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ChemicalBook >> CAS DataBase List >> (5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone

(5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone

(5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone price.
Price8 Properties Safety Information Description
8 prices
Selected condition：
Brand
  • ApexBio Technology
  • Cayman Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 1
  • 500μg
  • 1mg
  • 2.5mg
  • 5mg
  • 10mg
  • ManufacturerApexBio Technology
  • Product numberB7580
  • Product descriptionTCS2510
  • Packaging5mg
  • Price$854
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13281
  • Product descriptionCAY10598 ≥98%
  • Packaging500μg
  • Price$96
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13281
  • Product descriptionCAY10598 ≥98%
  • Packaging1mg
  • Price$134
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13281
  • Product descriptionCAY10598 ≥98%
  • Packaging5mg
  • Price$526
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13281
  • Product descriptionCAY10598 ≥98%
  • Packaging10mg
  • Price$954
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number4069
  • Product descriptionTCS2510 ≥98%(HPLC)
  • Packaging1
  • Price$229
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberT012630
  • Product descriptionTCS2510
  • Packaging2.5mg
  • Price$295
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256878
  • Product descriptionTCS 2510
  • Packaging1mg
  • Price$489
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B7580 TCS2510 5mg $854 2021-12-16 Buy
Cayman Chemical 13281 CAY10598 ≥98% 500μg $96 2024-03-01 Buy
Cayman Chemical 13281 CAY10598 ≥98% 1mg $134 2024-03-01 Buy
Cayman Chemical 13281 CAY10598 ≥98% 5mg $526 2024-03-01 Buy
Cayman Chemical 13281 CAY10598 ≥98% 10mg $954 2024-03-01 Buy
Tocris 4069 TCS2510 ≥98%(HPLC) 1 $229 2021-12-16 Buy
TRC T012630 TCS2510 2.5mg $295 2021-12-16 Buy
Usbiological 256878 TCS 2510 1mg $489 2021-12-16 Buy

Properties

Boiling point :632.0±65.0 °C(Predicted)
Density :1.238±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)
form :Powder
pka :5.07±0.10(Predicted)
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10598 is a very potent agonist of EP4, binding with a Ki value of 1.2 nM. Moreover, it does not bind EP1, EP2, EP3, or other prostanoid receptors, including DP, FP, IP, and TP. First generation EP4 receptor-selective agonists have been shown to reduce inflammation, improve bone healing, provide cardio- and neuroprotection, and reduce renal dysfunction, suggesting some clinical applications for EP4 agonists.

Suppliers and manufacturers

TargetMol Chemicals Inc.
Aladdin Scientific 3B Pharmachem (Wuhan) International Co.,Ltd. EMMX Biotechnology LLC BOC Sciences ChemeGen(Shanghai) Biotechnology Co.,Ltd. Energy Chemical Shanghai Universal Biotech Co.,Ltd amyjetsci TargetMol Chemicals Inc.