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ChemicalBook >> CAS DataBase List >> 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α

17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α

17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α price.
  • $70 - $545
  • Product name: 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
  • CAS: 294856-01-2
  • MF: C24H33F3O5
  • MW: 458.51
  • EINECS:
  • MDL Number:MFCD05863955
  • Synonyms:17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α;GGAGMUSEFHEEBF-XPRPYWGDSA-N;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pentyl]cyclopentyl]-, (5Z)-;17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
4 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number1546AH
  • Product description9alpha,11alpha,15R-Trihydroxy-17-(3-(trifluoromethyl)Phenyl)-18,19,20-trinor-prosta-5Z-en-1-oicacid
  • Packaging5mg
  • Price$440
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16895
  • Product description17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α ≥98%
  • Packaging1mg
  • Price$70
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16895
  • Product description17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α ≥98%
  • Packaging5mg
  • Price$308
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16895
  • Product description17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α ≥98%
  • Packaging10mg
  • Price$545
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1546AH 9alpha,11alpha,15R-Trihydroxy-17-(3-(trifluoromethyl)Phenyl)-18,19,20-trinor-prosta-5Z-en-1-oicacid 5mg $440 2021-12-16 Buy
Cayman Chemical 16895 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α ≥98% 1mg $70 2024-03-01 Buy
Cayman Chemical 16895 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α ≥98% 5mg $308 2024-03-01 Buy
Cayman Chemical 16895 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α ≥98% 10mg $545 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects. 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2α would act very much like the free acid of latanoprost.