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ChemicalBook >> CAS DataBase List >> BIS(4-HYDROXYCINNAMOYL)METHANE

BIS(4-HYDROXYCINNAMOYL)METHANE

BIS(4-HYDROXYCINNAMOYL)METHANE price.
  • $45 - $4861.92
  • Product name: BIS(4-HYDROXYCINNAMOYL)METHANE
  • CAS: 24939-16-0
  • MF: C19H16O4
  • MW: 308.33
  • EINECS:607-464-9
  • MDL Number:MFCD03419284
  • Synonyms:BIS-DESMETHOXYCURCUMIN;BIS(4-HYDROXYCINNAMOYL)METHANE;DEMETHOXYCURCUMIN, BIS-;CURCUMIN 3;(1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione;BIS-(PARA-HYDROXYCINNAMOYL)METHANE;CURCUMINIII;1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
23 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chem-Impex
  • Crysdot
  • DC Chemicals
  • TCI Chemical
  • TRC
Package
  • 5mg
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 10G
  • 25g
  • 50G
  • 250G
  • ManufacturerAK Scientific
  • Product number4846BA
  • Product description1,7-Bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
  • Packaging25g
  • Price$365
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberFFG0000078
  • Product descriptionBIS(4-HYDROXYCINNAMOYL)METHANE 95.00%
  • Packaging10G
  • Price$1129.08
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberFFG0000078
  • Product descriptionBIS(4-HYDROXYCINNAMOYL)METHANE 95.00%
  • Packaging50G
  • Price$2573.46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberFFG0000078
  • Product descriptionBIS(4-HYDROXYCINNAMOYL)METHANE 95.00%
  • Packaging250G
  • Price$4861.92
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1712
  • Product descriptionBisdemethoxycurcumin
  • Packaging20mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS610905
  • Product descriptionBisdemethoxycucurmin ≥98%
  • Packaging1g
  • Price$47
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS610905
  • Product descriptionBisdemethoxycucurmin ≥98%
  • Packaging5g
  • Price$136
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS610905
  • Product descriptionBisdemethoxycucurmin ≥98%
  • Packaging25g
  • Price$403
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10960
  • Product descriptionBisdemethoxycurcumin ≥98%
  • Packaging5mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10960
  • Product descriptionBisdemethoxycurcumin ≥98%
  • Packaging10mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10960
  • Product descriptionBisdemethoxycurcumin ≥98%
  • Packaging25mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10960
  • Product descriptionBisdemethoxycurcumin ≥98%
  • Packaging50mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number42428
  • Product descriptionBisdemethoxycurcumin,98%(HPLC) 98%(HPLC)
  • Packaging5G
  • Price$71.68
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number42428
  • Product descriptionBisdemethoxycurcumin,98%(HPLC) 98%(HPLC)
  • Packaging25G
  • Price$248.64
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD32001842
  • Product descriptionBisdemethoxycurcumin(RandomConfiguration) 95+%
  • Packaging100mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD32001842
  • Product descriptionBisdemethoxycurcumin(RandomConfiguration) 95+%
  • Packaging250mg
  • Price$110
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4846BA 1,7-Bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione 25g $365 2021-12-16 Buy
American Custom Chemicals Corporation FFG0000078 BIS(4-HYDROXYCINNAMOYL)METHANE 95.00% 10G $1129.08 2021-12-16 Buy
American Custom Chemicals Corporation FFG0000078 BIS(4-HYDROXYCINNAMOYL)METHANE 95.00% 50G $2573.46 2021-12-16 Buy
American Custom Chemicals Corporation FFG0000078 BIS(4-HYDROXYCINNAMOYL)METHANE 95.00% 250G $4861.92 2021-12-16 Buy
ApexBio Technology N1712 Bisdemethoxycurcumin 20mg $200 2021-12-16 Buy
Arctom AS610905 Bisdemethoxycucurmin ≥98% 1g $47 2021-12-16 Buy
Arctom AS610905 Bisdemethoxycucurmin ≥98% 5g $136 2021-12-16 Buy
Arctom AS610905 Bisdemethoxycucurmin ≥98% 25g $403 2021-12-16 Buy
Cayman Chemical 10960 Bisdemethoxycurcumin ≥98% 5mg $45 2021-12-16 Buy
Cayman Chemical 10960 Bisdemethoxycurcumin ≥98% 10mg $86 2021-12-16 Buy
Cayman Chemical 10960 Bisdemethoxycurcumin ≥98% 25mg $124 2021-12-16 Buy
Cayman Chemical 10960 Bisdemethoxycurcumin ≥98% 50mg $225 2021-12-16 Buy
Chem-Impex 42428 Bisdemethoxycurcumin,98%(HPLC) 98%(HPLC) 5G $71.68 2021-12-16 Buy
Chem-Impex 42428 Bisdemethoxycurcumin,98%(HPLC) 98%(HPLC) 25G $248.64 2021-12-16 Buy
Crysdot CD32001842 Bisdemethoxycurcumin(RandomConfiguration) 95+% 100mg $70 2021-12-16 Buy
Crysdot CD32001842 Bisdemethoxycurcumin(RandomConfiguration) 95+% 250mg $110 2021-12-16 Buy

Properties

Melting point :91-93℃
Boiling point :551.3±45.0 °C(Predicted)
Density :1.285
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
pka :8.67±0.46(Predicted)
form :Solid
color :Light yellow to Brown
Stability :Light Sensitive
InChIKey :PREBVFJICNPEKM-YDWXAUTNSA-N
LogP :3.155 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Bisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α,25-dihydroxyvitamin D3 to stimulate amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC). More stable than curcumin in physiological media, BDMC suppresses proliferation in cancer cells. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits LPS induction of iNOS expression.

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