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ChemicalBook >> CAS DataBase List >> (+/-)-THREO-9,10-DIHYDROXY-12(Z)-OCTADECENOIC ACID

(+/-)-THREO-9,10-DIHYDROXY-12(Z)-OCTADECENOIC ACID

(+/-)-THREO-9,10-DIHYDROXY-12(Z)-OCTADECENOIC ACID price.
  • $32 - $495
  • Product name: (+/-)-THREO-9,10-DIHYDROXY-12(Z)-OCTADECENOIC ACID
  • CAS: 263399-34-4
  • MF: C18H34O4
  • MW: 314.46
  • EINECS:
  • MDL Number:MFCD03412017
  • Synonyms:(+/-)-THREO-9,10-DIHYDROXY-12(Z)-OCTADECENOIC ACID;LEUKOTOXIN DIOL;(+/-)9,10-DIHOME;(+/-)9(10)-DIHYDROXY-12Z-OCTADECENOIC ACID;Threo-9,10-dihidroxy-12(z)-octadecenoic acid;12-Octadecenoic acid, 9,10-dihydroxy-, (12Z)-;(+/-)-THREO-9,10-DIHYDROXY-12(Z)-OCTADECENOIC ACID
Price5 Properties Safety Information Description
5 prices
Selected condition：
Brand
  • Cayman Chemical
  • TRC
Package
  • 25μg
  • 50μg
  • 100μg
  • 500μg
  • ManufacturerCayman Chemical
  • Product number53400
  • Product description(±)9(10)-DiHOME ≥98%
  • Packaging25μg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number53400
  • Product description(±)9(10)-DiHOME ≥98%
  • Packaging50μg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number53400
  • Product description(±)9(10)-DiHOME ≥98%
  • Packaging100μg
  • Price$111
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number53400
  • Product description(±)9(10)-DiHOME ≥98%
  • Packaging500μg
  • Price$486
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberD446388
  • Product description(+/-)9,10-DiHOME
  • Packaging100μg
  • Price$495
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 53400 (±)9(10)-DiHOME ≥98% 25μg $32 2024-03-01 Buy
Cayman Chemical 53400 (±)9(10)-DiHOME ≥98% 50μg $61 2024-03-01 Buy
Cayman Chemical 53400 (±)9(10)-DiHOME ≥98% 100μg $111 2024-03-01 Buy
Cayman Chemical 53400 (±)9(10)-DiHOME ≥98% 500μg $486 2024-03-01 Buy
TRC D446388 (+/-)9,10-DiHOME 100μg $495 2021-12-16 Buy

Properties

Boiling point :491.8±35.0 °C(Predicted)
Density :1.015±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 10 μg/ml
pka :4.78±0.10(Predicted)
form :Liquid
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Leukotoxin is the 9(10) epoxide of linoleic acid, generated by neutrophils during the oxidative burst. This unstable compound is rapidly degraded by epoxide hydrolases to form the diol, (±)9(10)-DiHOME. Mitochondrial dysfunction, vasodilation, and apoptosis are features of leukotoxin toxicity. In renal proximal tubular cells, the diol hydrolysis products of leukotoxin, such as (±)9(10)-DiHOME, have been directly implicated as the cytotoxic agent responsible for cell death.

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