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ChemicalBook >> CAS DataBase List >> 2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE

2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE

2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE price.
  • $28 - $609
  • Product name: 2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE
  • CAS: 349085-38-7
  • MF: C18H21N5O3
  • MW: 355.39
  • EINECS:
  • MDL Number:MFCD02007349
  • Synonyms:2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE;HC 030031;2-(1,3-dimethyl-2,6-dioxo-2,3-dihydro-1H-purin-7(6H)-yl)-N-(4-isopropylphenyl)acetamide;1,2,3,6-Tetrahydro-1,3-diMethyl-N-[4-(1-Methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetaMide;7H-Purine-7-acetamide, 1,2,3,6-tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-;HC-030031;HC 030031;HC030031;2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-(4-propan-2-ylphenyl)acetamide;HC 030031 1G
21 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 10mg
  • 50
  • 5mg
  • 50mg
  • 10
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number2459AH
  • Product description2-(1,3-Dimethyl-2,6-dioxopurin-7-yl)-N-(4-propan-2-ylphenyl)acetamide
  • Packaging10mg
  • Price$137
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2100
  • Product descriptionHC-030031
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545811
  • Product descriptionHC-030031 >98%
  • Packaging10mg
  • Price$154.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545811
  • Product descriptionHC-030031 >98%
  • Packaging50mg
  • Price$299.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH23741
  • Product descriptionHC 030031
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH23741
  • Product descriptionHC 030031
  • Packaging50mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11923
  • Product descriptionHC-030031 ≥98%
  • Packaging5mg
  • Price$28
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11923
  • Product descriptionHC-030031 ≥98%
  • Packaging10mg
  • Price$48
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11923
  • Product descriptionHC-030031 ≥98%
  • Packaging50mg
  • Price$140
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1040
  • Product descriptionHC-030031 95.91%
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1040
  • Product descriptionHC-030031 95.91%
  • Packaging50mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1040
  • Product descriptionHC-030031 95.91%
  • Packaging100mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002152
  • Product descriptionHC-030031 98+%
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31002152
  • Product descriptionHC-030031 98+%
  • Packaging50mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002152
  • Product descriptionHC-030031 98+%
  • Packaging100mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC5200
  • Product descriptionHC-030031 >98%
  • Packaging100mg
  • Price$250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2459AH 2-(1,3-Dimethyl-2,6-dioxopurin-7-yl)-N-(4-propan-2-ylphenyl)acetamide 10mg $137 2021-12-16 Buy
ApexBio Technology B2100 HC-030031 10mg $45 2021-12-16 Buy
Biorbyt Ltd orb545811 HC-030031 >98% 10mg $154.7 2021-12-16 Buy
Biorbyt Ltd orb545811 HC-030031 >98% 50mg $299.2 2021-12-16 Buy
Biosynth Carbosynth FH23741 HC 030031 10mg $65 2021-12-16 Buy
Biosynth Carbosynth FH23741 HC 030031 50mg $228 2021-12-16 Buy
Cayman Chemical 11923 HC-030031 ≥98% 5mg $28 2024-03-01 Buy
Cayman Chemical 11923 HC-030031 ≥98% 10mg $48 2024-03-01 Buy
Cayman Chemical 11923 HC-030031 ≥98% 50mg $140 2024-03-01 Buy
ChemScene CS-1040 HC-030031 95.91% 10mg $50 2021-12-16 Buy
ChemScene CS-1040 HC-030031 95.91% 50mg $120 2021-12-16 Buy
ChemScene CS-1040 HC-030031 95.91% 100mg $180 2021-12-16 Buy
Crysdot CD31002152 HC-030031 98+% 10mg $55 2021-12-16 Buy
Crysdot CD31002152 HC-030031 98+% 50mg $158 2021-12-16 Buy
Crysdot CD31002152 HC-030031 98+% 100mg $198 2021-12-16 Buy
DC Chemicals DC5200 HC-030031 >98% 100mg $250 2021-12-16 Buy

Properties

Melting point :221-223°C
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble10mg/mL, clear
pka :13.71±0.70(Predicted)
form :White solid
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :HEQDZPHDVAOBLN-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Transient receptor potential cation channel A1 (TRPA1) is an ankyrin-like ion channel which acts as a sensor for chemical irritants, pain, and cold. It is activated by allyl isothiocyanate (AITC), formalin, hydrogen peroxide, tear gas, and other compounds. HC-030031 is a selective TRPA1 blocker, antagonizing TRPA1-mediated calcium influx induced by AITC and formalin (IC50 = 6.2 and 5.3 μM, respectively). It does not block currents mediated by TRPV1, TRPV3, TRPV4 hERG, or NaV1.2 channels. HC-030031 can be used in cells or delivered to animals orally, by inhalation, or by injection. Oral administration (100 mg/kg) of HC-030031 significantly reversed mechanical hypersensitivity in rat models of chronic inflammatory or neuropathic pain, while local injection (100 μg) into inflamed mouse hind paws attenuated mechanical, but not heat, hypersensitivity.

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