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ChemicalBook >> CAS DataBase List >> 4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide

4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide

4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide price.
  • $34 - $750
  • Product name: 4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide
  • CAS: 36707-00-3
  • MF: C13H15N5O6
  • MW: 337.29
  • EINECS:
  • MDL Number:
  • Synonyms:NSC 177223;4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide;4-Amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide;API-1;API-1(NSC 177223);Pyrido[2,3-d]pyrimidine-6-carboxamide, 4-amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-;4-Amino-5-oxo-8-pentofuranosyl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide;4-amino-8-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxamide
11 prices
Selected condition:
Brand
  • Cayman Chemical
  • CSNpharm
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerCayman Chemical
  • Product number22081
  • Product descriptionAPI-1 ≥98%
  • Packaging1mg
  • Price$34
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22081
  • Product descriptionAPI-1 ≥98%
  • Packaging5mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22081
  • Product descriptionAPI-1 ≥98%
  • Packaging10mg
  • Price$270
  • Updated2024-03-01
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN22684
  • Product descriptionAPI-1
  • Packaging10mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN22684
  • Product descriptionAPI-1
  • Packaging25mg
  • Price$442
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number52584
  • Product descriptionNSC177223
  • Packaging10mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1342
  • Product descriptionAPI-1
  • Packaging5mg
  • Price$160
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1342
  • Product descriptionAPI-1
  • Packaging25mg
  • Price$552
  • Updated2022-05-15
  • Buy
  • ManufacturerTocris
  • Product number3897
  • Product descriptionAPI-1 ≥96%(HPLC)
  • Packaging10
  • Price$346
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberN900270
  • Product descriptionNSC177223
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number165663
  • Product descriptionNSC 177223
  • Packaging5mg
  • Price$460
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 22081 API-1 ≥98% 1mg $34 2024-03-01 Buy
Cayman Chemical 22081 API-1 ≥98% 5mg $152 2024-03-01 Buy
Cayman Chemical 22081 API-1 ≥98% 10mg $270 2024-03-01 Buy
CSNpharm CSN22684 API-1 10mg $260 2021-12-16 Buy
CSNpharm CSN22684 API-1 25mg $442 2021-12-16 Buy
Medical Isotopes, Inc. 52584 NSC177223 10mg $750 2021-12-16 Buy
Sigma-Aldrich SML1342 API-1 5mg $160 2024-03-01 Buy
Sigma-Aldrich SML1342 API-1 25mg $552 2022-05-15 Buy
Tocris 3897 API-1 ≥96%(HPLC) 10 $346 2021-12-16 Buy
TRC N900270 NSC177223 5mg $160 2021-12-16 Buy
Usbiological 165663 NSC 177223 5mg $460 2021-12-16 Buy

Properties

storage temp. :Store at RT
solubility :DMF: slightly soluble; DMSO: 2 mg/ml
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

NSC 177223 is a Akt/protein kinase B inhibitor. It binds to pleckstrin homologous domain of Akt and blocks Akt membrane translocation. Treatment of cancer cells with NSC 177223 results in inhibition of the kinase activities and induction of cell growth arrest and apoptosis selectively in human cancer cells that harbor constitutively activated Akt.