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ChemicalBook >> CAS DataBase List >> 8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID

8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID

8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID price.
  • $121 - $1485
  • Product name: 8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID
  • CAS: 28872-28-8
  • MF: C18H30O2
  • MW: 278.43
  • EINECS:
  • MDL Number:MFCD05864027
  • Synonyms:JACARIC ACID;8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID;(8E,10Z,12Z)-Octadeca-8,10,12-trienoic acid;8,10,12-Octadecatrienoic acid, (8Z,10E,12Z)-
5 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000713
  • Product description8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID 95.00%
  • Packaging25MG
  • Price$1110.88
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16036
  • Product descriptionJacaric Acid ≥95%
  • Packaging1mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16036
  • Product descriptionJacaric Acid ≥95%
  • Packaging5mg
  • Price$543
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16036
  • Product descriptionJacaric Acid ≥95%
  • Packaging10mg
  • Price$961
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberJ210380
  • Product descriptionJacaricAcid
  • Packaging25mg
  • Price$1485
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation LIP0000713 8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID 95.00% 25MG $1110.88 2021-12-16 Buy
Cayman Chemical 16036 Jacaric Acid ≥95% 1mg $121 2024-03-01 Buy
Cayman Chemical 16036 Jacaric Acid ≥95% 5mg $543 2024-03-01 Buy
Cayman Chemical 16036 Jacaric Acid ≥95% 10mg $961 2024-03-01 Buy
TRC J210380 JacaricAcid 25mg $1485 2021-12-16 Buy

Properties

Boiling point :423.4±24.0 °C(Predicted)
Density :0.924±0.06 g/cm3(Predicted)
storage temp. :-20°C, Light sensitive
solubility :Ethanol (Soluble)
pka :4.77±0.10(Predicted)
form :Colourless Solution
Stability :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Jacaric acid is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants. Structurally, it is an 18-carbon ω-6 triene isomer of γ-linolenic acid . Jacaric acid induces cell cycle arrest and apoptosis in a variety of cancer cell lines (GI50 = 1-5 μM). It increases the production of reactive oxygen species, and cytotoxicity is abolished by the antioxidant α-tocopherol, suggesting that apoptosis results from oxidative stress. Jacaric acid is metabolized in vivo to conjugated linoleic acid , which is also cytotoxic to cancer cells. Jacaric acid inhibits cyclooxygenase-1 in vitro (Ki = 1.7 μM) and, with long term feeding, decreases stearoyl-CoA desaturase expression and activity in mice.