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ChemicalBook >> CAS DataBase List >> 1-(4-CHLOROPHENYL)-4-(TRIFLUOROMETHYL)[1,2,4]TRIAZOLO[4,3-A]QUINOXALINE

1-(4-CHLOROPHENYL)-4-(TRIFLUOROMETHYL)[1,2,4]TRIAZOLO[4,3-A]QUINOXALINE

1-(4-CHLOROPHENYL)-4-(TRIFLUOROMETHYL)[1,2,4]TRIAZOLO[4,3-A]QUINOXALINE price.
Price9 Properties Safety Information Description
9 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
Package
  • 1MG
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number8160CE
  • Product description1-(4-Chlorophenyl)-4-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline
  • Packaging5mg
  • Price$286
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8160CE
  • Product description1-(4-Chlorophenyl)-4-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline
  • Packaging10mg
  • Price$452
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0086572
  • Product description1-(4-CHLOROPHENYL)-4-(TRIFLUOROMETHYL)[1,2,4]TRIAZOLO[4,3-A]QUINOXALINE 95.00%
  • Packaging1MG
  • Price$647.61
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0086572
  • Product description1-(4-CHLOROPHENYL)-4-(TRIFLUOROMETHYL)[1,2,4]TRIAZOLO[4,3-A]QUINOXALINE 95.00%
  • Packaging10MG
  • Price$679.14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0086572
  • Product description1-(4-CHLOROPHENYL)-4-(TRIFLUOROMETHYL)[1,2,4]TRIAZOLO[4,3-A]QUINOXALINE 95.00%
  • Packaging5MG
  • Price$687.35
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22479
  • Product descriptionR-8507 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22479
  • Product descriptionR-8507 ≥98%
  • Packaging5mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22479
  • Product descriptionR-8507 ≥98%
  • Packaging10mg
  • Price$319
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22479
  • Product descriptionR-8507 ≥98%
  • Packaging25mg
  • Price$704
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8160CE 1-(4-Chlorophenyl)-4-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline 5mg $286 2021-12-16 Buy
AK Scientific 8160CE 1-(4-Chlorophenyl)-4-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline 10mg $452 2021-12-16 Buy
American Custom Chemicals Corporation HCH0086572 1-(4-CHLOROPHENYL)-4-(TRIFLUOROMETHYL)[1,2,4]TRIAZOLO[4,3-A]QUINOXALINE 95.00% 1MG $647.61 2021-12-16 Buy
American Custom Chemicals Corporation HCH0086572 1-(4-CHLOROPHENYL)-4-(TRIFLUOROMETHYL)[1,2,4]TRIAZOLO[4,3-A]QUINOXALINE 95.00% 10MG $679.14 2021-12-16 Buy
American Custom Chemicals Corporation HCH0086572 1-(4-CHLOROPHENYL)-4-(TRIFLUOROMETHYL)[1,2,4]TRIAZOLO[4,3-A]QUINOXALINE 95.00% 5MG $687.35 2021-12-16 Buy
Cayman Chemical 22479 R-8507 ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 22479 R-8507 ≥98% 5mg $169 2024-03-01 Buy
Cayman Chemical 22479 R-8507 ≥98% 10mg $319 2024-03-01 Buy
Cayman Chemical 22479 R-8507 ≥98% 25mg $704 2024-03-01 Buy

Properties

Density :1.55±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 16 mg/ml; DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml; DMSO: 2 mg/ml
form :A crystalline solid
pka :-2.21±0.40(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

R-8507 is a small molecule antagonist of the TNF-α type 1 receptor (TNF-αRI).1 It inhibits the expression of intercellular adhesion molecule-1 (ICAM-1) induced by TNF-α and IL-1β with EC50 values of 2.45 and 3.79 μM, respectively, in an ELISA using A549 lung epithelial cells.{|Gururaja2007|} It also disrupts the interaction of the TNF-αRI with receptor interacting protein 1 (RIP1) and TNF-αR-associated death domain protein (TRADD), preventing internalization of the receptor complex.

Suppliers and manufacturers

Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. Shanghai Yifei Biotechnology Co. , Ltd. TargetMol Chemicals Inc.