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ChemicalBook >> CAS DataBase List >> 2-[3-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-propylsulfanyl]-benzoic acid

2-[3-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-propylsulfanyl]-benzoic acid

2-[3-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-propylsulfanyl]-benzoic acid price.
  • $36 - $1320
  • Product name: 2-[3-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-propylsulfanyl]-benzoic acid
  • CAS: 325850-81-5
  • MF: C22H17NO4S
  • MW: 391.44
  • EINECS:803-533-4
  • MDL Number:
  • Synonyms:2-((3-(1,3-Dioxo-(1H)benzo[de]isoquinolin-2(3H)-yl)propyl)thio)benzoic Acid;2-[[3-(1,3-Dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]-benzoic acid;GRI977143;2-[3-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-propylsulfanyl]-benzoic acid;GRI977143; GRI-977143;Benzoic acid, 2-[[3-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]-;2-((3-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)propyl)thio)benzoic acid , GRI977143
Price14 Properties Safety Information Description
14 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 50
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product numberSYN5176
  • Product descriptionGRI-977143
  • Packaging10mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0026411
  • Product description2-((3-(1,3-DIOXO-(1H)BENZO[DE]ISOQUINOLIN-2(3H)-YL)PROPYL)THIO)BENZOIC ACID 95.00%
  • Packaging5MG
  • Price$501.69
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4471
  • Product descriptionGRI977143
  • Packaging10mg
  • Price$314
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4471
  • Product descriptionGRI977143
  • Packaging50mg
  • Price$1290
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21900
  • Product descriptionGRI-977143 ≥98%
  • Packaging1mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21900
  • Product descriptionGRI-977143 ≥98%
  • Packaging5mg
  • Price$95
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21900
  • Product descriptionGRI-977143 ≥98%
  • Packaging10mg
  • Price$172
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21900
  • Product descriptionGRI-977143 ≥98%
  • Packaging25mg
  • Price$384
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0544
  • Product descriptionGRI977143 ≥98% (HPLC)
  • Packaging5mg
  • Price$128
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0544
  • Product descriptionGRI977143 ≥98% (HPLC)
  • Packaging25mg
  • Price$484
  • Updated2023-01-07
  • Buy
  • ManufacturerTocris
  • Product number4779
  • Product descriptionGRI977143 ≥98%(HPLC)
  • Packaging10
  • Price$212
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4779
  • Product descriptionGRI977143 ≥98%(HPLC)
  • Packaging50
  • Price$870
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberD486350
  • Product description2-((3-(1,3-Dioxo-(1H)benzo[de]isoquinolin-2(3H)-yl)propyl)thio)benzoicAcid
  • Packaging100mg
  • Price$1320
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255399
  • Product descriptionGRI 977143
  • Packaging10mg
  • Price$466
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5176 GRI-977143 10mg $145 2021-12-16 Buy
American Custom Chemicals Corporation API0026411 2-((3-(1,3-DIOXO-(1H)BENZO[DE]ISOQUINOLIN-2(3H)-YL)PROPYL)THIO)BENZOIC ACID 95.00% 5MG $501.69 2021-12-16 Buy
ApexBio Technology A4471 GRI977143 10mg $314 2021-12-16 Buy
ApexBio Technology A4471 GRI977143 50mg $1290 2021-12-16 Buy
Cayman Chemical 21900 GRI-977143 ≥98% 1mg $36 2024-03-01 Buy
Cayman Chemical 21900 GRI-977143 ≥98% 5mg $95 2024-03-01 Buy
Cayman Chemical 21900 GRI-977143 ≥98% 10mg $172 2024-03-01 Buy
Cayman Chemical 21900 GRI-977143 ≥98% 25mg $384 2024-03-01 Buy
Sigma-Aldrich SML0544 GRI977143 ≥98% (HPLC) 5mg $128 2024-03-01 Buy
Sigma-Aldrich SML0544 GRI977143 ≥98% (HPLC) 25mg $484 2023-01-07 Buy
Tocris 4779 GRI977143 ≥98%(HPLC) 10 $212 2021-12-16 Buy
Tocris 4779 GRI977143 ≥98%(HPLC) 50 $870 2021-12-16 Buy
TRC D486350 2-((3-(1,3-Dioxo-(1H)benzo[de]isoquinolin-2(3H)-yl)propyl)thio)benzoicAcid 100mg $1320 2021-12-16 Buy
Usbiological 255399 GRI 977143 10mg $466 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
color :white to light brown

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

GRI-977143 is an agonist of G protein-coupled lysophosphatidic acid receptor 2 (LPA2) with an EC50 value of 3.3 μM in LPA2-transfected RH7777 cells. It is selective for LPA2, having no activity at LPA1, LPA3, LPA4, and LPA5 at concentrations up to 10 μM. GRI-977143 increases growth and reduces caspase-3 and -7 activation in LPA2-transduced MEF fibroblasts. It increases MM1 rat hepatoma cell invasion and inhibits apoptosis of IEC-6 cells induced by TNF-α, doxorubicin , or serum withdrawal. GRI-977143 also rescues apoptotic cells from γ-irradiation-induced injury in vitro and in vivo.

Suppliers and manufacturers

TargetMol Chemicals Inc.
GRI977143
$33.00 /1mg
GRI977143 CAS:325850-81-5
Aladdin Scientific
Amadis Chemical Company Limited J & K SCIENTIFIC LTD. Shanghai Yolne Chemical Co., Ltd. AdooQ BioScience, LLC EMMX Biotechnology LLC Pharmacodia (Beijing) Co.,Ltd Shanghai EFE Biological Technology Co., Ltd. Tianjin Kailiqi Biotechnology Co., Ltd.