PROSTAGLANDINS F2ALPHA METHYL ESTER
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- $32 - $505.05
- Product name: PROSTAGLANDINS F2ALPHA METHYL ESTER
- CAS: 33854-16-9
- MF: C21H36O5
- MW: 368.51
- EINECS:201-185-2
- MDL Number:MFCD00133790
- Synonyms:(5Z,9S,11S,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid methyl ester;9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, METHYL ESTER;PGF2ALPHA-OME;PROSTAGLANDINS F2ALPHA METHYL ESTER;PROSTAGLANDIN F2ALPHA METHYL ESTER;(5Z,13E,15S)-9α,11α,15-Trihydroxyprosta-5,13-dien-1-oic acid methyl ester;(Z)-Methyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)hept-5-enoate;13e,15s)-alph
7 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- Sigma-Aldrich
Package
- 500μg
- 1mg
- 5mg
- 10mg
- ManufacturerAK Scientific
- Product number2010AH
- Product descriptionProstaglandinF2alphamethylester
- Packaging5mg
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0001599
- Product descriptionPROSTAGLANDIN-F2ALPHA-METHYL ESTER 95.00%
- Packaging5MG
- Price$505.05
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16011
- Product descriptionProstaglandin F2α methyl ester ≥98%
- Packaging500μg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16011
- Product descriptionProstaglandin F2α methyl ester ≥98%
- Packaging1mg
- Price$61
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16011
- Product descriptionProstaglandin F2α methyl ester ≥98%
- Packaging5mg
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16011
- Product descriptionProstaglandin F2α methyl ester ≥98%
- Packaging10mg
- Price$426
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberP0314
- Product descriptionProstaglandin F2α methyl ester ~5 mg/mL in methyl acetate, ≥95% (HPLC)
- Packaging1mg
- Price$315
- Updated2022-05-15
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2010AH | ProstaglandinF2alphamethylester | 5mg | $370 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0001599 | PROSTAGLANDIN-F2ALPHA-METHYL ESTER 95.00% | 5MG | $505.05 | 2021-12-16 | Buy |
| Cayman Chemical | 16011 | Prostaglandin F2α methyl ester ≥98% | 500μg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 16011 | Prostaglandin F2α methyl ester ≥98% | 1mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 16011 | Prostaglandin F2α methyl ester ≥98% | 5mg | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 16011 | Prostaglandin F2α methyl ester ≥98% | 10mg | $426 | 2024-03-01 | Buy |
| Sigma-Aldrich | P0314 | Prostaglandin F2α methyl ester ~5 mg/mL in methyl acetate, ≥95% (HPLC) | 1mg | $315 | 2022-05-15 | Buy |
Properties
Boiling point :418.83°C (rough estimate)
Density :1.0390 (rough estimate)
refractive index :1.6120 (estimate)
Flash point :-9 °C
storage temp. :−20°C
solubility :DMF: 35 mg/ml; DMSO: 35 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 0.4 mg/ml
Density :1.0390 (rough estimate)
refractive index :1.6120 (estimate)
Flash point :-9 °C
storage temp. :−20°C
solubility :DMF: 35 mg/ml; DMSO: 35 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 0.4 mg/ml
Safety Information
| Symbol(GHS): |
 
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Description
Prostaglandin F2α methyl ester (PGF2α methyl ester) is an analog of PGF2α in which the C-1 carboxyl group has been esterified as the methyl ester. PGF2α methyl ester was one of the first PG esters shown to have ocular hypotensive activity. This compound continues to be a standard by which other ocular hypotensive PG prodrugs are evaluated. The methyl ester is about 4-5 times more potent than the free acid, PGF2α. This difference is attributed to improved corneal penetration, and a depot effect of prolonged retention of the ester form of the compound in ocular tissue. A 2.5 μg dose of PGF2α-OMe applied to the eyes of cats results in a 6-8 mm Hg reduction in IOP.Related product price
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