyl)phenoxy)pyridin-3-amine 95% 10g $445 2021-12-16 Buy
ChemScene CS-0109594 CB-103 99.77% 10mg $50 2021-12-16 Buy
ChemScene CS-0109594 CB-103 99.77% 50mg $60 2021-12-16 Buy
ChemScene CS-0109594 CB-103 99.77% 100mg $70 2021-12-16 Buy
Crysdot CD11164759 6-(4-(tert-Butyl)phenoxy)pyridin-3-amine 95+% 10g $470 2021-12-16 Buy
DC Chemicals 012826 CB-103 001 $300 2021-12-16 Buy
DC Chemicals 012826 CB-103 003 $1100 2021-12-16 Buy
Sigma-Aldrich SML3460 CB-103 ≥97% (HPLC) 10MG $64.8 2024-03-01 Buy
Sigma-Aldrich SML3460 CB-103 ≥97% (HPLC) 50MG $261 2024-03-01 Buy

Properties

Melting point :89-90
storage temp. :2-8°C
solubility :Soluble in DMSO (>30 mg/ml)
form :solid
color :Off-white to pale orange
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :218457-67-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

CB-103 (218457-67-1) is an orally active inhibitor of the Notch signaling activation complex (IC50’s from 0.9 to 3.9 μM in various cell-based assays), the most downstream level of the Notch signaling pathway. It inhibited the growth of Notch-addicted human T cell acute lymphoblastic leukemia cells as well as other cell lines.? CB-103 also inhibited the growth of human breast cancer and leukemia xenografts without the intestinal toxicity associated with γ-secretase Notch inhibitors.

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