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ChemicalBook >> CAS DataBase List >> JNJ 5207852 dihydrochloride

JNJ 5207852 dihydrochloride

JNJ 5207852 dihydrochloride price.
  • $65 - $4469.3
  • Product name: JNJ 5207852 dihydrochloride
  • CAS: 398473-34-2
  • MF: C20H32N2O
  • MW: 316.48
  • EINECS:
  • MDL Number:MFCD05974930
  • Synonyms:JNJ 5207852 dihydrochloride;JNJ 5207852;Piperidine, 1-[3-[4-(1-piperidinylmethyl)phenoxy]propyl]-;1-[3-[4-(1-Piperidinylmethyl)phenoxy]propyl]piperidine hydrochloride;1-{3-[4-(PIPERIDIN-1-YLMETHYL)PHENOXY]PROPYL}PIPERIDINE;1-(4-(3-piperidin-1-ylpropoxy)benzyl)piperidine;sleep,low,JNJ5207852,Histamine Receptor,JNJ-5207852,JNJ 5207852,Inhibitor,REM,toxicity,inhibit
Price33 Properties Safety Information Description
33 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
Package
  • 10
  • 5mg
  • 1MG
  • 50
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number6433CH
  • Product description1-[4-(3-Piperidinopropoxy)benzyl]piperidine
  • Packaging5mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6433CH
  • Product description1-[4-(3-Piperidinopropoxy)benzyl]piperidine
  • Packaging10mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6433CH
  • Product description1-[4-(3-Piperidinopropoxy)benzyl]piperidine
  • Packaging25mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6433CH
  • Product description1-[4-(3-Piperidinopropoxy)benzyl]piperidine
  • Packaging50mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA774214
  • Product description1-(4-(3-(Piperidin-1-yl)propoxy)benzyl)piperidine 99+%
  • Packaging5mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA774214
  • Product description1-(4-(3-(Piperidin-1-yl)propoxy)benzyl)piperidine 99+%
  • Packaging10mg
  • Price$224
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA774214
  • Product description1-(4-(3-(Piperidin-1-yl)propoxy)benzyl)piperidine 99+%
  • Packaging25mg
  • Price$292
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA774214
  • Product description1-(4-(3-(Piperidin-1-yl)propoxy)benzyl)piperidine 99+%
  • Packaging50mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0073414
  • Product description1-[4-(3-PIPERIDIN-1-YLPROPOXY)BENZYL]PIPERIDINE 95.00%
  • Packaging1MG
  • Price$452
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0073414
  • Product description1-[4-(3-PIPERIDIN-1-YLPROPOXY)BENZYL]PIPERIDINE 95.00%
  • Packaging5MG
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0073414
  • Product description1-[4-(3-PIPERIDIN-1-YLPROPOXY)BENZYL]PIPERIDINE 95.00%
  • Packaging10MG
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5513
  • Product descriptionJNJ5207852dihydrochloride
  • Packaging5mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5513
  • Product descriptionJNJ5207852dihydrochloride
  • Packaging10mg
  • Price$331
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5513
  • Product descriptionJNJ5207852dihydrochloride
  • Packaging50mg
  • Price$1166
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5513
  • Product descriptionJNJ5207852dihydrochloride
  • Packaging100mg
  • Price$1969
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb572889
  • Product descriptionJNJ-5207852
  • Packaging100mg
  • Price$1133.9
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6433CH 1-[4-(3-Piperidinopropoxy)benzyl]piperidine 5mg $116 2021-12-16 Buy
AK Scientific 6433CH 1-[4-(3-Piperidinopropoxy)benzyl]piperidine 10mg $132 2021-12-16 Buy
AK Scientific 6433CH 1-[4-(3-Piperidinopropoxy)benzyl]piperidine 25mg $154 2021-12-16 Buy
AK Scientific 6433CH 1-[4-(3-Piperidinopropoxy)benzyl]piperidine 50mg $192 2021-12-16 Buy
Ambeed A774214 1-(4-(3-(Piperidin-1-yl)propoxy)benzyl)piperidine 99+% 5mg $129 2021-12-16 Buy
Ambeed A774214 1-(4-(3-(Piperidin-1-yl)propoxy)benzyl)piperidine 99+% 10mg $224 2021-12-16 Buy
Ambeed A774214 1-(4-(3-(Piperidin-1-yl)propoxy)benzyl)piperidine 99+% 25mg $292 2021-12-16 Buy
Ambeed A774214 1-(4-(3-(Piperidin-1-yl)propoxy)benzyl)piperidine 99+% 50mg $380 2021-12-16 Buy
American Custom Chemicals Corporation CHM0073414 1-[4-(3-PIPERIDIN-1-YLPROPOXY)BENZYL]PIPERIDINE 95.00% 1MG $452 2021-12-16 Buy
American Custom Chemicals Corporation CHM0073414 1-[4-(3-PIPERIDIN-1-YLPROPOXY)BENZYL]PIPERIDINE 95.00% 5MG $460 2021-12-16 Buy
American Custom Chemicals Corporation CHM0073414 1-[4-(3-PIPERIDIN-1-YLPROPOXY)BENZYL]PIPERIDINE 95.00% 10MG $510 2021-12-16 Buy
ApexBio Technology B5513 JNJ5207852dihydrochloride 5mg $189 2021-12-16 Buy
ApexBio Technology B5513 JNJ5207852dihydrochloride 10mg $331 2021-12-16 Buy
ApexBio Technology B5513 JNJ5207852dihydrochloride 50mg $1166 2021-12-16 Buy
ApexBio Technology B5513 JNJ5207852dihydrochloride 100mg $1969 2021-12-16 Buy
Biorbyt Ltd orb572889 JNJ-5207852 100mg $1133.9 2021-12-16 Buy
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Properties

Boiling point :443.4±30.0 °C(Predicted)
Density :1.032±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO : 77.5 mg/mL (244.88 mM; Need ultrasonic)
form :Powder
pka :9.70±0.10(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Histamine has been implicated in a variety of biological functions including thermo- and immunoregulation, food intake, hyperexcitability, pain transmission, arousal, reward, memory, and emotional responses. The histamine H3 receptor is a Gi-coupled presynaptic auto- and hetero-receptor whose activation leads to a decreased release of histamine, glutamate, norepinephrine, and acetylcholine in the brain. H3R antagonists are expected to increase the release of these neurotransmitters, which may contribute therapeutic benefit in diseases characterized by sleep/wake disturbances or cognitive disorders. JNJ-5207852 is a selective, non-imidazole histamine H3R antagonist with high affinity at the rat (pKi = 8.9) and human (pKi = 9.24) H3 receptors. In rodents, 1-10 mg/kg JNJ-5207852 administered subcutaneously increases time spent awake and decreases REM sleep and slow-wave sleep.

Suppliers and manufacturers

career henan chemical co
1-(4-(3-piperidin-1-ylpropoxy)benzyl)piperidine
$1.00 /1KG
1-(4-(3-piperidin-1-ylpropoxy)benzyl)piperidine CAS:398473-34-2
TargetMol Chemicals Inc.
JNJ-5207852
$43.00 /5mg
JNJ-5207852 CAS:398473-34-2
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Hangzhou MolCore BioPharmatech Co.,Ltd.
TargetMol Chemicals Inc.
Chemtour Biotech Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited J & K SCIENTIFIC LTD.