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ChemicalBook >> CAS DataBase List >> 5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-

5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-

5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]- price.
  • $80 - $347
  • Product name: 5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-
  • CAS: 330785-84-7
  • MF: C18H21ClN4O4
  • MW: 392.84
  • EINECS:807-887-0
  • MDL Number:MFCD18072441
  • Synonyms:5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-;(S)-4-(3-chloro-4-MethoxybenzylaMino)-5-carboxy-2-(2-hydroxyMethyl-1-pyrrolidinyl)pyriMidine;4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-5-pyrimidinecarboxylic acid;(S)-4-((3-Chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)pyriMidine-5-carboxylic acid;(S)-4-(3-Chloro-4-methoxybenzylamino)-5-carboxy-2-(2-hydroxy...;5-PYRIMIDINECARBOXYLIC ACID, 4-[[(3-CHLORO-4-METHOXYPHENYL)METHYL]AMINO]-2-[(2S)-2-(HYDROXYMETHYL)-;4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylic acid;(S)-4-(3-Chloro-4-Methoxybenzyl)Amino)-2-(2-(Hydroxymethyl)Pyrolidin-1-Yl)Pyrimidine-5-Carboxylic Acid
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • Chemenu
  • Crysdot
  • TRC
Package
  • 250mg
  • 1g
  • 5g
  • ManufacturerChemenu
  • Product numberCM167400
  • Product description(S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylicacid 98%
  • Packaging1g
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM167400
  • Product description(S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylicacid 98%
  • Packaging5g
  • Price$327
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11143931
  • Product description(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylicacid 98%
  • Packaging5g
  • Price$347
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC371450
  • Product description(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylicAcid
  • Packaging250mg
  • Price$80
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Chemenu CM167400 (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylicacid 98% 1g $128 2021-12-16 Buy
Chemenu CM167400 (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylicacid 98% 5g $327 2021-12-16 Buy
Crysdot CD11143931 (S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylicacid 98% 5g $347 2021-12-16 Buy
TRC C371450 (S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylicAcid 250mg $80 2021-12-16 Buy

Properties

Melting point :>176oC (dec.)
Boiling point :647.6±65.0 °C(Predicted)
Density :1.415±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :1.80±0.36(Predicted)
color :White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic Acid is used in the preparation of an Avanafil (A794670) intermediate. Avanafil is a phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.

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Suppliers and manufacturers

Shanghai Yingrui Biopharma Co., Ltd.
4-(3-chloro-4-methoxybenzylamino) -2-((S)-2-(hydroxymethyl) pyrrolidin-1-yl)pyrimidine-5- carboxylic acid
$0.00 /0KG
4-(3-chloro-4-methoxybenzylamino) -2-((S)-2-(hydroxymethyl) pyrrolidin-1-yl)pyrimidine-5- carboxylic acid CAS:330785-84-7
career henan chemical co
5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-
$100.00 /1KG
5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]- CAS:330785-84-7
Shanghai Daken Advanced Materials Co.,Ltd
Beijing Cooperate Pharmaceutical Co.,Ltd
Nanjing Finetech Chemical Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
NINGBO INNO PHARMCHEM CO., LTD.
Jinan Finer Chemical Co., Ltd
Hubei xin bonus chemical co. LTD
Chongqing Chemdad Co., Ltd