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ChemicalBook >> CAS DataBase List >> N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE

N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE

N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE price.
  • $40 - $900
  • Product name: N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE
  • CAS: 405098-33-1
  • MF: C30H37ClN2O2
  • MW: 493.08
  • EINECS:
  • MDL Number:MFCD26142284
  • Synonyms:N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE;N-{[4-(diMethylaMino)phenyl]Methyl}-7-Methoxy-N-[4-(propan-2-yl)phenyl]-1,2,3,4-tetrahydronaphthalene-1-carboxaMide hydrochloride;W-54011;C5a Receptor Antagonist, W-54011;CS-2062;chemotaxis,inhibit,orally,W-54011,mobilization,anaphylatoxin,ROS,Reactive Oxygen Species,Ca2+,C5a,neutrophils,Inhibitor,Complement System,W54011,inflammatory,W 54011;N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE
Price22 Properties Safety Information Description
22 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number9144CN
  • Product descriptionC5aReceptorAntagonist,W-54011
  • Packaging10mg
  • Price$433
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9144CN
  • Product descriptionC5aReceptorAntagonist,W-54011
  • Packaging25mg
  • Price$883
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6069
  • Product descriptionW54011
  • Packaging5mg
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6069
  • Product descriptionW54011
  • Packaging10mg
  • Price$342
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6069
  • Product descriptionW54011
  • Packaging25mg
  • Price$804
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611399
  • Product descriptionW-54011
  • Packaging5mg
  • Price$493
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611399
  • Product descriptionW-54011
  • Packaging10mg
  • Price$593.3
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21231
  • Product descriptionW-54011 ≥98%
  • Packaging1mg
  • Price$40
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21231
  • Product descriptionW-54011 ≥98%
  • Packaging5mg
  • Price$187
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21231
  • Product descriptionW-54011 ≥98%
  • Packaging10mg
  • Price$315
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21231
  • Product descriptionW-54011 ≥98%
  • Packaging25mg
  • Price$737
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4889
  • Product descriptionW-54011 >98.0%
  • Packaging1mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4889
  • Product descriptionW-54011 >98.0%
  • Packaging5mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4889
  • Product descriptionW-54011 >98.0%
  • Packaging10mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4889
  • Product descriptionW-54011 >98.0%
  • Packaging50mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001974
  • Product descriptionW-54011 98+%
  • Packaging5mg
  • Price$208
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9144CN C5aReceptorAntagonist,W-54011 10mg $433 2021-12-16 Buy
AK Scientific 9144CN C5aReceptorAntagonist,W-54011 25mg $883 2021-12-16 Buy
ApexBio Technology B6069 W54011 5mg $182 2021-12-16 Buy
ApexBio Technology B6069 W54011 10mg $342 2021-12-16 Buy
ApexBio Technology B6069 W54011 25mg $804 2021-12-16 Buy
Biorbyt Ltd orb611399 W-54011 5mg $493 2021-12-16 Buy
Biorbyt Ltd orb611399 W-54011 10mg $593.3 2021-12-16 Buy
Cayman Chemical 21231 W-54011 ≥98% 1mg $40 2024-03-01 Buy
Cayman Chemical 21231 W-54011 ≥98% 5mg $187 2024-03-01 Buy
Cayman Chemical 21231 W-54011 ≥98% 10mg $315 2024-03-01 Buy
Cayman Chemical 21231 W-54011 ≥98% 25mg $737 2024-03-01 Buy
ChemScene CS-4889 W-54011 >98.0% 1mg $96 2021-12-16 Buy
ChemScene CS-4889 W-54011 >98.0% 5mg $192 2021-12-16 Buy
ChemScene CS-4889 W-54011 >98.0% 10mg $288 2021-12-16 Buy
ChemScene CS-4889 W-54011 >98.0% 50mg $900 2021-12-16 Buy
Crysdot CD31001974 W-54011 98+% 5mg $208 2021-12-16 Buy
Next Last

Properties

storage temp. :Store at -20°C
solubility :DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 3 mg/mL
form :White powder solid.
color :White to light yellow
Stability :Hygroscopic

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

C5a Receptor Antagonist, W-54011 is a potent, specific, and orally active CD88 (C5a receptor) antagonist. Shown to inhibit the binding of 125I-rhC5a to human neutrophils with a Ki of 2.2 nM, as well as C5a-induced intracellular Ca2+-mobilization, chemotaxis and reactive oxygen species (ROS) generation (IC50 = 3.1 nM, 2.7 nM and 1.6 nM, respectively) with no agonist activity up to 10 μM. Shown to prevent C5a-induced neutrophenia in gerbils (100 μg/kg i.v. or 3-30 mg/kg orally).

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Suppliers and manufacturers

TargetMol Chemicals Inc.
W-54011
$77.00 /1mg
W-54011 CAS:405098-33-1
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Guangzhou CATO Research Chemicals Inc. Haoyuan Chemexpress Co., Ltd. Shanghai EFE Biological Technology Co., Ltd. Guangzhou QiYun Biotechnology Co., Ltd. Beijing Solarbio Science & Tecnology Co., Ltd. Nanjing KaiMubo Pharmaceutical Co., Ltd. Musechem