3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole
- $98 - $13415
- Product name: 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole
- CAS: 395104-30-0
- MF: C22H24N6O
- MW: 388.47
- EINECS:200-528-9
- MDL Number:MFCD16038646
- Synonyms:3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole;CC-401;CC-401 (HCl);3-(3-(2-(piperidin-1-yl)ethoxy)phenyl)-5-(1H-1,2,4-triazol-3-yl)-1H-indazole;CC4013-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole;CC-401, >=98%;3-(3-(2-(Piperidin-1-yl)ethoxy)phenyl)-5-(1H-1,2,4-triazol-5-yl)-1H-indazole;1-[5-(1H-1,2,4-Triazol-5-yl)-1H-indazol-3-yl]-3-(2-piperidinoethoxy)benzene
24 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- Crysdot
- Matrix Scientific
- TRC
Package
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- 5g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberY0278
- Product description3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1h-1,2,4-triazol-5-yl)-1H-indazole
- Packaging5g
- Price$13415
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000066
- Product descriptionCC-401 95.00%
- Packaging5MG
- Price$335.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1260
- Product descriptionCC-401
- Packaging5mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1260
- Product descriptionCC-401
- Packaging10mM(in 1mL DMSO)
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1260
- Product descriptionCC-401
- Packaging10mg
- Price$251
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1260
- Product descriptionCC-401
- Packaging50mg
- Price$744
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2025
- Product descriptionCC-401 99%
- Packaging5mg
- Price$126.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2025
- Product descriptionCC-401 99%
- Packaging25mg
- Price$511.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611609
- Product descriptionCC-401
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180953
- Product descriptionCC-401 >98%
- Packaging100mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611609
- Product descriptionCC-401
- Packaging250mg
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180953
- Product descriptionCC-401 >98%
- Packaging250mg
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611609
- Product descriptionCC-401
- Packaging1g
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180953
- Product descriptionCC-401 >98%
- Packaging1000mg
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18867
- Product descriptionCC-401 ≥98%
- Packaging1mg
- Price$106
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18867
- Product descriptionCC-401 ≥98%
- Packaging5mg
- Price$467
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | Y0278 | 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1h-1,2,4-triazol-5-yl)-1H-indazole | 5g | $13415 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000066 | CC-401 95.00% | 5MG | $335.5 | 2021-12-16 | Buy |
ApexBio Technology | B1260 | CC-401 | 5mg | $139 | 2021-12-16 | Buy |
ApexBio Technology | B1260 | CC-401 | 10mM(in 1mL DMSO) | $150 | 2021-12-16 | Buy |
ApexBio Technology | B1260 | CC-401 | 10mg | $251 | 2021-12-16 | Buy |
ApexBio Technology | B1260 | CC-401 | 50mg | $744 | 2021-12-16 | Buy |
Axon Medchem | Axon2025 | CC-401 99% | 5mg | $126.5 | 2021-12-16 | Buy |
Axon Medchem | Axon2025 | CC-401 99% | 25mg | $511.5 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611609 | CC-401 | 100mg | $690.2 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180953 | CC-401 >98% | 100mg | $765 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611609 | CC-401 | 250mg | $1356.6 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180953 | CC-401 >98% | 250mg | $1356.6 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611609 | CC-401 | 1g | $2691.1 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180953 | CC-401 >98% | 1000mg | $2691.1 | 2021-12-16 | Buy |
Cayman Chemical | 18867 | CC-401 ≥98% | 1mg | $106 | 2024-03-01 | Buy |
Cayman Chemical | 18867 | CC-401 ≥98% | 5mg | $467 | 2024-03-01 | Buy |
Properties
Boiling point :681.5±65.0 °C(Predicted)
Density :1.275
storage temp. :Store at -20°C
solubility :≥19.4 mg/mL in DMSO; ≥2.32 mg/mL in EtOH with ultrasonic; ≥8.7 mg/mL in H2O
form :solid
pka :9.44±0.20(Predicted)
Density :1.275
storage temp. :Store at -20°C
solubility :≥19.4 mg/mL in DMSO; ≥2.32 mg/mL in EtOH with ultrasonic; ≥8.7 mg/mL in H2O
form :solid
pka :9.44±0.20(Predicted)
Safety Information
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Description
c-Jun N-terminal kinases (JNKs) are MAP kinase family members that become highly activated after cells are exposed to stress conditions and are poorly activated by exposure to growth factors or mitogens. CC-401 is a potent inhibitor of all three JNK isoforms (Ki values range from 25 to 50 nM). It has at least 40-fold selectivity for JNK compared with other related kinases. CC-401 is bioavailable when delivered by gavage, blocking JNK signaling and renal fibrosis in a rat obstructed kidney model. It also has been shown to decrease hepatic necrosis and apoptosis after orthotopic liver transplantation and prevent acute renal failure following ischemia/reperfusion associated with renal transplantation in rats.More related product prices
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3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole CAS:395104-30-0
3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole CAS:395104-30-0