HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS
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- $72 - $3090
- Product name: HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS
- CAS: 29400-42-8
- MF: C33H44O8
- MW: 568.7
- EINECS:
- MDL Number:MFCD32689348
- Synonyms:17(20),24-trien-21-oicacid,6,16-bis(acetyloxy)-3,7-dioxo-29-nordammara-(4 ;6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-beta)--alph ;fumigacin ;HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS;(4α,8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid;(8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid;(8α,9β,13α,14β,17Z)-6β,16β-Diacetoxy-3,7-dioxo-29-nor-5α-dammara-1,17(20),24-trien-21-oic acid;29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4α,6β,8α,9β,13α,14β,16β,17Z)-
6 prices
Selected condition：
Brand
- Adipogen Life Sciences
- Apolloscientific
- Cayman Chemical
- TRC
Package
- 1mg
- 5mg
- 50mg
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0435-M005
- Product descriptionHelvolicacid ≥96%(HPLC,NMR)
- Packaging5mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIBR1050
- Product descriptionHelvolicacid
- Packaging1mg
- Price$109
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIBR1050
- Product descriptionHelvolicacid
- Packaging5mg
- Price$435
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21580
- Product descriptionHelvolic Acid ≥98%
- Packaging1mg
- Price$72
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21580
- Product descriptionHelvolic Acid ≥98%
- Packaging5mg
- Price$231
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberH235125
- Product descriptionHelvolicAcid
- Packaging50mg
- Price$3090
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | BVT-0435-M005 | Helvolicacid ≥96%(HPLC,NMR) | 5mg | $190 | 2021-12-16 | Buy |
| Apolloscientific | BIBR1050 | Helvolicacid | 1mg | $109 | 2021-12-16 | Buy |
| Apolloscientific | BIBR1050 | Helvolicacid | 5mg | $435 | 2021-12-16 | Buy |
| Cayman Chemical | 21580 | Helvolic Acid ≥98% | 1mg | $72 | 2024-03-01 | Buy |
| Cayman Chemical | 21580 | Helvolic Acid ≥98% | 5mg | $231 | 2024-03-01 | Buy |
| TRC | H235125 | HelvolicAcid | 50mg | $3090 | 2021-12-16 | Buy |
Properties
Melting point :215°
alpha :D25 -121° (chloroform)
Boiling point :552.56°C (rough estimate)
Density :1.1062 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :2-8°C
solubility :DMF:30.0(Max Conc. mg/mL);52.75(Max Conc. mM)
DMSO:20.0(Max Conc. mg/mL);35.17(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);35.17(Max Conc. mM) form :A crystalline solid
pka :4.05±0.41(Predicted)
color :White to off-white
alpha :D25 -121° (chloroform)
Boiling point :552.56°C (rough estimate)
Density :1.1062 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :2-8°C
solubility :DMF:30.0(Max Conc. mg/mL);52.75(Max Conc. mM)
DMSO:20.0(Max Conc. mg/mL);35.17(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);35.17(Max Conc. mM) form :A crystalline solid
pka :4.05±0.41(Predicted)
color :White to off-white
Safety Information
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Description
Helvolic acid is a mycotoxin originally isolated from A. fumigatus that has broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria. At 4-16 mg/L, it acted synergistically with erythromycin (500-2,000 mg/L) in vitro on five multi-drug resistant strains of S. aureus. At 10 mg/kg/d, it reduced tumor growth and prolonged survival synergistically with cyclophosphamide (20 mg/kg/d) in a mouse model of sarcoma but had no effect when administered alone.More related product prices
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