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ChemicalBook >> CAS DataBase List >> N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE

N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE

N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE price.
  • $57 - $412
  • Product name: N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE
  • CAS: 398138-28-8
  • MF: C22H37NO5
  • MW: 395.54
  • EINECS:
  • MDL Number:MFCD02259323
  • Synonyms:PGD2-EA;PROSTAGLANDIN D2 ETHANOLAMIDE;N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE;Prostaglandin D2 Ethanolamide Lipid Maps MS Standard;(Z)-N-(2-hydroxyethyl)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enamide;Prostaglandin D2 Ethanolamide MaxSpecStandard;Prosta-5,13-dien-1-amide, 9,15-dihydroxy-N-(2-hydroxyethyl)-11-oxo-, (5Z,9α,13E,15S)-
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • Cayman Chemical
Package
  • 100μg
  • 500μg
  • 1mg
  • 5mg
  • ManufacturerCayman Chemical
  • Product number12012
  • Product descriptionProstaglandin D2 Ethanolamide
  • Packaging500μg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number12012
  • Product descriptionProstaglandin D2 Ethanolamide ≥96%
  • Packaging1mg
  • Price$89
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007203
  • Product descriptionProstaglandin D2 Ethanolamide MaxSpec? Standard ≥95%
  • Packaging100μg
  • Price$115
  • Updated2023-01-06
  • Buy
  • ManufacturerCayman Chemical
  • Product number12012
  • Product descriptionProstaglandin D2 Ethanolamide ≥96%
  • Packaging5mg
  • Price$412
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 12012 Prostaglandin D2 Ethanolamide 500μg $57 2024-03-01 Buy
Cayman Chemical 12012 Prostaglandin D2 Ethanolamide ≥96% 1mg $89 2024-03-01 Buy
Cayman Chemical 10007203 Prostaglandin D2 Ethanolamide MaxSpec? Standard ≥95% 100μg $115 2023-01-06 Buy
Cayman Chemical 12012 Prostaglandin D2 Ethanolamide ≥96% 5mg $412 2024-03-01 Buy

Properties

Boiling point :630.7±55.0 °C(Predicted)
Density :1.134±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 8.3 mg/ml; DMSO: 8.3 mg/ml; Ethanol: 12.5 mg/ml; PBS (7.2): 2.5 mg/ml
pka :13.86±0.60(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase. PGD2-EA is inactive against recombinant prostanoid receptors, including the D prostanoid receptor. It increases the frequency of miniature inhibitory postsynaptic currents in primary cultured hippocampal neurons, an effect which is the opposite of that induced by anandamide.. PGD2-EA also induces apoptosis in colorectal carcinoma cell lines.

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