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ChemicalBook >> CAS DataBase List >> Isopropyl 2-(acetylamino)-2-deoxy á-D-glucopyranoside 3,4,6-triacetate

Isopropyl 2-(acetylamino)-2-deoxy á-D-glucopyranoside 3,4,6-triacetate

Isopropyl 2-(acetylamino)-2-deoxy á-D-glucopyranoside 3,4,6-triacetate price.
  • $59 - $1078
  • Product name: Isopropyl 2-(acetylamino)-2-deoxy á-D-glucopyranoside 3,4,6-triacetate
  • CAS: 40592-88-9
  • MF: C17H27NO9
  • MW: 389.39758
  • EINECS:
  • MDL Number:MFCD28053519
  • Synonyms:2-Acetamidopyranoside;C34;Isopropyl 2-(acetylamino)-2-deoxy á-D-glucopyranoside 3,4,6-triacetate;TLR4-IN-C34;TLR4-C34;(2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyl diacetate;ISOPROPYL 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSIDE 3,4,6-TRIACETATE;Isopropyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranoside
25 prices
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Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Apolloscientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 5mg
  • 10
  • 10mg
  • 25mg
  • 50mg
  • 002
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number0466EC
  • Product descriptionTlr4-IN-C34
  • Packaging10mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA932319
  • Product description(2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98%
  • Packaging5mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA932319
  • Product description(2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98%
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA932319
  • Product description(2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98%
  • Packaging25mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA932319
  • Product description(2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98%
  • Packaging50mg
  • Price$263
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA932319
  • Product description(2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98%
  • Packaging100mg
  • Price$525
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA932319
  • Product description(2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98%
  • Packaging250mg
  • Price$1078
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4925
  • Product descriptionC34
  • Packaging10mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4925
  • Product descriptionC34
  • Packaging25mg
  • Price$286
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBICL4343
  • Product descriptionIsopropyl2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-glucopyranoside 98%min
  • Packaging50mg
  • Price$253
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBICL4343
  • Product descriptionIsopropyl2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-glucopyranoside 98%min
  • Packaging100mg
  • Price$377
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBICL4343
  • Product descriptionIsopropyl2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-glucopyranoside 98%min
  • Packaging250mg
  • Price$810
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18512
  • Product descriptionTLR4-C34 ≥98%
  • Packaging5mg
  • Price$73
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18512
  • Product descriptionTLR4-C34 ≥98%
  • Packaging10mg
  • Price$110
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18512
  • Product descriptionTLR4-C34 ≥98%
  • Packaging25mg
  • Price$253
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18512
  • Product descriptionTLR4-C34 ≥98%
  • Packaging50mg
  • Price$469
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0466EC Tlr4-IN-C34 10mg $220 2021-12-16 Buy
Ambeed A932319 (2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98% 5mg $59 2021-12-16 Buy
Ambeed A932319 (2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98% 10mg $80 2021-12-16 Buy
Ambeed A932319 (2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98% 25mg $132 2021-12-16 Buy
Ambeed A932319 (2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98% 50mg $263 2021-12-16 Buy
Ambeed A932319 (2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98% 100mg $525 2021-12-16 Buy
Ambeed A932319 (2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyldiacetate 98% 250mg $1078 2021-12-16 Buy
ApexBio Technology B4925 C34 10mg $123 2021-12-16 Buy
ApexBio Technology B4925 C34 25mg $286 2021-12-16 Buy
Apolloscientific BICL4343 Isopropyl2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-glucopyranoside 98%min 50mg $253 2021-12-16 Buy
Apolloscientific BICL4343 Isopropyl2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-glucopyranoside 98%min 100mg $377 2021-12-16 Buy
Apolloscientific BICL4343 Isopropyl2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-glucopyranoside 98%min 250mg $810 2021-12-16 Buy
Cayman Chemical 18512 TLR4-C34 ≥98% 5mg $73 2024-03-01 Buy
Cayman Chemical 18512 TLR4-C34 ≥98% 10mg $110 2024-03-01 Buy
Cayman Chemical 18512 TLR4-C34 ≥98% 25mg $253 2024-03-01 Buy
Cayman Chemical 18512 TLR4-C34 ≥98% 50mg $469 2024-03-01 Buy

Properties

Boiling point :519.8±50.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :H2O: soluble1mg/mL, clear (warmed)
form :powder
pka :13?+-.0.70(Predicted)
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Toll-like receptor 4 (TLR4) is activated by lipopolysaccharide (LPS), with LPS-binding protein, to initiate an innate immune response, which typically includes increased expression of TNFα. TLR4-C34 is a 2-acetamidopyranoside that inhibits TLR4 signaling in enterocytes and macrophages in vitro when used at 10 μM. It does not affect signaling through either TLR2 or TLR9. TLR4-C34, used at 1 mg/kg in vivo, also reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis. It markedly decreases the basal expression of TNFα, as well as LPS-induced iNOS and TNFα expression, in intestinal tissue isolated from patients with necrotizing enterocolitis.