2 - (4 - Methylphenyl) - 1,2 - benzisothiazol - 3(2H)-one
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- $37 - $1200
- Product name: 2 - (4 - Methylphenyl) - 1,2 - benzisothiazol - 3(2H)-one
- CAS: 2514-30-9
- MF: C14H11NOS
- MW: 241.31
- EINECS:604-604-1
- MDL Number:MFCD05856231
- Synonyms:2 - (4 - Methylphenyl) - 1,2 - benzisothiazol - 3(2H)-one;2-(4-Methylphenyl)-2,3-dihydrobenzisothiazol-3-one;2-p-Tolyl-1,2-benzisothiazolin-3-one;PBIT;PBIT, >=98%;JUMONJI HDM INHIBITOR;CS-1495;2-(4-methylphenyl)-1,2-benzothiazol-3-one
20 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 250mg
- 0.500g
- 1g
- ManufacturerAK Scientific
- Product numberY1896
- Product description2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one
- Packaging25mg
- Price$491
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3584
- Product descriptionPBIT
- Packaging5mg
- Price$102
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3584
- Product descriptionPBIT
- Packaging10mg
- Price$182
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3584
- Product descriptionPBIT
- Packaging25mg
- Price$402
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545928
- Product descriptionPbIT >98%
- Packaging5mg
- Price$161.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545928
- Product descriptionPbIT >98%
- Packaging25mg
- Price$416.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16272
- Product descriptionPBIT ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16272
- Product descriptionPBIT ≥98%
- Packaging5mg
- Price$90
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16272
- Product descriptionPBIT ≥98%
- Packaging10mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16272
- Product descriptionPBIT ≥98%
- Packaging25mg
- Price$353
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0021365
- Product descriptionPBIT 98.30%
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0021365
- Product descriptionPBIT 98.30%
- Packaging10mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0021365
- Product descriptionPBIT 98.30%
- Packaging50mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11158823
- Product description2-(p-Tolyl)benzo[d]isothiazol-3(2H)-one 95+%
- Packaging1g
- Price$465
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7550
- Product descriptionPBIT >98%
- Packaging250mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7550
- Product descriptionPBIT >98%
- Packaging1g
- Price$1200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y1896 | 2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | 25mg | $491 | 2021-12-16 | Buy |
| ApexBio Technology | C3584 | PBIT | 5mg | $102 | 2021-12-16 | Buy |
| ApexBio Technology | C3584 | PBIT | 10mg | $182 | 2021-12-16 | Buy |
| ApexBio Technology | C3584 | PBIT | 25mg | $402 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545928 | PbIT >98% | 5mg | $161.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545928 | PbIT >98% | 25mg | $416.5 | 2021-12-16 | Buy |
| Cayman Chemical | 16272 | PBIT ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 16272 | PBIT ≥98% | 5mg | $90 | 2024-03-01 | Buy |
| Cayman Chemical | 16272 | PBIT ≥98% | 10mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 16272 | PBIT ≥98% | 25mg | $353 | 2024-03-01 | Buy |
| ChemScene | CS-0021365 | PBIT 98.30% | 5mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-0021365 | PBIT 98.30% | 10mg | $220 | 2021-12-16 | Buy |
| ChemScene | CS-0021365 | PBIT 98.30% | 50mg | $750 | 2021-12-16 | Buy |
| Crysdot | CD11158823 | 2-(p-Tolyl)benzo[d]isothiazol-3(2H)-one 95+% | 1g | $465 | 2021-12-16 | Buy |
| DC Chemicals | DC7550 | PBIT >98% | 250mg | $650 | 2021-12-16 | Buy |
| DC Chemicals | DC7550 | PBIT >98% | 1g | $1200 | 2021-12-16 | Buy |
Properties
Melting point :136.7-137.1 °C(Solv: benzene (71-43-2); hexane (110-54-3))
Boiling point :418.2±38.0 °C(Predicted)
Density :1.297±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
pka :-0.03±0.20(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Boiling point :418.2±38.0 °C(Predicted)
Density :1.297±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
pka :-0.03±0.20(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Safety Information
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Description
Jumonji AT-rich interactive domain 1 (JARID1) demethylases mediate the removal of methyl groups from trimethylated lysine 4 on histone 3 (H3K4me3). PBIT is a reversible, cell-permeable inhibitor of JARID1 family demethylases (IC50s = 6, 3, 4.9, and 28 μM for JARID1A, JARID1B, JARID1C, and JARID1D, respectively). It does not significantly affect the activity of UTX and JMJD3 demethylases. It increases trimethylation of H3K4 in HeLa cells and blocks the proliferation of tumor cells expressing high levels of JARID1B.More related product prices
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